Ligne de temps
Christophe D’Enfert
Responsable de Structure
11 avr. 2024
publication
A gain-of-function mutation in zinc cluster transcription factor Rob1 Drives Candida albicans adaptive growth in the cystic fibrosis lung environment.
Lire plus01 déc. 2023
publication
Unveiling Candida albicans intestinal carriage in healthy volunteers: the role of micro- and mycobiota, diet, host genetics and immune response.
Lire plus19 sept. 2023
17 mai 2023
25 janv. 2023
publication
The Pga59 cell wall protein is an amyloid forming protein involved in adhesion and biofilm establishment in the pathogenic yeast Candida albicans.
Lire plus12 sept. 2022
publication
Bending stiffness of Candida albicans hyphae as a proxy of cell wall properties.
Lire plus23 juil. 2022
publication
A phylogenetically-restricted essential cell cycle progression factor in the human pathogen Candida albicans.
Lire plus19 juil. 2022
publication
Spatiotemporal dynamics of calcium signals during neutrophil cluster formation.
Lire plus01 juil. 2022
publication
A protocol for ultrastructural study of Candida albicans biofilm using transmission electron microscopy.
Lire plus21 juin 2022
publication
Multiple Stochastic Parameters Influence Genome Dynamics in a Heterozygous Diploid Eukaryotic Model.
Lire plus01 janv. 2022
publication
Functional Portrait of Irf1 (Orf19.217), a Regulator of Morphogenesis and Iron Homeostasis in Candida albicans.
Lire plus26 août 2021
01 avr. 2021
publication
Regulators of commensal and pathogenic life-styles of an opportunistic fungus-Candida albicans.
Lire plus27 mars 2021
18 mars 2021
10 mars 2021
publication
Factors that influence bidirectional long-tract homozygosis due to double-strand break repair in Candida albicans.
Lire plus27 janv. 2021
publication
Involvement of amyloid proteins in the formation of biofilms in the pathogenic yeast Candida albicans.
Lire plus04 déc. 2020
publication
A conserved regulator controls asexual sporulation in the fungal pathogen Candida albicans.
Lire plus24 nov. 2020
publication
The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives.
Lire plus02 sept. 2020
publication
Use of CRISPR-Cas9 To Target Homologous Recombination Limits Transformation-Induced Genomic Changes in Candida albicans.
Lire plus01 juil. 2020
publication
Candida albicans and Candida dubliniensis Show Different Trailing Effect Patterns When Exposed to Echinocandins and Azoles.
Lire plus01 avr. 2020
publication
Large-scale genome mining allows identification of neutral polymorphisms and novel resistance mutations in genes involved in Candida albicans resistance to azoles and echinocandins.
Lire plus01 avr. 2020
31 janv. 2020
01 janv. 2020
publication
Identification and Characterization of Mediators of Fluconazole Tolerance in Candida albicans.
Lire plus09 août 2019
publication
The Candida albicans biofilm gene circuit modulated at the chromatin level by a recent molecular histone innovation
Lire plus29 juil. 2019
event
Candida albicans invasion into epithelial layers: Integrating dynamics, structure and function at the pathogen-host interface- Allon Weiner
Lire plus04 juin 2019
25 avr. 2019
25 avr. 2019
publication
Studying fungal pathogens of humans and fungal infections: fungal diversity and diversity of approaches
Lire plus15 mars 2019
event
Genetic and Epigenetic Mechanisms Driving Phenotypic Diversity in Pathogenic Candida Species – Richard Bennett
Lire plus14 mars 2019
28 févr. 2019
publication
Candida albicans: An Emerging Yeast Model to Study Eukaryotic Genome Plasticity
Lire plus22 févr. 2019
13 févr. 2019
publication
Identification of Recessive Lethal Alleles in the Diploid Genome of a Candida albicans Laboratory Strain Unveils a Potential Role of Repetitive Sequences in Buffering Their Deleterious Impact
Lire plus07 janv. 2019
event
Mini-symposium: Kick-off meeting of the FunHoMic Marie Curie Innovative Training Network – Deciphering the fungus-host-microbiota interplay to improve the management of fungal infections
Lire plus07 janv. 2019
project
FunHoMic MC-ITN: Deciphering the fungus-host-microbiota interplay to improve the management of fungal infections
Lire plus01 janv. 2019
publication
From Genes to Networks: The Regulatory Circuitry Controlling Candida albicans Morphogenesis.
Lire plus14 déc. 2018
event
“Understanding antifungal drug resistance and tolerance in fungal pathogens : impact of genomics” Dominique Sanglard
Lire plus02 nov. 2018
01 nov. 2018
publication
Systematic gene overexpression in Candida albicans identifies a regulator of early adaptation to the mammalian gut.
Lire plus07 sept. 2018
event
Phd Thesis defense “La Candidose cutanéo-muqueuse chronique : un modèle d’étude de l’adaptation génomique chez C.albicans “
Lire plus22 août 2018
21 août 2018
03 août 2018
publication
Combined bacterial and fungal intestinal microbiota analyses: Impact of storage conditions and DNA extraction protocols
Lire plus03 juil. 2018
14 juin 2018
publication
Methodologies for and evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms
Lire plus08 juin 2018
publication
Gene flow contributes to diversification of the major fungal pathogen Candida albicans
Lire plus07 févr. 2018
event
“Candida albicans centromere biology” by Kaustuv SANYAL – Mycology Department Seminar
Lire plus20 nov. 2017
publication
Azole resistance in a mutant lacking the ABC transporter depends on TOR signaling
Lire plus16 nov. 2017
28 juil. 2017
publication
The two-component response regulator Skn7 belongs to a network of transcription factors regulating morphogenesis in Candida albicans and independently limits morphogenesis-induced ROS accumulation.
Lire plus18 mai 2017
08 févr. 2017
publication
The intraspecies diversity of C. albicans triggers qualitatively and temporally distinct host responses that determine the balance between commensalism and pathogenicity
Lire plus11 oct. 2016
publication
Analysis of Repair Mechanisms following an Induced Double-Strand Break Uncovers Recessive Deleterious Alleles in the Candida albicans Diploid Genome
Lire plus11 juil. 2016
publication
Administration of zinc chelators improves survival of mice infected with Aspergillus fumigatus both in monotherapy and in combination with caspofungin.
Lire plus16 juin 2016
publication
Prospective Evaluation of Serum β-Glucan Testing in Patients With Probable or Proven Fungal Diseases
Lire plus29 mars 2016
publication
Mechanisms Underlying the Delayed Activation of the Cap1 Transcription Factor in Candida albicans following Combinatorial Oxidative and Cationic Stress Important for Phagocytic Potency.
Lire plus29 mars 2016
publication
Pleiotropic effects of the vacuolar ABC transporter MLT1 of Candida albicans on cell function and virulence
Lire plus05 févr. 2016
publication
Comparison of E,E-Farnesol Secretion and the Clinical Characteristics of Candida albicans Bloodstream Isolates from Different Multilocus Sequence Typing Clades
Lire plus16 déc. 2015
publication
Biofilm formation in Candida glabrata: What have we learnt from functional genomics approaches?
Lire plus06 sept. 2015
02 sept. 2015
02 sept. 2015
02 sept. 2015
01 sept. 2015
01 sept. 2015
04 août 2015
publication
Candida albicans is able to use M cells as a portal of entry across the intestinal barrier in vitro
Lire plus11 mai 2015
15 avr. 2015
publication
A single nucleotide polymorphism uncovers a novel function for the transcription factor Ace2 during Candida albicans hyphal development
Lire plus18 mars 2015
18 mars 2015
publication
Of mice, flies–and men? Comparing fungal infection models for large-scale screening efforts
Lire plus16 janv. 2015
publication
A FACS-optimized screen identifies regulators of genome stability in Candida albicans
Lire plus04 déc. 2014
publication
Microevolution of Candida albicans in macrophages restores filamentation in a nonfilamentous mutant
Lire plus30 oct. 2014
publication
One small step for a yeast–microevolution within macrophages renders Candida glabrata hypervirulent due to a single point mutation
Lire plus08 oct. 2014
publication
Name changes in medically important fungi and their implications for clinical practice
Lire plus24 août 2014
publication
Genetic diversity among Candida albicans isolates associated with vertical transmission in preterm triplets
Lire plus01 août 2014
publication
Multilocus sequence typing for the analysis of clonality among Candida albicans strains from a neonatal intensive care unit
Lire plus19 juin 2014
publication
Systematic phenotyping of a large-scale Candida glabrata deletion collection reveals novel antifungal tolerance genes
Lire plus25 déc. 2013
publication
A study of the DNA damage checkpoint in Candida albicans: uncoupling of the functions of Rad53 in DNA repair, cell cycle regulation and genotoxic stress-induced polarized growth
Lire plus05 déc. 2013
publication
Rbt1 protein domains analysis in Candida albicans brings insights into hyphal surface modifications and Rbt1 potential role during adhesion and biofilm formation
Lire plus11 sept. 2013
15 août 2013
publication
A comprehensive functional portrait of two heat shock factor-type transcriptional regulators involved in Candida albicans morphogenesis and virulence.
Lire plus31 juil. 2013
publication
Candida albicans is not always the preferential yeast colonizing humans: a study in Wayampi Amerindians
Lire plus30 avr. 2013
publication
Antifungal activity of fused Mannich ketones triggers an oxidative stress response and is Cap1-dependent in Candida albicans
Lire plus06 avr. 2013
publication
Candida albicans biofilms: building a heterogeneous, drug-tolerant environment
Lire plus18 mars 2013
publication
SUN proteins belong to a novel family of β-(1,3)-glucan-modifying enzymes involved in fungal morphogenesis
Lire plus01 févr. 2013
publication
Synergy of the antibiotic colistin with echinocandin antifungals in Candida species
Lire plus18 janv. 2013
publication
A novel bioluminescence mouse model for monitoring oropharyngeal candidiasis in mice
Lire plus17 août 2012
publication
Using a Multi-Locus Microsatellite Typing method improved phylogenetic distribution of Candida albicans isolates but failed to demonstrate association of some genotype with the commensal or clinical origin of the isolates
Lire plus10 mai 2012
publication
The NDR/LATS kinase Cbk1 controls the activity of the transcriptional regulator Bcr1 during biofilm formation in Candida albicans
Lire plus03 mars 2012
01 janv. 2012
publication
A luciferase reporter for gene expression studies and dynamic imaging of superficial Candida albicans infections.
Lire plus01 janv. 2012
01 janv. 2012
01 janv. 2012
01 août 2011
publication
Endocytosis-mediated vacuolar accumulation of the human ApoE apolipoprotein-derived ApoEdpL-W antimicrobial peptide contributes to its antifungal activity in Candida albicans
Lire plus27 juil. 2011
11 mai 2011
publication
Genetic diversity among Korean Candida albicans bloodstream isolates: assessment by multilocus sequence typing and restriction endonuclease analysis of genomic DNA by use of BssHII
Lire plus06 avr. 2011
publication
Contribution of the glycolytic flux and hypoxia adaptation to efficient biofilm formation by Candida albicans
Lire plus10 févr. 2011
01 mai 2010
01 mars 2010
publication
Interaction of Candida albicans biofilms with antifungals: transcriptional response and binding of antifungals to beta-glucans
Lire plus22 janv. 2010
publication
The transposon impala is activated by low temperatures: use of a controlled transposition system to identify genes critical for viability of Aspergillus fumigatus
Lire plus25 déc. 2009
publication
A beta-glucan-conjugate vaccine and anti-beta-glucan antibodies are effective against murine vaginal candidiasis as assessed by a novel in vivo imaging technique
Lire plus18 déc. 2009
publication
Comparative transcript profiling of Candida albicans and Candida dubliniensis identifies SFL2, a C. albicans gene required for virulence in a reconstituted epithelial infection model
Lire plus14 déc. 2009
publication
Candida glabrata persistence in mice does not depend on host immunosuppression and is unaffected by fungal amino acid auxotrophy
Lire plus01 sept. 2009
17 août 2009
publication
A multifunctional, synthetic Gaussia princeps luciferase reporter for live imaging of Candida albicans infections
Lire plus21 juin 2009
publication
Hidden killers: persistence of opportunistic fungal pathogens in the human host
Lire plus21 avr. 2009
publication
The GPI-modified proteins Pga59 and Pga62 of Candida albicans are required for cell wall integrity
Lire plus31 mars 2009
publication
Candida albicans internalization by host cells is mediated by a clathrin-dependent mechanism
Lire plus16 janv. 2009
publication
Correlation between biofilm formation and the hypoxic response in Candida parapsilosis
Lire plus21 déc. 2008
publication
Loss of heterozygosity in commensal isolates of the asexual diploid yeast Candida albicans
Lire plus17 juin 2008
05 déc. 2007
publication
Multilocus sequence typing reveals that the population structure of Candida dubliniensis is significantly less divergent than that of Candida albicans
Lire plus01 déc. 2007
publication
The SUN41 and SUN42 genes are essential for cell separation in Candida albicans
Lire plus26 nov. 2007
publication
CandidaDB: a multi-genome database for Candida species and related Saccharomycotina
Lire plus23 oct. 2007
publication
Mating is rare within as well as between clades of the human pathogen Candida albicans
Lire plus02 oct. 2007
publication
Candidemia and candiduria in critically ill patients admitted to intensive care units in France: incidence, molecular diversity, management and outcome
Lire plus10 août 2007
publication
Genotypic evolution of azole resistance mechanisms in sequential Candida albicans isolates
Lire plus06 avr. 2007
28 janv. 2007
publication
Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88
Lire plus01 oct. 2006
publication
Protein O-mannosyltransferase isoforms regulate biofilm formation in Candida albicans
Lire plus01 mai 2006
publication
Multilocus sequence typing reveals intrafamilial transmission and microevolutions of Candida albicans isolates from the human digestive tract
Lire plus01 avr. 2006
publication
Biofilms and their role in the resistance of pathogenic Candida to antifungal agents
Lire plus20 mars 2006
22 déc. 2005
publication
Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae
Lire plus01 août 2005
publication
Phosphatidylinositol-dependent phospholipases C Plc2 and Plc3 of Candida albicans are dispensable for morphogenesis and host-pathogen interaction
Lire plus17 juin 2005
08 juin 2005
publication
The heterotrimeric G-protein GanB(alpha)-SfaD(beta)-GpgA(gamma) is a carbon source sensor involved in early cAMP-dependent germination in Aspergillus nidulans
Lire plus01 févr. 2005
publication
The Yak1p kinase controls expression of adhesins and biofilm formation in Candida glabrata in a Sir4p-dependent pathway
Lire plus01 janv. 2005
01 sept. 2004
publication
Multilocus sequence typing of Candida albicans: strategies, data exchange and applications
Lire plus01 avr. 2004
publication
Candida albicans biofilms: a developmental state associated with specific and stable gene expression patterns
Lire plus01 nov. 2003
publication
Collaborative consensus for optimized multilocus sequence typing of Candida albicans
Lire plus01 juil. 2003
publication
Glycerol dehydrogenase, encoded by gldB is essential for osmotolerance in Aspergillus nidulans
Lire plus01 avr. 2003
publication
Identification of essential genes in the human fungal pathogen Aspergillus fumigatus by transposon mutagenesis
Lire plus01 mars 2003
01 oct. 2002
01 juil. 2002
publication
Characterization of essential genes by parasexual genetics in the human fungal pathogen Aspergillus fumigatus: impact of genomic rearrangements associated with electroporation of DNA
Lire plus01 mai 2002
publication
cAMP and ras signalling independently control spore germination in the filamentous fungus Aspergillus nidulans
Lire plus01 avr. 2002
publication
Usefulness of multilocus sequence typing for characterization of clinical isolates of Candida albicans
Lire plus01 nov. 2001
publication
Transcript profiling in Candida albicans reveals new cellular functions for the transcriptional repressors CaTup1, CaMig1 and CaNrg1
Lire plus01 sept. 2001
publication
NRG1 represses yeast-hypha morphogenesis and hypha-specific gene expression in Candida albicans
Lire plus01 juil. 2001
publication