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About

Directeur de Recherche, CNRS

Projects

Project
Ongoing
13 Members

OM-LipAsy

Christophe Beloin (PI)

The outer membrane (OM) is an essential element in Gram-negative (diderm) bacteria. Its integrity is maintained by the control of lipids asymmetry via LPS and phospholipids transport by the Lpt and Mla systems, respectively. […]
Project
Ongoing
6 Members

Synergy_T2SS

Olivera Francetic (PI)

Protein secretion in bacteria is highly specific. Substrates secreted via the Type II secretion nanomachines are fully folded prior to secretion and are specifically recognized in their native state. In some cases, they even […]
Project
Ongoing
9 Members

Protein synthesis machinery of Trypanosomatid as a therapeutic target

Nadia Izadi-Pruneyre (PI)

Pathogenic protozoans of the trypanosomatid group still remain a major world health problem. Cycling between insect vectors and mammalian hosts, Trypanosoma cruzi is the causative agent of Chagas disease, while over 20 Leishmania species […]
Project
Ongoing
3 Members

ViBrANT (Viral and Bacterial Adhesin Network Training)

Michael Nilges (PI)

The Innovative Training Network ViBrANT (Viral and Bacterial Adhesin Network Training) brings together world-leading European scientists to train 15 graduate students (early stage researchers) in interdisciplinary research into viral and bacterial adhesins. ViBrANT is […]
Project
Ongoing
4 Members

Binding mode of promising antituberculosis clinical compounds to their bacterial target

Nadia Izadi-Pruneyre (PI)

New therapeutic strategies are needed to combat the pandemics and the spread of multidrug resistant form of tuberculosis. This collaborative project between our group and Institut Pasteur of Korea aims to decipher the molecular […]
Project
Ongoing
3 Members

FiberSpace

Olivera Francetic (PI)

Type IV pili and pseudopili: structure, dynamics, assembly and molecular function Type IV pili and pseudopili assembled by type 2 secretion systems (T2SS) are thin dynamic fibers that perform diverse functions, from  adherence, motility, […]
Project
Ongoing
7 Members

Bacterial Transmembrane Signaling

Nadia Izadi-Pruneyre (PI)

Bacteria display several mechanisms to adapt to their host-environment and successfully colonise it. One important mechanism of adaptation concerns the regulation of gene expression in response to external signals such as the presence of […]

Publications

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