About

The scientists, engineers, students and postdoctoral fellows in the Structural Biology and Chemistry Department study complex biological systems through a range of integrated approaches. We use observational techniques, experimentation and cutting-edge tools to gain insight into molecular mechanisms and structure at different scales of investigation down to the minutest detail. Our department has built a strong focus on structural biology through the use of X-ray diffraction, nuclear magnetic resonance and electron cryomicroscopy techniques. Our chemistry research focuses primarily on polysaccharides and nucleic acids. Several teams are also studying molecular interactions and reactions, and their physiological impact at the cellular level, using a variety of biochemical, biophysical and microscopy techniques. In silico simulation and prediction complete the range of approaches taken in the department. Our research relies on advanced core facilities housed within a central hub of technological platforms. The department hosts two joint research units with the CNRS (French National Center for Scientific Research) – UMR 3528 “Structural biology of cellular processes and infectious diseases” and UMR 3523 “Organic Chemistry Unit”.

Events

HDX-MS/NMR DAY

Room: Amphitheater François Jacob – Address: Institut Pasteur, Rue du Docteur Roux, Paris, France
2017-03-16 09:00:00 2017-03-16 18:00:00 Europe/Paris HDX-MS/NMR DAY Dear Colleagues, We are pleased to invite you to attend our upcoming Hydrogen Deuterium eXchange Day (HDX-Day) that will be held at the Institut Pasteur, Paris, on Thursday March 16th 2017. The aim of this […] Institut Pasteur, Rue du Docteur Roux, Paris, France

Antonio Mucherino (IRISA, University of Rennes 1): Dynamical Distance Geometry and Proteins

Building: Lwoff – Room: 014-015 – Address: 28 Rue du Dr Roux, Paris, France
2017-06-22 10:30:00 2017-06-22 13:30:00 Europe/Paris Antonio Mucherino (IRISA, University of Rennes 1): Dynamical Distance Geometry and Proteins Distance Geometry (DG) asks whether an embedding exists for a simple weighted undirected graph G=(V,E,d) such that distances between embedded vertices u and v are the same as the weights d(u,v) in the graph. […] 28 Rue du Dr Roux, Paris, France

Bisubstrate analogues as N-methyltransferase inhibitors and tool compounds for structural studies – Nathaniel I. Martin Phd

Building: Auditorium Centre J. Jacob – Room: Rdc 17C – Address: 28 Rue du Docteur Roux, 75015 Paris, France
2018-04-03 14:00:00 2018-04-03 19:00:00 Europe/Paris Bisubstrate analogues as N-methyltransferase inhibitors and tool compounds for structural studies – Nathaniel I. Martin Phd Nathaniel I. Martin Phd – Utrecht Institute for Pharmaceutical Sciences, Utrecht University The N-methyltransferases represent a large enzyme family that functions by specifically transferring a methyl group from the cofactor S-adenosyl-l-methionine (AdoMet) to a nitrogen […] 28 Rue du Docteur Roux, 75015 Paris, France

C3BI Seminar : MixMD: Mapping Protein Surfaces to Discover Druggable Allosteric Sites

Building: Centre François Jacob – Room: Auditorium, Rdc – Address: Institut Pasteur, 28 Rue du Docteur Roux, Paris, France
2018-05-17 14:00:00 2018-05-17 15:00:00 Europe/Paris C3BI Seminar : MixMD: Mapping Protein Surfaces to Discover Druggable Allosteric Sites Research in the Carlson lab focuses broadly on the molecular recognition between ligands and proteins, from the fundamental biophysics of ligand binding to applied inhibitor design.  Understanding protein flexibility, allosteric control, and ligand binding […] Institut Pasteur, 28 Rue du Docteur Roux, Paris, France

Transporting cargo over long distances: insights from dynein/dynactin structures – Seminar by Andrew Carter

Building: CFJ – Room: Auditorium Centre Francois Jacob – Address: 28 Rue du Docteur Roux, Paris, France
2018-05-22 14:00:00 2018-05-22 15:00:00 Europe/Paris Transporting cargo over long distances: insights from dynein/dynactin structures – Seminar by Andrew Carter Cells depend on components being moved to the correct place at the correct time. My group is interested in cytoplasmic dynein-1 (dynein), a motor which delivers many different cargos via the microtubule network. When […] 28 Rue du Docteur Roux, Paris, France

Qbio symposium – Physics of Biological Membranes

Building: François Jacob Auditorium – Address: Institut Pasteur, Paris, France
2018-05-25 10:00:00 2018-05-25 17:30:00 Europe/Paris Qbio symposium – Physics of Biological Membranes Institut Pasteur, Paris, France

DNA bases beyond Watson & Crock – Pr. Thomas CARELL

Building: Auditorium Centre F. JACOB – Room: RDC 17C – Address: 28 Rue du Docteur Roux, Paris, France
2018-06-05 14:00:00 2018-06-05 17:00:00 Europe/Paris DNA bases beyond Watson & Crock – Pr. Thomas CARELL Pr. Thomas CARELL – Department für Chemie, LMU Müchen www.carellgroup.de<http://www.carellgroup.de/     28 Rue du Docteur Roux, Paris, France

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