About

The scientists, engineers, students and postdoctoral fellows in the Structural Biology and Chemistry Department study complex biological systems through a range of integrated approaches. We use observational techniques, experimentation and cutting-edge tools to gain insight into molecular mechanisms and structure at different scales of investigation down to the minutest detail. Our department has built a strong focus on structural biology through the use of X-ray diffraction, nuclear magnetic resonance and electron cryomicroscopy techniques. Our chemistry research focuses primarily on polysaccharides and nucleic acids. Several teams are also studying molecular interactions and reactions, and their physiological impact at the cellular level, using a variety of biochemical, biophysical and microscopy techniques. In silico simulation and prediction complete the range of approaches taken in the department. Our research relies on advanced core facilities housed within a central hub of technological platforms. The department hosts two joint research units with the CNRS (French National Center for Scientific Research) – UMR 3528 “Structural biology of cellular processes and infectious diseases” and UMR 3523 “Organic Chemistry Unit”.

Events

HDX-MS/NMR DAY

Dear Colleagues, We are pleased to invite you to attend our upcoming Hydrogen Deuterium eXchange Day (HDX-Day) that will be held at the Institut Pasteur, Paris, on Thursday March 16th 2017. The aim of this […]

2017-03-16 09:00:00 2017-03-16 18:00:00 Europe/London HDX-MS/NMR DAY Dear Colleagues, We are pleased to invite you to attend our upcoming Hydrogen Deuterium eXchange Day (HDX-Day) that will be held at the Institut Pasteur, Paris, on Thursday March 16th 2017. The aim of this […] Institut Pasteur, Rue du Docteur Roux, Paris, France

William Clemons seminar

Séminaire du Département de Biologie Structurale & Chimie Lundi 29 mai 2017 à 14h00 Salle LWOFF 14 – RDC 22  Prof. William Clemons Caltech, Pasadena Structural Insights into the Targeting of Tail-Anchored Membrane Proteins […]

2017-05-29 14:00:00 2017-05-29 18:00:00 Europe/London William Clemons seminar Séminaire du Département de Biologie Structurale & Chimie Lundi 29 mai 2017 à 14h00 Salle LWOFF 14 – RDC 22  Prof. William Clemons Caltech, Pasadena Structural Insights into the Targeting of Tail-Anchored Membrane Proteins […] 28 Rue du Dr Roux, Paris, France

“NMR in drug discovery” – Dr Wolfgang JAHNKE

Séminaire du Département de Biologie Structurale & Chimie Dr Wolfgang JAHNKE (Novartis Institutes for Biomedical Research Chemical Biology and Therapeutics, Basel, Switzerland) “NMR in drug discovery” NMR spectroscopy not only is a powerful method […]

2017-06-20 11:00:00 2017-06-20 00:00:00 Europe/London “NMR in drug discovery” – Dr Wolfgang JAHNKE Séminaire du Département de Biologie Structurale & Chimie Dr Wolfgang JAHNKE (Novartis Institutes for Biomedical Research Chemical Biology and Therapeutics, Basel, Switzerland) “NMR in drug discovery” NMR spectroscopy not only is a powerful method […] 25 Rue du Docteur Roux, Paris, France

Antonio Mucherino (IRISA, University of Rennes 1): Dynamical Distance Geometry and Proteins

Distance Geometry (DG) asks whether an embedding exists for a simple weighted undirected graph G=(V,E,d) such that distances between embedded vertices u and v are the same as the weights d(u,v) in the graph. […]

2017-06-22 10:30:00 2017-06-22 13:30:00 Europe/London Antonio Mucherino (IRISA, University of Rennes 1): Dynamical Distance Geometry and Proteins Distance Geometry (DG) asks whether an embedding exists for a simple weighted undirected graph G=(V,E,d) such that distances between embedded vertices u and v are the same as the weights d(u,v) in the graph. […] 28 Rue du Dr Roux, Paris, France

Carlile Lavor (UNICAMP, Brazil): Distance Geometry and Conformal Clifford Algebra

In this talk, we will explain how Conformal Clifford Algebra can be used to model “interval distances” from NMR experiments in order to combine continuous and discrete characteristics of the Molecular Distance Geometry Problem […]

2017-06-22 11:30:00 2017-06-22 00:12:30 Europe/London Carlile Lavor (UNICAMP, Brazil): Distance Geometry and Conformal Clifford Algebra In this talk, we will explain how Conformal Clifford Algebra can be used to model “interval distances” from NMR experiments in order to combine continuous and discrete characteristics of the Molecular Distance Geometry Problem […] 28 Rue du Dr Roux, Paris, France

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