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© Research
Publication : FEMS yeast research

Candida albicans commensalism in the gastrointestinal tract

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in FEMS yeast research - 06 Sep 2015

Neville BA, d'Enfert C, Bougnoux ME

Link to Pubmed [PMID] – 26347504

FEMS Yeast Res. 2015 Sep;

Candida albicans is a polymorphic yeast species that often forms part of the commensal gastrointestinal mycobiota of healthy humans. It is also an important opportunistic pathogen. A tripartite interaction involving Candida albicans, the resident microbiota and host immunity maintains C. albicans in its commensal form. The influence of each of these factors on C. albicans carriage is considered herein, with particular focus on the mycobiota and the approaches used to study it, models of gastrointestinal colonisation by C. albicans, the C. albicans genes and phenotypes that are necessary for commensalism and the host factors that influence C. albicans carriage.