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© Research
Event

“Understanding antifungal drug resistance and tolerance in fungal pathogens : impact of genomics” Dominique Sanglard

Scientific Fields
Diseases
Organisms
Applications
Technique
Date
09
Jan 2019
Time
13:30:00
Institut Pasteur, Rue du Docteur Roux, Paris, France
Address
Building: Fernbach RDC Room: Salle Jean Paul Aubert
Location
2019-01-09 13:30:00 2019-01-09 14:30:00 Europe/Paris “Understanding antifungal drug resistance and tolerance in fungal pathogens : impact of genomics” Dominique Sanglard Dominique Sanglard  – Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland Antifungal treatments in patients expose fungal pathogens to repeated contacts with antifungal agents. Under such selection pressures, the pathogens evolve several resistance mechanisms that are […] Institut Pasteur, Rue du Docteur Roux, Paris, France Christophe D’Enfert christophe.denfert@pasteur.fr

About

Dominique Sanglard  – Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland

Antifungal treatments in patients expose fungal pathogens to repeated contacts with antifungal agents. Under such selection pressures, the pathogens evolve several resistance mechanisms that are necessary for survival in the host. In this presentation, antifungal resistance development will be discussed in several Candida species. Another phenomenon linked to the adaptation of fungal pathogens to antifungal drugs is known as antifungal tolerance. Since antifungal tolerance may have an impact on drug efficacy, it became relevant to understand the associated mechanisms. Understanding of both drug resistance and drug tolerance mechanisms is greatly facilitated by genomic approaches.

Contact : Christophe D’Enfert (christophe.denfert@pasteur.fr)

Location

Building: Fernbach RDC
Room: Salle Jean Paul Aubert
Address: Institut Pasteur, Rue du Docteur Roux, Paris, France