After a diploma of statistician engineer from the Ensai (Ecole Nationale de la Statistique et de l’Analyse de l’Information) and a Ph.D in applied mathematics in the Statistics & Genome lab (AgroParisTech), I worked as a developer for the XLSTAT software. I have implemented some statistical methods such as mixture models, log-linear regression, mood test, bayesian hierarchical modeling CBC/HB, … Then I worked as a head teacher in statistics for one year. I was recruited in the Bioinformatic and biostatistic hub of the C3BI (Center of Bioinformatics, Biostatistics and Integrative Biology) in 2014, I am in charge of the statistical analysis and the development of R/R shiny pipelines.
Courses
Bioinformatics program for PhD students 2020-2021
This mandatory training program, required for all Institut Pasteur PhD students, begins with a group of common core courses including a knowledge base in reproducible research, R Programming and Statistics. Each student then can […]
Introduction to data analysis
This five weeks graduate level course will give participants basic skills and hands-on training in biostatistics. It will cover all the steps of an analysis workflow : design, collection, curation, hypothesis testing and data […]
Morning session – Data analysis using R
This course is an introduction to data analysis. It is better to have a minimal knowledge of R. If not, an introductory tutorial is available on the course’s web page and the basics of […]
Introduction to Data Analysis
This four-week graduate level course will give participants basic skills and hands-on training in statistics and descriptive data analysis. This course is (primarily) dedicated to first year PhD students of the Institut Pasteur (each […]
Introduction to Data Analysis
This four-week graduate level course will give participants basic skills and hands-on training in statistics and descriptive data analysis. This course is (primarily) dedicated to first year PhD students of the Institut Pasteur (each […]
Introduction to Data Analysis
This four-week graduate level course will give participants basic skills and hands-on training in statistics and descriptive data analysis. This course is (primarily) dedicated to first year PhD students of the Institut Pasteur (each […]
Projects
Software
CV
Professional Experience
Since October 2014 – Institut Pasteur – HUB Team
2013 – 2014 – Head teacher in statistics – MEDISUP sciences
Main activities: Teach statistics to first year medicine students
2012 – 2013 – Developer of algorithms and statistical methods – Addinsoft, XLSTAT software
Main activities: Implement new statistical modules for XLSTAT software. Write support and tutorials for each new methods (french/english).
2008 – 2012 – Ph.D student in applied mathematics, statistics – AgroParisTech
Subject: Semi-parametric modelisation with Markovian dependency. Main activities: Develop new statistical models to deal with spatial dependency in tiling-array data (microarrays with overlapping probes). Supervisors: Stéphane Robin and Marie-Laure Martin Magniette
Education
2012 – Ph.D in applied mathematics, statistics – AgroParisTech
2008 – Master 2 degree in mathematics, statistics option – Université de Rennes 1
2008 – Biostatistics engineer – ENSAI (Ecole Nationale de la Statistique et de l’Analyse de l’Information) – Bruz
Publications
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2020Mining zebrafish microbiota reveals key community-level resistance against fish pathogen infection., ISME J 2020 Oct 19. Online ahead of print..
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2020SHAMAN: a user-friendly website for metataxonomic analysis from raw reads to statistical analysis., BMC Bioinformatics 2020 Aug; 21(1): 345.
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2020Antiapoptotic Clone 11-Derived Peptides Induce In Vitro Death of CD4+ T Cells Susceptible to HIV-1 Infection., J Virol 2020 Jul; 94(14): .
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2020Allostatic load, emotional hyper-reactivity, and functioning in individuals with bipolar disorder, Bipolar Disord 2020 May;.
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2020Leucine-Rich Immune Factor APL1 Is Associated With Specific Modulation of Enteric Microbiome Taxa in the Asian Malaria Mosquito, Front Microbiol 2020;11:306.
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2019Ubiquitination of Virulence Factor InlC Contributes to the Host Response to Infection, mBio 2019 12;10(6).
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2019Cryptococcus neoformans resists to drastic conditions by switching to viable but non-culturable cell phenotype., PLoS Pathog 2019 07; 15(7): e1007945.
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2019Metabolic plasticity of HIV-specific CD8+ T cells is associated with enhanced antiviral potential and natural control of HIV-1 infection., Nat Metab 2019 Jul; 1(7): 704-716.
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2019Cellular Metabolism Is a Major Determinant of HIV-1 Reservoir Seeding in CD4+ T Cells and Offers an Opportunity to Tackle Infection., Cell Metab 2019 03; 29(3): 611-626.e5.
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2018Activation Levels, Cardiovascular Risk, and Functional Impairment in Remitted Bipolar Patients: Clinical Relevance of a Dimensional Approach, Psychother Psychosom 2019;88(1):45-47.
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