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© J.M. Ghigo (Institut Pasteur) and Brigite Arbeille (LBC-ME. Faculté de Médecine de Tours)
Colorized scanning electron microscopy of an E. coli biofilm developing on a glass surface
Publication : Trends in microbiology

Finding gene-expression patterns in bacterial biofilms

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Trends in microbiology - 01 Jan 2005

Beloin C, Ghigo JM

Link to Pubmed [PMID] – 15639627

Trends Microbiol. 2005 Jan;13(1):16-9

The production of biofilms by bacteria is a lifestyle that is thought to require or involve a differential gene expression compared with that of planktonic bacteria. Recently, we have witnessed a change of focus from the simple hunt for hypothetical essential biofilm genes to the identification of late and more complex biofilm functions. However, finding common bacterial biofilm gene-expression patterns through global expression analysis remains difficult. Owing to the apparently minimal overlap between functions involved in biofilm formation by different bacteria, exploring the biofilm lifestyle could prove to be a case-by-case task for which global approaches show their limits.

http://www.ncbi.nlm.nih.gov/pubmed/15639627