The proteomics facility, headed by Mariette Matondo, is part of the Mass Spectrometry for Biology Utechs (MSBio) directed by Julia Chamot-Rooke. The overall objective of the platform is to develop innovative bottom-up proteomics strategies to address protein function, regulation and dynamic interactions, in particular in the context of infectious diseases. Our collaborators benefit from the expertise of the staff, as well as state-of-the-art instrumentation, including the latest generation of high speed, high-resolution mass spectrometers (Orbitrap), and bioinformatics tools. The proteomics analyses provided by the platform include:
- Identification of low abundant proteins in complex biological matrices
- Advanced quantitative proteomic strategies
- Characterization of post-translational modifications (PTMs)
- Analysis and dynamics of protein complexes
- Top-Down Proteomics to identify proteoforms
Analyses can be performed either as research collaboration or service. Prior to starting the project, an experimental design is defined and the staff provides advice on sample preparation. Results are further provided after a bioinformatic analysis of the data.
User Committee members : Marco Bellinzoni, Serge Bonnefoy, Valérie Bouchez,Filipe Carvalho,Ludovic Deriano , Olivier Dussurget, Marie Flamand, Thierry Fontaine,Magdalena Gil-Tarán , Guilhem Janbon,Pierre Alexandr Kaminski, Pascale Pescher , Cosmin Saveanu, Timothy Wai.
How to work with us / How to apply for support
If you have any suggestion on how we can improve our service, please do not hesitate to contact us: Reclamation / Suggestions
On Monday at 11.00 am.
The following files link to the analysis of the surveys
We are part of the C2RT (Center for Technological Resources and Research), a center gathering the Technology and Service units (UTechS) and the technological core facilities of the campus. As such we follow the common guidelines and good practices.
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