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  • program_project
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  • Associate Professor
  • Clinical Research Assistant
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  • PhD Student
  • Physician
  • Post-doc
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  • Research Engineer
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  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
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About

Systems Bioinformatics (SysBio) incorporates systems biology approaches to characterize complex biological interactions from a holistic perspective. Our team provides Institut Pasteur’s (IP) scientific community  high level bioinformatics expertise in large-scale multi-omics data analysis derived from diverse high throughput technologies (e.g. genomics, transcriptomics, proteomics, and metabolomics).  Our methods and pipelines allow to address complex study designs integrating multiple technologies, samples, donors, time points, experimental protocols and treatments.

This approach offers unprecedented opportunities for disentangling the molecular mechanisms of biological systems, helping scientists uncover complex genotype-phenotype relationships at different scales. Yet, it requires developing robust statistical and bioinformatic tools for the integration of diverse data types, each characterized by intrinsic sources of technical and biological noise.

Laying in the intersection between systems biology and bioinformatics, our main areas of expertise include:

  • graph and network theory
  • statistical inference
  • probabilistic models

In addition to these services and research activities, we are highly involved in  the dissemination of bioinformatics and biostatistics knowledge, including  co-organizing IP’s  Department of Computational Biology seminars, organizing international workshops and providing trainings for the PhD courses, and for the Institut Pasteur International Network (RIIP).

Check out our past meetings here:

From gene expression to regulation networks (24.09.2020)

 

Courses

Introduction à l’analyse Bio-informatique de séquences

L’objectif de cette formation est de présenter, au travers de l’utilisation d’outils largement utilisés, quelques grands principes sur l’analyse de séquence. L’ensemble de la formation combine exposés théoriques (fondements méthodologiques des programmes) et applications […]

2019-09-23 09:00:00 2019-09-27 17:00:00 Europe/Paris Introduction à l’analyse Bio-informatique de séquences L’objectif de cette formation est de présenter, au travers de l’utilisation d’outils largement utilisés, quelques grands principes sur l’analyse de séquence. L’ensemble de la formation combine exposés théoriques (fondements méthodologiques des programmes) et applications […] Institut Pasteur, Rue du Docteur Roux, Paris, France

Analyse de séquences

OBJECTIFS : Les biologistes sont régulièrement confrontés à des gènes (ou des protéines) de fonctions inconnues ou mal annotés. Dans ce contexte, maîtriser quelques techniques basiques d’analyse de séquences peut se révéler d’une aide […]

2018-03-19 09:30:00 2018-09-23 17:00:00 Europe/Paris Analyse de séquences OBJECTIFS : Les biologistes sont régulièrement confrontés à des gènes (ou des protéines) de fonctions inconnues ou mal annotés. Dans ce contexte, maîtriser quelques techniques basiques d’analyse de séquences peut se révéler d’une aide […] Institut Pasteur, Rue du Docteur Roux, Paris, France

5ème école de bioinformatique AVIESAN-IFB

Initiation au traitement des données de génomique obtenues par séquençage à haut débit Objectifs Les domaines des sciences du vivant liés à l’analyse du génome ont vu au cours des dernières années une accumulation […]

2016-11-20 17:00:00 2016-11-25 17:00:00 Europe/Paris 5ème école de bioinformatique AVIESAN-IFB Initiation au traitement des données de génomique obtenues par séquençage à haut débit Objectifs Les domaines des sciences du vivant liés à l’analyse du génome ont vu au cours des dernières années une accumulation […] Station biologique de Roscoff, Place Georges Teissier, Roscoff, France

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Courses

This course, organized and tought by FunGen, was designed upon request of the Institut Pasteur to offer a yearly training presenting the main principles of sequence analysis through the use of speciliased web sites. It provides both ground theoretical basis and practical criteria allowing the students to use sequences analysis tools.