Search anything and hit enter
  • Teams
  • Members
  • Projects
  • Events
  • Calls
  • Jobs
  • publications
  • Software
  • Tools
  • Network
  • Equipment

A little guide for advanced search:

  • Tip 1. You can use quotes "" to search for an exact expression.
    Example: "cell division"
  • Tip 2. You can use + symbol to restrict results containing all words.
    Example: +cell +stem
  • Tip 3. You can use + and - symbols to force inclusion or exclusion of specific words.
    Example: +cell -stem
e.g. searching for members in projects tagged cancer
Search for
Count
IN
OUT
Content 1
  • member
  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Clinical Research Nurse
  • Clinician Researcher
  • Department Manager
  • Dual-education Student
  • Full Professor
  • Honorary Professor
  • Lab assistant
  • Master Student
  • Non-permanent Researcher
  • Nursing Staff
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Prize
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
Content 2
  • member
  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Clinical Research Nurse
  • Clinician Researcher
  • Department Manager
  • Dual-education Student
  • Full Professor
  • Honorary Professor
  • Lab assistant
  • Master Student
  • Non-permanent Researcher
  • Nursing Staff
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Prize
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
Search
Go back
Scroll to top
Share
© J.M. Ghigo (Institut Pasteur) and Brigite Arbeille (LBC-ME. Faculté de Médecine de Tours)
Colorized scanning electron microscopy of an E. coli biofilm developing on a glass surface
Scientific Fields
Diseases
Organisms
Applications
Technique

About

Biofilms are communities of microorganisms that interact with surfaces, and are known to display unique properties that differentiate them from free-floating, individual microorganisms. While biofilms are widespread and play many positive roles in all environments, they are also difficult to eradicate when adhered to surfaces in medical and industrial settings.

We use genetics, genomics, molecular biology, and various in vitro and in vivo biofilm models to better understand biofilm-associated functions used by commensal and pathogenic bacteria. We also attempt to translate our fundamental approaches into relevant anti-biofilm strategies in collaboration with clinicians and industrial partners.

Thiriet-Rupert S, Josse J, Pérez-Pascual D, Tasse J, Andre C, Abad L, Lebeaux D, Ghigo JM, Laurent F, Beloin C (2023) Analysis of in-patient evolution of Escherichia coli reveals potential links to relapse of bone and joint infections. The Journal of Infectious Diseases, Dec 2:jiad528. doi: 10.1093/infdis/jiad528.

Grasekamp KP, Beaud B, Taib N, Audrain B, Bardiaux B, Rossez Y, Izadi-Pruneyre N, Lejeune M, Trivelli X, Chouit Z, Guerardel Y, Ghigo JM, Gribaldo S, Beloin C (2023) Bridges instead of boats? The Mla system of the diderm Firmicute Veillonella parvula is an ancestral envelope-spanning core of phospholipid trafficking. Nature Communications, Nov 23;14(1):7642. doi: 10.1038/s41467-023-43411-y.

Stevick RJ, Audrain B, Bedu S, Dray N, Ghigo JM, Pérez-Pascual D (2023) Anti-diarrheal drug loperamide induces dysbiosis in zebrafish microbiota via bacterial inhibition. Microbiome,Nov 11;11(1):252. doi:10.1186/s40168-023-01690-z.

Bernal-Bayard J, Thiebaud J, Brossaud MJ, Beaussart A, Caillet C, Waldvogel Y, Travier L,Létoffé S, Fontaine T, Rokbi B, Talaga P, Beloin C., Mistretta N*, Duval JFL*, Ghigo JM*. (2023) Bacterial capsular polysaccharides with antibiofilm activity share common biophysical and electrokinetic properties. Nature Communications. May 3;14(1):2553. doi: 10.1038/s41467-023-37925-8. 

Wessel AK, Yoshii Y, Reder A, Szczesny M, Boudjemaa R, Betton JM, Bernal-Bayard J, Beloin C, Lopez D, Völker U, Ghigo JM (2023) Escherichia coli SPFH membrane microdomain proteins HflKC contributes to aminoglycoside and oxidative stress tolerance. Microbiology Spectrum,Jun 22;e0176723.doi: 10.1128/spectrum.01767-23.

Masaru Usui, Yutaka Yoshii, Stanislas Thiriet-Rupert Jean-Marc Ghigo and Christophe Beloin. (2023) Intermitent antibiotic treatment of bacterial biofilms favors the rapid evolution of resistance. Communications Biology Mar 16;6(1):275. doi: 10.1038/s42003-023-04601-y.

Members

Former Members

Lab “History” Chart

( click to enlarge )

Where are they now?

( click to enlarge )

Projects

Transversal Project

Tools

Fundings

Featured publications

Download

Pictures & Media

Group Pictures.OK

Visit the lab.OK

Thesishat.OK

PASTSUPPORT

Contact

Prof. Jean-Marc GHIGO

  • Email: jmghigo [@] pasteur.fr
  • Phone: + 33 (0)1 40 61 34 18

Mrs Pascale SITBON (secretary)

  • Email: pascale.sitbon [@] pasteur.fr
  • Phone: + 33 (0)1 40 61 38 19 (morning only)

Postal address of the Laboratory

Address in english Address in french
INSTITUT PASTEUR Prof. Jean-Marc GHIGO Genetics of Biofilms Laboratory Duclaux Bldg, Fourneau wing, R+2 28 Rue du Docteur Roux 75724 Paris Cedex 15 FRANCE INSTITUT PASTEUR Prof. Jean-Marc GHIGO Unité de Génétique des Biofilms Bat. Duclaux , aile Fourneau, 2ème étage 28 Rue du Docteur Roux 75724 Paris Cedex 15 FRANCE

How to get to the Institut Pasteur: Click to enlarge