Timeline

Christophe D’Enfert
Head of Structure
29 Jul 2019
event

Candida albicans invasion into epithelial layers: Integrating dynamics, structure and function at the pathogen-host interface- Allon Weiner

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04 Jun 2019
event

French-Brazilian Symposium on Fungal Pathogens

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25 Apr 2019
publication

Biofilms Are Generally Devoid of Persister Cells

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25 Apr 2019
publication

Studying fungal pathogens of humans and fungal infections: fungal diversity and diversity of approaches

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15 Mar 2019
event

Genetic and Epigenetic Mechanisms Driving Phenotypic Diversity in Pathogenic Candida Species – Richard Bennett

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14 Mar 2019
publication

One step ahead: Innovation in core facilities

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28 Feb 2019
publication

Candida albicans: An Emerging Yeast Model to Study Eukaryotic Genome Plasticity

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22 Feb 2019
publication

Within-Host Genomic Diversity of Candida albicans in Healthy Carriers

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13 Feb 2019
publication

Identification of Recessive Lethal Alleles in the Diploid Genome of a Candida albicans Laboratory Strain Unveils a Potential Role of Repetitive Sequences in Buffering Their Deleterious Impact

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07 Jan 2019
event

Mini-symposium: Kick-off meeting of the FunHoMic Marie Curie Innovative Training Network – Deciphering the fungus-host-microbiota interplay to improve the management of fungal infections

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07 Jan 2019
project

FunHoMic MC-ITN: Deciphering the fungus-host-microbiota interplay to improve the management of fungal infections

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14 Dec 2018
event

“Understanding antifungal drug resistance and tolerance in fungal pathogens : impact of genomics” Dominique Sanglard

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02 Nov 2018
publication

Evolving a pathogen to be protective

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28 Oct 2018
publication

From Genes to Networks: The Regulatory Circuitry Controlling Candida albicans Morphogenesis

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27 Sep 2018
tool

Private: The Candida albicans ORFeome Project

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07 Sep 2018
event

Phd Thesis defense “La Candidose cutanéo-muqueuse chronique : un modèle d’étude de l’adaptation génomique chez C.albicans “

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22 Aug 2018
publication

A High-Throughput Two-Hybrid System

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21 Aug 2018
publication

Generating genomic platforms to study Candida albicans pathogenesis

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03 Aug 2018
publication

Combined bacterial and fungal intestinal microbiota analyses: Impact of storage conditions and DNA extraction protocols

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11 Jul 2018
publication

Systematic gene overexpression in Candida albicans identifies a regulator of early adaptation to the mammalian gut

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03 Jul 2018
center

Center for Animal Resources and Research

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03 Jul 2018
center

Center for Technological Resources and Research

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14 Jun 2018
publication

Methodologies for and evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms

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08 Jun 2018
publication

Gene flow contributes to diversification of the major fungal pathogen Candida albicans

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07 Feb 2018
event

“Candida albicans centromere biology” by Kaustuv SANYAL – Mycology Department Seminar

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20 Nov 2017
publication

Azole resistance in a mutant lacking the ABC transporter depends on TOR signaling

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16 Nov 2017
publication

A standardized toolkit for genetic engineering of CTG clade yeasts

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28 Jul 2017
publication

The two-component response regulator Skn7 belongs to a network of transcription factors regulating morphogenesis in Candida albicans and independently limits morphogenesis-induced ROS accumulation

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18 May 2017
publication

Selective BET bromodomain inhibition as an antifungal therapeutic strategy

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08 Feb 2017
publication

The intraspecies diversity of C. albicans triggers qualitatively and temporally distinct host responses that determine the balance between commensalism and pathogenicity

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11 Oct 2016
publication

Analysis of Repair Mechanisms following an Induced Double-Strand Break Uncovers Recessive Deleterious Alleles in the Candida albicans Diploid Genome

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23 Sep 2016
publication

Administration of Zinc Chelators Improves Survival of Mice Infected with Aspergillus fumigatus both in Monotherapy and in Combination with Caspofungin

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11 Jul 2016
publication

Administration of zinc chelators improves survival of mice infected with Aspergillus fumigatus both in monotherapy and in combination with caspofungin.

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16 Jun 2016
publication

Prospective Evaluation of Serum β-Glucan Testing in Patients With Probable or Proven Fungal Diseases

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29 Mar 2016
publication

Mechanisms Underlying the Delayed Activation of the Cap1 Transcription Factor in Candida albicans following Combinatorial Oxidative and Cationic Stress Important for Phagocytic Potency

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29 Mar 2016
publication

Pleiotropic effects of the vacuolar ABC transporter MLT1 of Candida albicans on cell function and virulence

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05 Feb 2016
publication

Comparison of E,E-Farnesol Secretion and the Clinical Characteristics of Candida albicans Bloodstream Isolates from Different Multilocus Sequence Typing Clades

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16 Dec 2015
publication

Biofilm formation in Candida glabrata: What have we learnt from functional genomics approaches?

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14 Dec 2015
publication

The Toxicity of a Novel Antifungal Compound Is Modulated by Endoplasmic Reticulum-Associated Protein Degradation Components

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08 Oct 2015
team

Tech Lab

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06 Sep 2015
publication

Candida albicans commensalism in the gastrointestinal tract

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02 Sep 2015
project

Candida albicans genomic diversity and its underlying mechanisms

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02 Sep 2015
project

Candida albicans colonization of abiotic and biotic surfaces

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02 Sep 2015
project

Regulation of Candida albicans morphogenesis

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01 Sep 2015
project

FunComPath

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01 Sep 2015
project

CANDIHUB

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04 Aug 2015
publication

Candida albicans is able to use M cells as a portal of entry across the intestinal barrier in vitro

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11 May 2015
team

Fungal Biology and Pathogenicity

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15 Apr 2015
publication

A single nucleotide polymorphism uncovers a novel function for the transcription factor Ace2 during Candida albicans hyphal development

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18 Mar 2015
team

Biomics

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18 Mar 2015
publication

Of mice, flies–and men? Comparing fungal infection models for large-scale screening efforts

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16 Jan 2015
publication

A FACS-optimized screen identifies regulators of genome stability in Candida albicans

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11 Dec 2014
publication

Targeted changes of the cell wall proteome influence Candida albicans ability to form single- and multi-strain biofilms

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04 Dec 2014
publication

Microevolution of Candida albicans in macrophages restores filamentation in a nonfilamentous mutant

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30 Oct 2014
publication

One small step for a yeast–microevolution within macrophages renders Candida glabrata hypervirulent due to a single point mutation

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08 Oct 2014
publication

Name changes in medically important fungi and their implications for clinical practice

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24 Aug 2014
publication

Genetic diversity among Candida albicans isolates associated with vertical transmission in preterm triplets

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01 Aug 2014
publication

Multilocus sequence typing for the analysis of clonality among Candida albicans strains from a neonatal intensive care unit

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19 Jun 2014
publication

Systematic phenotyping of a large-scale Candida glabrata deletion collection reveals novel antifungal tolerance genes

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25 Dec 2013
publication

A study of the DNA damage checkpoint in Candida albicans: uncoupling of the functions of Rad53 in DNA repair, cell cycle regulation and genotoxic stress-induced polarized growth

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05 Dec 2013
publication

Rbt1 protein domains analysis in Candida albicans brings insights into hyphal surface modifications and Rbt1 potential role during adhesion and biofilm formation

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11 Sep 2013
publication

Gymnemic acids inhibit hyphal growth and virulence in Candida albicans

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15 Aug 2013
publication

A comprehensive functional portrait of two heat shock factor-type transcriptional regulators involved in Candida albicans morphogenesis and virulence

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31 Jul 2013
publication

Candida albicans is not always the preferential yeast colonizing humans: a study in Wayampi Amerindians

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30 Apr 2013
publication

Antifungal activity of fused Mannich ketones triggers an oxidative stress response and is Cap1-dependent in Candida albicans

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06 Apr 2013
publication

Candida albicans biofilms: building a heterogeneous, drug-tolerant environment

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18 Mar 2013
publication

SUN proteins belong to a novel family of β-(1,3)-glucan-modifying enzymes involved in fungal morphogenesis

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01 Feb 2013
publication

Synergy of the antibiotic colistin with echinocandin antifungals in Candida species

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18 Jan 2013
publication

A novel bioluminescence mouse model for monitoring oropharyngeal candidiasis in mice

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25 Sep 2012
publication

A versatile overexpression strategy in the pathogenic yeast Candida albicans: identification of regulators of morphogenesis and fitness

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17 Aug 2012
publication

Using a Multi-Locus Microsatellite Typing method improved phylogenetic distribution of Candida albicans isolates but failed to demonstrate association of some genotype with the commensal or clinical origin of the isolates

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10 May 2012
publication

The NDR/LATS kinase Cbk1 controls the activity of the transcriptional regulator Bcr1 during biofilm formation in Candida albicans

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03 Mar 2012
publication

New regulators of biofilm development in Candida glabrata

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01 Jan 2012
publication

Modular gene over-expression strategies for Candida albicans

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01 Jan 2012
publication

A luciferase reporter for gene expression studies and dynamic imaging of superficial Candida albicans infections

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01 Jan 2012
publication

Biofilm formation studies in microtiter plate format

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01 Jan 2012
publication

Shedding natural light on fungal infections

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01 Aug 2011
publication

Endocytosis-mediated vacuolar accumulation of the human ApoE apolipoprotein-derived ApoEdpL-W antimicrobial peptide contributes to its antifungal activity in Candida albicans

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27 Jul 2011
publication

Th17 cells and IL-17 in protective immunity to vaginal candidiasis

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11 May 2011
publication

Genetic diversity among Korean Candida albicans bloodstream isolates: assessment by multilocus sequence typing and restriction endonuclease analysis of genomic DNA by use of BssHII

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06 Apr 2011
publication

Contribution of the glycolytic flux and hypoxia adaptation to efficient biofilm formation by Candida albicans

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10 Feb 2011
publication

Ultraviolet-C light for treatment of Candida albicans burn infection in mice

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01 May 2010
publication

Bioluminescent fungi for real-time monitoring of fungal infections

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01 Mar 2010
publication

Interaction of Candida albicans biofilms with antifungals: transcriptional response and binding of antifungals to beta-glucans

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22 Jan 2010
publication

The transposon impala is activated by low temperatures: use of a controlled transposition system to identify genes critical for viability of Aspergillus fumigatus

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25 Dec 2009
publication

A beta-glucan-conjugate vaccine and anti-beta-glucan antibodies are effective against murine vaginal candidiasis as assessed by a novel in vivo imaging technique

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18 Dec 2009
publication

Comparative transcript profiling of Candida albicans and Candida dubliniensis identifies SFL2, a C. albicans gene required for virulence in a reconstituted epithelial infection model

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14 Dec 2009
publication

Candida glabrata persistence in mice does not depend on host immunosuppression and is unaffected by fungal amino acid auxotrophy

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01 Sep 2009
publication

Genetic differences between avian and human isolates of Candida dubliniensis

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17 Aug 2009
publication

A multifunctional, synthetic Gaussia princeps luciferase reporter for live imaging of Candida albicans infections

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21 Jun 2009
publication

Hidden killers: persistence of opportunistic fungal pathogens in the human host

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21 Apr 2009
publication

The GPI-modified proteins Pga59 and Pga62 of Candida albicans are required for cell wall integrity

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31 Mar 2009
publication

Candida albicans internalization by host cells is mediated by a clathrin-dependent mechanism

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16 Jan 2009
publication

Correlation between biofilm formation and the hypoxic response in Candida parapsilosis

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21 Dec 2008
publication

Loss of heterozygosity in commensal isolates of the asexual diploid yeast Candida albicans

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17 Jun 2008
publication

Multilocus sequence typing of Candida albicans isolates from animals

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05 Mar 2008
publication

The Yak1 kinase is involved in the initiation and maintenance of hyphal growth in Candida albicans

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05 Dec 2007
publication

Multilocus sequence typing reveals that the population structure of Candida dubliniensis is significantly less divergent than that of Candida albicans

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01 Dec 2007
publication

The SUN41 and SUN42 genes are essential for cell separation in Candida albicans

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26 Nov 2007
publication

CandidaDB: a multi-genome database for Candida species and related Saccharomycotina

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23 Oct 2007
publication

Mating is rare within as well as between clades of the human pathogen Candida albicans

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02 Oct 2007
publication

Candidemia and candiduria in critically ill patients admitted to intensive care units in France: incidence, molecular diversity, management and outcome

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10 Aug 2007
publication

Genotypic evolution of azole resistance mechanisms in sequential Candida albicans isolates

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06 Apr 2007
publication

Molecular phylogenetics of Candida albicans

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28 Jan 2007
publication

Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88

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01 Oct 2006
publication

Protein O-mannosyltransferase isoforms regulate biofilm formation in Candida albicans

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01 May 2006
publication

Multilocus sequence typing reveals intrafamilial transmission and microevolutions of Candida albicans isolates from the human digestive tract

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01 Apr 2006
publication

Biofilms and their role in the resistance of pathogenic Candida to antifungal agents

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20 Mar 2006
publication

G-protein and cAMP-mediated signaling in aspergilli: a genomic perspective

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22 Dec 2005
publication

Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae

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01 Aug 2005
publication

Phosphatidylinositol-dependent phospholipases C Plc2 and Plc3 of Candida albicans are dispensable for morphogenesis and host-pathogen interaction

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17 Jun 2005
publication

A human-curated annotation of the Candida albicans genome

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08 Jun 2005
publication

The heterotrimeric G-protein GanB(alpha)-SfaD(beta)-GpgA(gamma) is a carbon source sensor involved in early cAMP-dependent germination in Aspergillus nidulans

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01 Feb 2005
publication

The Yak1p kinase controls expression of adhesins and biofilm formation in Candida glabrata in a Sir4p-dependent pathway

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01 Jan 2005
publication

CandidaDB: a genome database for Candida albicans pathogenomics

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01 Sep 2004
publication

Multilocus sequence typing of Candida albicans: strategies, data exchange and applications

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01 Apr 2004
publication

Candida albicans biofilms: a developmental state associated with specific and stable gene expression patterns

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01 Nov 2003
publication

Collaborative consensus for optimized multilocus sequence typing of Candida albicans

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01 Jul 2003
publication

Glycerol dehydrogenase, encoded by gldB is essential for osmotolerance in Aspergillus nidulans

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01 Apr 2003
publication

Identification of essential genes in the human fungal pathogen Aspergillus fumigatus by transposon mutagenesis

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01 Mar 2003
publication

Stage-specific gene expression of Candida albicans in human blood

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01 Oct 2002
publication

Identifying essential genes in fungal pathogens of humans

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01 Jul 2002
publication

Characterization of essential genes by parasexual genetics in the human fungal pathogen Aspergillus fumigatus: impact of genomic rearrangements associated with electroporation of DNA

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01 May 2002
publication

cAMP and ras signalling independently control spore germination in the filamentous fungus Aspergillus nidulans

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01 Apr 2002
publication

Usefulness of multilocus sequence typing for characterization of clinical isolates of Candida albicans

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01 Nov 2001
publication

Transcript profiling in Candida albicans reveals new cellular functions for the transcriptional repressors CaTup1, CaMig1 and CaNrg1

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01 Sep 2001
publication

NRG1 represses yeast-hypha morphogenesis and hypha-specific gene expression in Candida albicans

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01 Jul 2001
publication

Trehalose is required for the acquisition of tolerance to a variety of stresses in the filamentous fungus Aspergillus nidulans

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