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About

Since September 2016, I am a research engineer in the Bioinformatics and Biostatistics HUB of the Institut Pasteur and detached in the Proteomics facility.

I have a PhD in Signal Processing from the Ecole Nationale Supérieure des Télécommunications de Bretagne (Telecom Bretagne (now IMT Atlantique)) and a Master in Mathematics with a specialty in Statistical Engineering from Rennes 1 University.

Today, most of the projects I work on consist of detecting changes in protein abundances using discovery-driven mass spectrometry. I am interested in the development of new methodologies to optimize proteomics data analysis pipelines, from the identification of peptides/proteins to their quantification and the interpretation of results. For this purpose, I worked on several R packages which can be downloaded from the CRAN and Bioconductor:

 

R Tutorials:

Quality control reports of MS-based omics data

Using Statistical Power for Sample Size estimation in MS-based omics data

Courses

09:30
15
Oct 2020
Course

Bioinformatics program for PhD students 2020-2021

This mandatory training program, required for all Institut Pasteur PhD students, begins with a group of common core courses including a knowledge base in reproducible research, R Programming and Statistics. Each student then can […]
Image Analysis Hub
Bioinformatics and Biostatistics HUB
INCEPTION – Institut Convergence for the study of Emergence of Pathology Through Individuals and Populations
Computational Biology
Center for Technological Resources and Research
Vincent Guillemot
Christophe Malabat
Jean-Yves Tinevez
Marie-Agnès Dillies
Frédéric Lemoine
Nicolas Maillet
Blaise Li
Stevenn Volant
Pascal Campagne
Hugo Varet
Hanna Julienne
Violaine Saint-André
Julien Guglielmini
Thomas Bigot
Quentin Giai Gianetto
Claudia Chica
Rachel Legendre
Adrien Pain
Natalia Pietrosemoli
Emeline Perthame
Stéphane Rigaud
Benoît Lelandais
Dmitry Ershov
Sébastien MELLA
Anđela Davidović
Thomas Obadia
Véronique Hourdel
Amine Ghozlane
Alexis Criscuolo
Amaury Vaysse
2020-10-15 09:30:00 2021-06-03 17:00:00 Europe/Paris Bioinformatics program for PhD students 2020-2021 This mandatory training program, required for all Institut Pasteur PhD students, begins with a group of common core courses including a knowledge base in reproducible research, R Programming and Statistics. Each student then can […] 25-28 Rue du Dr Roux, 75015 Paris, France
09:00
16
Jan 2017
Course

Introduction to data analysis

This five weeks graduate level course will give participants basic skills and hands-on training in biostatistics. It will cover all the steps of an analysis workflow : design, collection, curation, hypothesis testing and data […]
Bioinformatics and Biostatistics HUB
Stéphane Descorps-Declère
Marie-Agnès Dillies
Gaël Millot
Anne Biton
Stevenn Volant
Quentin Giai Gianetto
Vincent Guillemot
Nicolas Maillet
Blaise Li
Anna Zhukova
Hugo Varet
Amandine Perrin
Eric Deveaud
Bertrand Néron
2017-01-16 09:00:00 2017-02-17 13:00:00 Europe/Paris Introduction to data analysis This five weeks graduate level course will give participants basic skills and hands-on training in biostatistics. It will cover all the steps of an analysis workflow : design, collection, curation, hypothesis testing and data […] 28 Rue du Docteur Roux, Paris, France
09:00
22
Oct 2018
Course

Introduction to Data Analysis

This four-week graduate level course will give participants basic skills and hands-on training in statistics and descriptive data analysis. This course is (primarily) dedicated to first year PhD students of the Institut Pasteur (each […]
Bioinformatics and Biostatistics HUB
Marie-Agnès Dillies
Vincent Guillemot
Emeline Perthame
Hugo Varet
Stevenn Volant
Thomas Obadia
Quentin Giai Gianetto
Anne Biton
Claudia Chica
Christophe Becavin
Gaël Millot
Violaine Saint-André
2018-10-22 09:00:00 2018-11-20 00:00:00 Europe/Paris Introduction to Data Analysis This four-week graduate level course will give participants basic skills and hands-on training in statistics and descriptive data analysis. This course is (primarily) dedicated to first year PhD students of the Institut Pasteur (each […] 28 Rue du Dr Roux, Paris, France
09:00
08
Jan 2018
Course

Introduction to Data Analysis

This four-week graduate level course will give participants basic skills and hands-on training in statistics and descriptive data analysis. This course is (primarily) dedicated to first year PhD students of the Institut Pasteur (each […]
Bioinformatics and Biostatistics HUB
INCEPTION – Institut Convergence for the study of Emergence of Pathology Through Individuals and Populations
Marie-Agnès Dillies
Stéphane Descorps-Declère
Vincent Guillemot
Emeline Perthame
Hugo Varet
Stevenn Volant
Thomas Obadia
Gaël Millot
Quentin Giai Gianetto
Anne Biton
Christophe Becavin
2018-01-08 09:00:00 2018-02-02 00:00:00 Europe/Paris Introduction to Data Analysis This four-week graduate level course will give participants basic skills and hands-on training in statistics and descriptive data analysis. This course is (primarily) dedicated to first year PhD students of the Institut Pasteur (each […] 28 Rue du Docteur Roux, Paris, France
14:00
28
May 2018
Course

Analyses Protéomiques Quantitatives : Choix de méthodes et analyses des données

Public concerné : Ouvert à tous : biologistes utilisateurs des approches protéomiques par l’accès à des plate-formes de protéomique, chercheurs et ingénieurs de plate-formes protéomiques ; étudiants, Post-doc, tout personnel de laboratoires de recherche […]
Quentin Giai Gianetto
2018-05-28 14:00:00 2018-06-01 14:00:00 Europe/Paris Analyses Protéomiques Quantitatives : Choix de méthodes et analyses des données Public concerné : Ouvert à tous : biologistes utilisateurs des approches protéomiques par l’accès à des plate-formes de protéomique, chercheurs et ingénieurs de plate-formes protéomiques ; étudiants, Post-doc, tout personnel de laboratoires de recherche […] Centre de vacances du Lazaret, Sète, France

Projects

Project
Ongoing
7 Members

Phenotypic adaptation to antibiotics: t/rRNA modifications

Zeynep Baharoglu (PI)

Free-living bacteria commonly cope with and adapt to changing environments. We have shown that various families of antibiotics are capable, at concentrations as low as 1% of the MIC, to activate stress responses in […]
Project
Completed
12 Members

Insights into amebiasis using a human 3D-intestinal model (ANR-14-IFEC-0001-02)

Nancy Guillen (PI)

This project is a part of the international Infect-Era program, AMOEBAC: Entamoeba histolytica-bacterium interaction and the role of this interaction in intestinal pathogenesis (http://www.infect-era.eu/2nd-call-2014) The aim of this investigation is to understand the induced […]
Project
Ongoing
12 Members

Role of tubulin glutamylation in flagellum construction (TUBGLUFLA)

Philippe Bastin (PI)

Cilia and flagella are essential eukaryotic organelles composed of an evolutionary conserved structure of 9 doublet microtubules that are similar but not equivalent. We propose that a tubulin post-translational modification called glutamylation could act […]

Publications

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