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  • Research Engineer
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  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
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  • Deputy Head of Facility
  • Director of Center
  • Director of Department
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© J.M. Ghigo (Institut Pasteur) and Brigite Arbeille (LBC-ME. Faculté de Médecine de Tours)
Colorized scanning electron microscopy of an E. coli biofilm developing on a glass surface
Scientific Fields
Diseases
Organisms
Applications
Technique
Starting Date
01
Jan 2002
Ending Date
31
Dec 2020
Status
Ongoing
Members
2
Structures
2
Publications
11

About

Biofilm formation relies as much on bacterial adhesion properties than on surface chemistry, and many questions remain regarding biophysics of surface adhesion. In collaboration with physico-chemists and biophysicists, we used multidisciplinary approaches to investigate bacterial adaptations to surface contact and biomechanical properties of adhesins.

Recent articles on this topic

• Duvernoy, M.-C., T. Mora, M. Ardre, V. Croquette, D. Bensimon, C. Quilliet, J.-M. Ghigo, M. Balland, C. Beloin, S. Lecuyer, and N. Desprat. (2018). Asymetric adhesion in rod-shaped bacteria controls microcolony morphogenesis. Nature Communications.  Mar 16;9(1):1120. doi: 10.1038/s41467-018-03446-y

• Beaussart A., C. Beloin, J.-M. Ghigo, M.-P. Chapot-Chartier, S. Kulalauskas, and J.F.L. Duval (2018). Probing the influence of cell surface polysaccharides on nanodendrimer binding to Gram-negative and Gram-positive bacteria using single-nanoparticle force spectroscopy. Nanoscale. Jul 9;10(26):12743-12753. Doi:10.1039/c8nr01766b.

Review on this topic

•  Catherine Even, Christian Marlière, Jean-Marc Ghigo, Jean-Marc Allain, Alba Marcellan, Eric Raspaud. Recent advances in studying single bacteria and biofilm mechanics. (2017). Advances in Colloids and Interface science. Sep;247:573-588. doi: 10.1016/j.cis.2017.07.026.

References