The structural bioinformatics research group was created in March 2001. Our research focuses on the relationship between sequence, three-dimensional structure, and function of proteins, using, among others, modelling techniques and molecular dynamics simulations. We also continue the development of software for automated NMR structure calculations, and are collaborating with structural genomics projects and the structure databases. We have established collaborations with experimental groups at the Institut Pasteur and elsewhere, for example, in atomic force spectroscopy, X-ray crystallography, and microscopy. The aim of our research is to complement structural studies (X-rays, NMR, Electron microscopy, and others) with in silico studies, to:
- better determine and predict three-dimensional structures
- better understand molecular recognition and molecular interactions.
Our research topics include medically relevant molecular processes (infectious diseases, cancer, and the action of general anesthetics).