Timeline

Jean-Marc Ghigo
Head of Structure
27 Mar 2024
publication

Bile-induced biofilm formation in Bacteroides thetaiotaomicron requires magnesium efflux by an RND pump.

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02 Dec 2023
publication

Analysis of in-patient evolution of Escherichia coli reveals potential links to relapse of bone and joint infections.

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23 Nov 2023
publication

The Mla system of diderm Firmicute Veillonella parvula reveals an ancestral transenvelope bridge for phospholipid trafficking.

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11 Nov 2023
publication

Anti-diarrheal drug loperamide induces dysbiosis in zebrafish microbiota via bacterial inhibition.

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17 Aug 2023
publication

Characterization of Pseudomonas aeruginosa l,d-Transpeptidases and Evaluation of Their Role in Peptidoglycan Adaptation to Biofilm Growth.

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17 Aug 2023
publication

Escherichia coli SPFH Membrane Microdomain Proteins HflKC Contribute to Aminoglycoside and Oxidative Stress Tolerance.

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03 May 2023
publication

Bacterial capsular polysaccharides with antibiofilm activity share common biophysical and electrokinetic properties.

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11 Apr 2023
publication

Escherichia coli Aggregates Mediated by Native or Synthetic Adhesins Exhibit Both Core and Adhesin-Specific Transcriptional Responses.

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16 Mar 2023
publication

Intermittent antibiotic treatment of bacterial biofilms favors the rapid evolution of resistance.

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02 Mar 2023
publication

Chromosomal Position of Ribosomal Protein Genes Affects Long-Term Evolution of Vibrio cholerae.

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28 Feb 2023
publication

Exposure to Secreted Bacterial Factors Promotes HIV-1 Replication in CD4+ T Cells.

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01 Jan 2023
publication

Secreted peptidases contribute to virulence of fish pathogen Flavobacterium columnare.

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16 Dec 2022
publication

Bacterial crystalline cellulose secretion via a supramolecular BcsHD scaffold

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23 Nov 2022
event

Dept Microbiology | Seminar “Diet shapes evolution of a key member of the gut microbiota ”

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17 Oct 2022
publication

Flavobacterium columnare ferric iron uptake systems are required for virulence

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21 Sep 2022
publication

Pseudomonas aeruginosa Production of Hydrogen Cyanide Leads to Airborne Control of Staphylococcus aureus Growth in Biofilm and In Vivo Lung Environments

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05 Apr 2022
publication

Selection for nonspecific adhesion is a driver of FimH evolution increasing Escherichia coli biofilm capacity

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01 Mar 2022
publication

An ancient divide in outer membrane tethering systems in bacteria suggests a mechanism for the diderm-to-monoderm transition.

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15 Feb 2022
publication

Bacteroides thetaiotaomicron uses a widespread extracellular DNase to promote bile-dependent biofilm formation.

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08 Feb 2022
publication

Type IX Secretion System Effectors and Virulence of the Model Flavobacterium columnare Strain MS-FC-4.

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01 Jan 2022
publication

Flavobacterium columnare ferric iron uptake systems are required for virulence.

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25 Nov 2021
publication

Gut biofilms: Bacteroides as model symbionts to study biofilm formation by intestinal anaerobes.

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03 Aug 2021
project

Supplementary Tables for BioRxiv

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05 Jul 2021
publication

Sustainable plant-based diets promote rainbow trout gut microbiota richness and do not alter resistance to bacterial infection.

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13 Apr 2021
publication

Lifestyle-specific S-nitrosylation of protein cysteine thiols regulates Escherichia coli biofilm formation and resistance to oxidative stress.

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01 Mar 2021
publication

Mining zebrafish microbiota reveals key community-level resistance against fish pathogen infection.

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06 Jan 2021
publication

On the strong connection between nanoscale adhesion of Yad fimbriae and macroscale attachment of Yad-decorated bacteria to glycosylated hydrophobic and hydrophilic surfaces

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01 Jan 2021
publication

Gnotobiotic rainbow trout (Oncorhynchus mykiss) model reveals endogenous bacteria that protect against Flavobacterium columnare infection.

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25 Sep 2020
publication

Visualizing the dynamics of exported bacterial proteins with the chemogenetic fluorescent reporter FAST

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03 Sep 2020
publication

Growth performance and adaptability of European sea bass (Dicentrarchus labrax) gut microbiota to alternative diets of fish products

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17 Aug 2020
publication

Autotransporters drive biofilm formation and auto-aggregation in the diderm Firmicute Veillonella parvula

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03 Jul 2020
publication

In situ monitoring of exopolymer-dependent Mn mineralization on bacterial surfaces

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23 Jun 2020
publication

Capsular polysaccharide cross-regulation modulates Bacteroides thetaiotaomicron biofilm formation

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23 Jun 2020
publication

Capsular Polysaccharide Cross-Regulation Modulates Bacteroides thetaiotaomicron Biofilm Formation.

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17 Jul 2019
publication

Definitions and Guidelines for Research on Antibiotic Persistence

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24 May 2019
publication

Zinc acetate potentiates the action of tosufloxacin on Escherichia coli biofilm persisters

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04 Mar 2019
publication

A putative type V pilus contributes to Bacteroides thetaiotaomicron biofilm formation capacity

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25 Feb 2019
project

Biofilms formed by anaerobes

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19 Feb 2019
publication

Biofilms 2018: A diversity of microbes and mechanisms

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20 Jan 2019
publication

Engineered toxin-intein antimicrobials can selectively target and kill antibiotic-resistant bacteria in mixed populations

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20 Aug 2018
publication

Clostridium difficile biofilm: remodeling metabolism and cell surface to build a sparse and heterogeneously aggregated architecture

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20 Jul 2018
publication

Increased osmolarity in biofilm triggers RcsB-dependent lipid A palmitoylation in Escherichia coli

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01 Jun 2018
publication

Probing the influence of cell surface polysaccharides on nanodendrimer binding to Gram-negative and Gram-positive bacteria using single-nanoparticle force spectroscopy

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16 Mar 2018
news

Asymmetric adhesion of rod-shaped bacteria controls microcolony morphogenesis

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16 Mar 2018
publication

Asymetric adhesion in rod-shaped bacteria controls microcolony morphogenesis

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06 Jan 2018
event

8th ASM Conference on Biofilms

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06 Jan 2018
project

Molecular Bases of Colonization Resistance

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27 Sep 2017
publication

Comparative Analysis of Bacterial Community Composition and Structure in Clinically Symptomatic and Asymptomatic Central Venous Catheters

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26 Sep 2017
news

Insights into the structure and assembly of a cellulose secretion system. 

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25 Sep 2017
publication

Insights into the structure and assembly of a bacterial cellulose secretion system

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12 Sep 2017
publication

YeeJ is an inverse autotransporter from Escherichia coli that binds to peptidoglycan and promotes biofilm formation

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10 Sep 2017
publication

Long-term stability of gentamicin sulfate-ethylenediaminetetraacetic acid disodium salt (EDTA-Na2) solution for catheter locks

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01 Jul 2017
publication

Recent advances in studying single bacteria and biofilm mechanics

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15 May 2017
news

Biofilm-associated production of 1-Propanol in Enterobacteriacae

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10 May 2017
publication

Biofilm microenvironment induces a widespread adaptive amino-acid fermentation pathway conferring strong fitness advantage in Escherichia coli

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01 Jan 2017
publication

Biological and chemical strategies for exploring inter- and intrakingdom communication mediated via bacterial volatile signals.

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31 Aug 2016
publication

Functional analysis of Escherichia coli Yad fimbriae reveals their potential role in environmental persistence

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01 Jun 2016
publication

Ultimate single-copy DNA detection using real-time electrochemical LAMP

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08 Apr 2016
event

Journées du Département de Microbiologie

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14 Mar 2016
publication

Biofilms 2015: Multi-disciplinary approaches shed light into microbial life on surfaces

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11 Mar 2016
publication

Study of in vivo catheter biofilm infections using pediatric central venous catheter implanted in rat

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08 Dec 2015
publication

Airborne bacterial interactions: Functions out of thin air?

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06 Aug 2015
tool

Genetic Methods and Tools

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06 Aug 2015
tool

In vivo Study of Biofilm-Associated Catheter Infections

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02 Aug 2015
project

Biofilm formation

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24 Jul 2015
project

Mixed Biofilms

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23 Jul 2015
tool

Biofilm Microfermenters

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23 Jul 2015
publication

In memoriam: A tribute to Cecile Wandersman

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17 Jul 2015
project

When Gut Bacteria Changes Brain Functions

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06 Jul 2015
publication

Systematic nomenclature for GGDEF and EAL domain-containing c-di-GMP turnover proteins of Escherichia coli.

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06 Jul 2015
publication

Selective propensity of bovine jugular vein material to bacterial adhesions: An in-vitro study.

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02 Jul 2015
project

Biofilm physiology

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16 Jun 2015
project

Biofilm Tolerance to Antibiotics

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01 Jun 2015
publication

Mechanisms of Competition in Biofilm Communities

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11 May 2015
team

Genetics of Biofilms

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23 Feb 2015
publication

In vitro activity of gentamicin, vancomycin or amikacin combined with EDTA or l-arginine as lock therapy against a wide spectrum of biofilm-forming clinical strains isolated from catheter-related infections

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17 Feb 2015
project

Smelling bacteria

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14 Feb 2015
publication

Inhibition of type 1 fimbriae-mediated Escherichia coli adhesion and biofilm formation by trimeric cluster thiomannosides conjugated to diamond nanoparticles.

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02 Feb 2015
publication

Role of bacterial volatile compounds in bacterial biology

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01 Feb 2015
project

Biofilm Volatile Compounds

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03 Jan 2015
project

Fighting biofilms

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01 Jan 2015
project

Biophysics of Bacteria-Surface Interactions

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10 Nov 2014
publication

Dynamic modulation of fimbrial extension and FimH-mannose binding force on live bacteria under pH changes: a molecular atomic force microscopy analysis.

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01 Nov 2014
publication

The dynamics and pH-dependence of Ag43 adhesins’ self-association probed by atomic force spectroscopy

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23 Sep 2014
publication

Novel approaches to combat bacterial biofilms

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10 Sep 2014
publication

[Infections related to implanted medical devices: the down-side of medical progress]

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01 Sep 2014
publication

Methods for studying biofilm dispersal in Pseudomonas aeruginosa.

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01 Sep 2014
publication

Biofilm-related infections: bridging the gap between clinical management and fundamental aspects of recalcitrance toward antibiotics

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19 Aug 2014
publication

Biofilms formed by gram-negative bacteria undergo increased lipid A palmitoylation enhancing in vivo survival

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05 Aug 2014
publication

In vivo mRNA profiling of uropathogenic Escherichia coli from diverse phylogroups reveals common and group-specific gene expression profiles.

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23 Jul 2014
publication

Bacteria hold their breath upon surface contact as shown in a strain of Escherichia coli, using dispersed surfaces and flow cytometry analysis

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15 May 2014
publication

pH-mediated potentiation of aminoglycosides kills bacterial persisters and eradicates in vivo biofilms

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01 May 2014
publication

Preventing biofilm formation and associated occlusion by biomimetic glycocalyxlike polymer in central venous catheters

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01 May 2014
publication

Implanted medical device-related infections: pathophysiology and prevention [article in French]

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01 Apr 2014
publication

Biofilm tolerance towards antibiotics: Mechanisms and treatment

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01 Apr 2014
publication

Azithromycin analogue CSY0073 attenuates lung inflammation induced by LPS challenge

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03 Feb 2014
publication

In Vitro Activities of Dermaseptins K4S4 and K4K20S4 against Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa Planktonic Growth and Biofilm Formation

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01 Feb 2014
publication

Management of infections related to totally implantable venous-access ports: challenges and perspectives

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23 Jan 2014
publication

A new biofilm-associated colicin with increased efficiency against biofilm bacteria

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07 Jan 2014
publication

Aerial exposure to the bacterial volatile compound trimethylamine modifies antibiotic resistance of physically separated bacteria by raising culture medium pH

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20 Dec 2013
publication

Bacterial biofilm mechanical properties persist upon antibiotic treatment and survive cell death

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04 Oct 2013
publication

Induction of the Cpx envelope stress pathway contributes to Escherichia coli tolerance to antimicrobial peptides

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23 Sep 2013
publication

Sugar-modified foldamers as conformationally defined and biologically distinct glycopeptide mimics.

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05 Sep 2013
publication

Did I pick the right colony? Pitfalls in the study of regulation of the phase variable antigen 43 adhesin

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03 Jun 2013
publication

Escherichia coli resistance to nonbiocidal antibiofilm polysaccharides is rare and mediated by multiple mutations leading to surface physicochemical modifications

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07 May 2013
publication

Identification of commensal Escherichia coli genes involved in biofilm resistance to pathogen colonization

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21 Mar 2013
publication

Biofilms 5 International Conference: meeting report

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21 Mar 2013
publication

Glycan-functionalized diamond nanoparticles as potent E. coli anti-adhesives

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03 Jan 2013
publication

Starvation, together with the SOS response, mediates high biofilm-specific tolerance to the fluoroquinolone ofloxacin

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01 Oct 2012
publication

Full and broad-spectrum in vivo eradication of catheter-associated biofilms using gentamicin-EDTA antibiotic lock therapy

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19 Sep 2012
publication

Mapping of bacterial biofilm local mechanics by magnetic microparticle actuation

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22 Aug 2012
publication

[Management of biofilm-associated infections: what can we expect from recent research on biofilm lifestyles?]

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17 Aug 2012
publication

Functional heterogeneity of the UpaH autotransporter protein from uropathogenic Escherichia coli

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26 Jul 2012
publication

A new zebrafish model of oro-intestinal pathogen colonization reveals a key role for adhesion in protection by probiotic bacteria

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26 Jun 2012
publication

Antibiofilm polysaccharides

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19 Jun 2012
publication

The bacterial thiopurine methyltransferase tellurite resistance process is highly dependent upon aggregation properties and oxidative stress response

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16 May 2012
publication

A rat model of central venous catheter to study establishment of long-term bacterial biofilm and related acute and chronic infections

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08 Mar 2012
publication

Multi-species biofilms: how to avoid unfriendly neighbors

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27 Jan 2012
publication

Molecular characterization of the EhaG and UpaG trimeric autotransporter proteins from pathogenic Escherichia coli

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01 Jan 2012
publication

Molecular characterization of UpaB and UpaC, two new autotransporter proteins of uropathogenic Escherichia coli CFT073

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23 Jun 2011
publication

Biogenic ammonia modifies antibiotic resistance at a distance in physically separated bacteria

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31 May 2011
publication

Bacterial surface appendages strongly impact nanomechanical and electrokinetic properties of Escherichia coli cells subjected to osmotic stress

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10 May 2011
publication

Screening of Escherichia coli species biodiversity reveals new biofilm-associated antiadhesion polysaccharides

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22 Feb 2011
publication

The sweet connection: Solving the riddle of multiple sugar-binding fimbrial adhesins in Escherichia coli: Multiple E. coli fimbriae form a versatile arsenal of sugar-binding lectins potentially involved in surface-colonisation and tissue tropism

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08 Oct 2010
publication

Silent mischief: bacteriophage Mu insertions contaminate products of Escherichia coli random mutagenesis performed using suicidal transposon delivery plasmids mobilized by broad-host-range RP4 conjugative machinery

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23 Mar 2010
publication

Escherichia coli K-12 possesses multiple cryptic but functional chaperone-usher fimbriae with distinct surface specificities

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26 Aug 2009
publication

Biofilm-forming Pseudomonas aeruginosa bacteria undergo lipopolysaccharide structural modifications and induce enhanced inflammatory cytokine response in human monocytes

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01 May 2009
publication

BcsQ is an essential component of the Escherichia coli cellulose biosynthesis apparatus that localizes at the bacterial cell pole

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23 Jan 2009
publication

Organised genome dynamics in the Escherichia coli species results in highly diverse adaptive paths

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01 Oct 2008
publication

Impact of rpoS deletion on the proteome of Escherichia coli grown planktonically and as biofilm

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01 Jul 2008
publication

A short-time scale colloidal system reveals early bacterial adhesion dynamics

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18 Apr 2008
publication

UpaG, a new member of the trimeric autotransporter family of adhesins in uropathogenic Escherichia coli

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01 Mar 2008
publication

The characterization of functions involved in the establishment and maturation of Klebsiella pneumoniae in vitro biofilm reveals dual roles for surface exopolysaccharides.

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01 Jan 2008
publication

Escherichia coli biofilms

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02 Nov 2007
publication

The amino acid valine is secreted in continuous-flow bacterial biofilms

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09 Apr 2007
publication

Functional analysis of antigen 43 in uropathogenic Escherichia coli reveals a role in long-term persistence in the urinary tract

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23 Mar 2007
publication

Tight modulation of Escherichia coli bacterial biofilm formation through controlled expression of adhesion factors

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07 Aug 2006
publication

Broad-spectrum biofilm inhibition by a secreted bacterial polysaccharide

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01 Apr 2006
publication

A CsgD-independent pathway for cellulose production and biofilm formation in Escherichia coli

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01 Apr 2006
publication

An IncI1 plasmid contributes to the adherence of the atypical enteroaggregative Escherichia coli strain C1096 to cultured cells and abiotic surfaces

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01 Feb 2006
publication

The transcriptional antiterminator RfaH represses biofilm formation in Escherichia coli

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01 Dec 2005
publication

BapA, a large secreted protein required for biofilm formation and host colonization of Salmonella enterica serovar Enteritidis

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29 Aug 2005
publication

Colonization of abiotic surfaces

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01 Mar 2005
publication

CpxR/OmpR interplay regulates curli gene expression in response to osmolarity in Escherichia coli

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15 Feb 2005
publication

Combined inactivation and expression strategy to study gene function under physiological conditions: application to identification of new Escherichia coli adhesins

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01 Feb 2005
publication

The Yak1p kinase controls expression of adhesins and biofilm formation in Candida glabrata in a Sir4p-dependent pathway

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01 Jan 2005
publication

Finding gene-expression patterns in bacterial biofilms

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01 Aug 2004
publication

Haemophore-mediated signalling in Serratia marcescens: a new mode of regulation for an extra cytoplasmic function (ECF) sigma factor involved in haem acquisition

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01 Jun 2004
publication

Excision of the high-pathogenicity island of Yersinia pseudotuberculosis requires the combined actions of its cognate integrase and Hef, a new recombination directionality factor

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01 Apr 2004
publication

Candida albicans biofilms: a developmental state associated with specific and stable gene expression patterns

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01 Feb 2004
publication

Global impact of mature biofilm lifestyle on Escherichia coli K-12 gene expression

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22 Sep 2003
publication

A rapid and simple method for inactivating chromosomal genes in Yersinia

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01 Sep 2003
publication

A new evaluation of our life-support system

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01 Jun 2003
publication

Haemophore-mediated signal transduction across the bacterial cell envelope in Serratia marcescens: the inducer and the transported substrate are different molecules

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01 May 2003
publication

SarA and not sigmaB is essential for biofilm development by Staphylococcus aureus

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01 Jan 2003
publication

Are there biofilm-specific physiological pathways beyond a reasonable doubt?

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01 Feb 2002
publication

Genetic analysis of Salmonella enteritidis biofilm formation: critical role of cellulose

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01 Nov 2001
publication

Identification and characterization of the hemophore-dependent heme acquisition system of Yersinia pestis

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01 Nov 2001
publication

Characterization of HasB, a Serratia marcescens TonB-like protein specifically involved in the haemophore-dependent haem acquisition system

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26 Jul 2001
publication

Natural conjugative plasmids induce bacterial biofilm development

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15 Nov 2000
publication

A rapid method for efficient gene replacement in the filamentous fungus Aspergillus nidulans.

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01 Jan 2000
publication

Cell division in Escherichia coli: role of FtsL domains in septal localization, function, and oligomerization

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31 Jan 1999
publication

Localization of FtsL to the Escherichia coli septal ring

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01 Jan 1999
publication

Localization of FtsI to the septal ring requires the Z ring, FtsA, FtsQ, and FtsL. Journal of Bacteriology 181:508-20.

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01 Jan 1999
publication

Septal localization of FtsQ, an essential cell division protein in Escherichia coli

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11 Jun 1997
publication

Protein secretion by gram-negative bacterial ABC exporters

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11 Jun 1997
publication

Protein secretion by Gram-negative bacterial ABC exporters-a review.

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01 Jun 1997
publication

A new hemophore-dependent heme acquisition system of Serratia marcescens reconstituted in Escherichia coli

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11 Oct 1994
publication

Iron acquisition from heme and hemoglobin by a Serratia marcescens extracellular protein

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01 Sep 1994
publication

Secretion of the Serratia marcescens HasA protein by an ABC transporter

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25 Mar 1994
publication

A carboxyl-terminal four-amino acid motif is required for secretion of the metalloprotease PrtG through the Erwinia chrysanthemi protease secretion pathway.

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01 Nov 1993
publication

Identification of two components of the Serratia marcescens metalloprotease transporter: protease SM secretion in Escherichia coli is TolC dependent

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01 Dec 1992
publication

Cloning, nucleotide sequence and characterization of the gene encoding the Erwinia chrysanthemi B374 PrtA metalloprotease: a third metalloprotease secreted via a C-terminal secretion signal.

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01 Nov 1992
publication

A fourth metalloprotease gene in Erwinia chrysanthemi

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01 Feb 1992
publication

A signal peptide-independent protein secretion pathway

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