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© Research
Publication : The Journal of antimicrobial chemotherapy

Large-scale genome mining allows identification of neutral polymorphisms and novel resistance mutations in genes involved in Candida albicans resistance to azoles and echinocandins

Team: Expertise group: Genomics
Team: Bioinformatics and Biostatistics HUB
Member: Thomas Obadia
Member: Corinne Maufrais
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in The Journal of antimicrobial chemotherapy - 10 Jan 2020

Sitterlé E, Coste AT, Obadia T, Maufrais C, Chauvel M, Sertour N, Sanglard D, Puel A, D'Enfert C, Bougnoux ME

Link to Pubmed [PMID] – 31923309

J. Antimicrob. Chemother. 2020 Jan;

The genome of Candida albicans displays significant polymorphism. Point mutations in genes involved in resistance to antifungals may either confer phenotypic resistance or be devoid of phenotypic consequences.

https://www.ncbi.nlm.nih.gov/pubmed/31923309