About

The scientists, engineers, students and postdoctoral fellows in the Structural Biology and Chemistry Department study complex biological systems through a range of integrated approaches. We use observational techniques, experimentation and cutting-edge tools to gain insight into molecular mechanisms and structure at different scales of investigation down to the minutest detail. Our department has built a strong focus on structural biology through the use of X-ray diffraction, nuclear magnetic resonance and electron cryomicroscopy techniques. Our chemistry research focuses primarily on polysaccharides and nucleic acids. Several teams are also studying molecular interactions and reactions, and their physiological impact at the cellular level, using a variety of biochemical, biophysical and microscopy techniques. In silico simulation and prediction complete the range of approaches taken in the department. Our research relies on advanced core facilities housed within a central hub of technological platforms. The department hosts two joint research units with the CNRS (French National Center for Scientific Research) – UMR 3528 “Structural biology of cellular processes and infectious diseases” and UMR 3523 “Organic Chemistry Unit”.

Events

HDX-MS/NMR DAY

Room: Amphitheater François Jacob – Address: Institut Pasteur, Rue du Docteur Roux, Paris, France
2017-03-16 09:00:00 2017-03-16 18:00:00 Europe/London HDX-MS/NMR DAY Dear Colleagues, We are pleased to invite you to attend our upcoming Hydrogen Deuterium eXchange Day (HDX-Day) that will be held at the Institut Pasteur, Paris, on Thursday March 16th 2017. The aim of this […] Institut Pasteur, Rue du Docteur Roux, Paris, France

Antonio Mucherino (IRISA, University of Rennes 1): Dynamical Distance Geometry and Proteins

Building: Lwoff – Room: 014-015 – Address: 28 Rue du Dr Roux, Paris, France
2017-06-22 10:30:00 2017-06-22 13:30:00 Europe/London Antonio Mucherino (IRISA, University of Rennes 1): Dynamical Distance Geometry and Proteins Distance Geometry (DG) asks whether an embedding exists for a simple weighted undirected graph G=(V,E,d) such that distances between embedded vertices u and v are the same as the weights d(u,v) in the graph. […] 28 Rue du Dr Roux, Paris, France

Eric Vanden-Eijnden (Courant Institute, New York): Multiscale implementation of infinite-swap replica exchange molecular dynamics

Address: Institut Pasteur, Rue du Docteur Roux, Paris, France
2017-07-05 14:00:00 2017-07-05 15:00:00 Europe/London Eric Vanden-Eijnden (Courant Institute, New York): Multiscale implementation of infinite-swap replica exchange molecular dynamics Replica exchange molecular dynamics (REMD) is a popular method to accelerate conformational sampling of complex molecular systems. The idea is to run several replicas of the system in parallel at different temperatures that are […] Institut Pasteur, Rue du Docteur Roux, Paris, France

Dr Peter J. BOND – “Multiscale Simulations Help Map Flavivirus Fusion Dynamics”

Room: Auditorium du Centre F. Jacob – Address: 28 Rue du Docteur Roux, Paris, France
2017-09-07 12:00:00 2017-09-07 19:00:00 Europe/London Dr Peter J. BOND – “Multiscale Simulations Help Map Flavivirus Fusion Dynamics” Séminaire du Département de Biologie Structurale & Chimie   Jeudi 7 Septembre 2017 à 12 h Auditorium du Centre F. Jacob Dr Peter J. BOND Bioinformatics Institute (A*STAR), Matrix 07-01, 30 Biopolis Street, Singapore […] 28 Rue du Docteur Roux, Paris, France

Pr Christian LEUMANN -University of Bern- “A revival of bicyclo-DNA”

Room: Salle JULES BORDET - Metchnikoff RdC 45 – Address: 25 Rue du Dr Roux, Paris, France
2017-09-07 14:00:00 2017-09-07 19:00:00 Europe/London Pr Christian LEUMANN -University of Bern- “A revival of bicyclo-DNA” Séminaire du Département de Biologie Structurale & Chimie   Jeudi 7 Septembre 2017 à 14h00 Salle JULES BORDET – Metchnikoff RdC 45   Pr Christian LEUMANN University of Bern   A revival of bicyclo-DNA […] 25 Rue du Dr Roux, Paris, France

Prof. Jean-Louis REYMOND – “Chemical Space as a Source of Bioactive Small Molecules and Peptides”

Room: Salle RETROVIRUS - Lwoff RdC 14 - – Address: 28 Rue du Docteur Roux, Paris, France
2017-09-26 14:00:00 2017-09-26 19:00:00 Europe/London Prof. Jean-Louis REYMOND – “Chemical Space as a Source of Bioactive Small Molecules and Peptides” Séminaire du Département de Biologie Structurale & Chimie  Mardi 26 Septembre 2017 à 14 h Salle RETROVIRUS – Lwoff RdC 14 – Prof. Jean-Louis REYMOND University of Berne, Switzerland Chemical Space as a Source […] 28 Rue du Docteur Roux, Paris, France

Pr Franca FRATERNALI – “Protein Protein Interactions in Health and Disease”

Room: Salle RETROVIRUS - Lwoff RdC 14 – Address: 28 Rue du Docteur Roux, Paris, France
2017-10-03 14:00:00 2017-10-03 19:00:00 Europe/London Pr Franca FRATERNALI – “Protein Protein Interactions in Health and Disease” Séminaire du Département de Biologie Structurale & Chimie Mardi 3 Octobre 2017 à 14.00 Salle RETROVIRUS – Lwoff RdC 14   Pr Franca FRATERNALI Randall Division of Cellular and Molecular Biophysics, King’s College London, […] 28 Rue du Docteur Roux, Paris, France

Teams

Featured Projects

Featured Publications