About

The scientists, engineers, students and postdoctoral fellows in the Structural Biology and Chemistry Department study complex biological systems through a range of integrated approaches. We use observational techniques, experimentation and cutting-edge tools to gain insight into molecular mechanisms and structure at different scales of investigation down to the minutest detail. Our department has built a strong focus on structural biology through the use of X-ray diffraction, nuclear magnetic resonance and electron cryomicroscopy techniques. Our chemistry research focuses primarily on polysaccharides and nucleic acids. Several teams are also studying molecular interactions and reactions, and their physiological impact at the cellular level, using a variety of biochemical, biophysical and microscopy techniques. In silico simulation and prediction complete the range of approaches taken in the department. Our research relies on advanced core facilities housed within a central hub of technological platforms. The department hosts two joint research units with the CNRS (French National Center for Scientific Research) – UMR 3528 “Structural biology of cellular processes and infectious diseases” and UMR 3523 “Organic Chemistry Unit”.

Events

HDX-MS/NMR DAY

Room: Amphitheater François Jacob – Address: Institut Pasteur, Rue du Docteur Roux, Paris, France
2017-03-16 09:00:00 2017-03-16 18:00:00 Europe/Paris HDX-MS/NMR DAY Dear Colleagues, We are pleased to invite you to attend our upcoming Hydrogen Deuterium eXchange Day (HDX-Day) that will be held at the Institut Pasteur, Paris, on Thursday March 16th 2017. The aim of this […] Institut Pasteur, Rue du Docteur Roux, Paris, France

Antonio Mucherino (IRISA, University of Rennes 1): Dynamical Distance Geometry and Proteins

Building: Lwoff – Room: 014-015 – Address: 28 Rue du Dr Roux, Paris, France
2017-06-22 10:30:00 2017-06-22 13:30:00 Europe/Paris Antonio Mucherino (IRISA, University of Rennes 1): Dynamical Distance Geometry and Proteins Distance Geometry (DG) asks whether an embedding exists for a simple weighted undirected graph G=(V,E,d) such that distances between embedded vertices u and v are the same as the weights d(u,v) in the graph. […] 28 Rue du Dr Roux, Paris, France

Eric Vanden-Eijnden (Courant Institute, New York): Multiscale implementation of infinite-swap replica exchange molecular dynamics

Address: Institut Pasteur, Rue du Docteur Roux, Paris, France
2017-07-05 14:00:00 2017-07-05 15:00:00 Europe/Paris Eric Vanden-Eijnden (Courant Institute, New York): Multiscale implementation of infinite-swap replica exchange molecular dynamics Replica exchange molecular dynamics (REMD) is a popular method to accelerate conformational sampling of complex molecular systems. The idea is to run several replicas of the system in parallel at different temperatures that are […] Institut Pasteur, Rue du Docteur Roux, Paris, France

Dr. Benoit GIGANT – “Motility and microtubule disassembly: two stories about kinesins”

Room: Salle RETROVIRUS - Lwoff RdC 14 – Address: 28 Rue du Docteur Roux, Paris, France
2017-11-28 14:00:00 2017-11-28 19:00:00 Europe/Paris Dr. Benoit GIGANT – “Motility and microtubule disassembly: two stories about kinesins” Séminaire du Département de Biologie Structurale & Chimie Mardi 28 Novembre 2017 à 14h00 Salle RETROVIRUS – Lwoff RdC 14 Dr. Benoit GIGANT Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université […] 28 Rue du Docteur Roux, Paris, France

Prof. Michael BOTT – “Corynebacterium glutamicum – microbial cell factory and model organism for actinobacteria”

Room: Amphithéatre Bâtiment François JACOB – Address: 28 Rue du Docteur Roux, Paris, France
2017-12-15 11:30:00 2017-12-15 19:00:00 Europe/Paris Prof. Michael BOTT – “Corynebacterium glutamicum – microbial cell factory and model organism for actinobacteria” Séminaire Conjoint : Département de Biologie Structurale & Chimie et  Département Microbiologie Vendredi 15 décembre 2017 à 11h30 Amphithéatre Bâtiment François JACOB  Prof. Michael BOTT Director, Institute of Bio- and Geosciences 1 (Biotechnology) Forschungszentrum Jülich, […] 28 Rue du Docteur Roux, Paris, France

Prof. Frank NOE – “From all-atom molecular kinetics beyond the seconds timescale to cellular signal transduction”

Room: Bâtiment RETROVIRUS LWOFF Salle 14-15 – RDC – Address: 28 Rue du Docteur Roux, Paris, France
2017-12-19 14:00:00 2017-12-19 19:00:00 Europe/Paris Prof. Frank NOE – “From all-atom molecular kinetics beyond the seconds timescale to cellular signal transduction” Mardi 19 DECEMBRE 2017 à 14h00 Bâtiment RETROVIRUS LWOFF Salle 14-15 – RDC Prof. Frank NOE Freie Universität Berlin, Department for Mathematics  and Computer Science, Berlin, Germany “From all-atom molecular kinetics beyond the seconds […] 28 Rue du Docteur Roux, Paris, France

Prof. CLEMENTI Cécilia – “Incorporating experimental data in long timescales macromolecular simulations”

Room: Bâtiment RETROVIRUS LWOFF Salle 14-15 – RDC – Address: 25 Rue du Docteur Roux, Paris, France
2017-12-21 14:00:00 2017-12-21 19:00:00 Europe/Paris Prof. CLEMENTI Cécilia – “Incorporating experimental data in long timescales macromolecular simulations” Jeudi 21 Décembre 2017 à 14h00 Bâtiment RETROVIRUS LWOFF Salle 14-15 – RDC    Prof. CLEMENTI Cécilia Rice University, Department of Chemistry and Center for Theoretical Biological Physics   “Incorporating experimental data in long […] 25 Rue du Docteur Roux, Paris, France

Teams

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