Genomic studies of grouped cases involving rare yeast species
Genotyping method such as microsatellites and MultiLocus Sequence Typing (MLST) are frequently used to confirm the link between isolates responsible of invasive infections. But these methods are only available for frequent fungal species. For […]
Bioweb is a web portal to search and access the bioinformatics resources available at the Institut Pasteur. It provides an overview of the resources available in the central infrastructure, as well as features to identify […]
Candida albicans genomic diversity and its underlying mechanisms
Following our introduction of Multi-Locus Sequence Typing (MLST) as the state-of-the-art methodology for molecular epidemiology studies of C. albicans, the Fungal Biology and Pathogenicity Unit at Institut Pasteur is now progressing into population genomics […]
Private: The Candida albicans ORFeome Project
The advent of the genomic era has made elucidating gene function at large scale a pressing challenge. ORFeome collections, whereby almost all ORFs of a given species are cloned and can be subsequently leveraged […]
2019Within-Host Genomic Diversity of Candida albicans in Healthy Carriers, Sci Rep 2019 Feb;9(1):2563.
2019Identification of Recessive Lethal Alleles in the Diploid Genome of a Candida albicans Laboratory Strain Unveils a Potential Role of Repetitive Sequences in Buffering Their Deleterious Impact, mSphere 2019 Feb;4(1).
2018Generating genomic platforms to study Candida albicans pathogenesis, Nucleic Acids Res. 2018 Aug;46(14):6935-6949.
2018Gene flow contributes to diversification of the major fungal pathogen Candida albicans, Nat Commun 2018 Jun;9(1):2253.
2016Analysis of Repair Mechanisms following an Induced Double-Strand Break Uncovers Recessive Deleterious Alleles in the Candida albicans Diploid Genome, MBio 2016 Oct;7(5).
2015A FACS-optimized screen identifies regulators of genome stability in Candida albicans, Eukaryotic Cell 2015 Mar;14(3):311-22.
2014A preliminary study of viral metagenomics of French bat species in contact with humans: identification of new mammalian viruses, PLoS ONE 2014;9(1):e87194.
2013Genomic characterization of Sebokele virus 1 (SEBV1) reveals a new candidate species among the genus Parechovirus, J. Gen. Virol. 2013 Jul;94(Pt 7):1547-53.
2009Mobyle: a new full web bioinformatics framework, Bioinformatics 2009 Nov;25(22):3005-11.