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  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Full Professor
  • Graduate Student
  • Lab assistant
  • Non-permanent Researcher
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
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Scientific Fields
Diseases
Organisms
Applications
Technique
Starting Date
10
Nov 2020
Status
Ongoing
Members
7
Structures
4

About

ProteoCombiner is a high-performance software integrating shotgun with top-down proteomic data. The tool can deal with multiple experiments and search engines. It enables rapid and easy visualization, manual validation, and comparison of the identified proteoform sequences including the PTM characterization. We demonstrate the effectiveness of our approach on a large-scale E. coli dataset; ProteoCombiner unambiguously shortlisted proteoforms among those identified by the multiple search engines. ProteoCombiner, a demonstration video and user tutorial are freely available at https://proteocombiner.pasteur.fr, for academic use; all data are available from the ProteomeXchange consortium (identifier PXD017618).

For more info:

Lima, D. B.; Dupré, M.; Duchateau, M.; Gianetto, Q. G.; Rey, M.; Matondo, M.; Chamot-Rooke, J. ProteoCombiner: Integrating Bottom-up with Top-down Proteomics Data for Improved Proteoform Assessment. Bioinformatics 2020. https://doi.org/10.1093/bioinformatics/btaa958.