Timeline
Ana Cumano
Permanent Researcher
01 Jan 2024
publication
Beyond 40 fluorescent probes for deep phenotyping of blood mononuclear cells, using spectral technology.
Read more01 Jan 2024
publication
Bone marrow monocytes sustain NK cell-poiesis during non-alcoholic steatohepatitis
Read more20 Oct 2023
publication
Multimodal cartography of human lymphopoiesis reveals B and T/NK/ILC lineages are subjected to differential regulation.
Read more04 Sep 2023
25 Aug 2023
publication
Spatiotemporal dynamics of cytokines expression dictate fetal liver hematopoiesis.
Read more08 Jun 2023
publication
Distinct subsets of multi-lymphoid progenitors support ontogeny-related changes in human lymphopoiesis.
Read more03 Mar 2023
publication
Assembling the layers of the hematopoietic system: A window of opportunity for thymopoiesis in the embryo.
Read more20 Jun 2022
publication
Variability of Primary Sjögren’s Syndrome Is Driven by Interferon-α and Interferon-α Blood Levels Are Associated With the Class II HLA-DQ Locus.
Read more02 May 2022
publication
Identification of fetal liver stroma in spectral cytometry using the parameter autofluorescence.
Read more26 Oct 2021
05 Oct 2021
05 Apr 2021
publication
Yolk sac, but not hematopoietic stem cell-derived progenitors, sustain erythropoiesis throughout murine embryonic life.
Read more06 Sep 2020
publication
A wave of bipotent T/ILC-restricted progenitors shapes the embryonic thymus microenvironment in a time-dependent manner.
Read more26 May 2020
publication
Genetic dissection of Rift Valley fever pathogenesis: Rvfs2 locus on mouse chromosome 11 enables survival to early-onset hepatitis.
Read more30 Jan 2020
event
Department of Immunology seminar: Fernando Camargo, Lineage analysis at the single cell level
Read more01 Jan 2020
publication
Crosstalk Between the Hepatic and Hematopoietic Systems During Embryonic Development.
Read more01 Jan 2020
04 Nov 2019
publication
Maintenance of Type 2 Response by CXCR6-Deficient ILC2 in Papain-Induced Lung Inflammation
Read more01 Oct 2019
publication
Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).
Read more19 Sep 2019
27 Jun 2019
publication
Mouse HSA+ immature cardiomyocytes persist in the adult heart and expand after ischemic injury
Read more26 Apr 2019
14 Feb 2019
08 Jan 2019
publication
Mapping structure and biological functions within mesenchymal bodies using microfluidics
Read more21 Sep 2018
27 Jun 2018
07 Jun 2018
publication
The Notch Signaling Pathway Is Balancing Type 1 Innate Lymphoid Cell Immune Functions
Read more04 Jun 2018
10 Apr 2018
publication
Mice with reduced expression of the telomere-associated protein Ft1 develop p53-sensitive progeroid traits
Read more01 Mar 2018
publication
The Dynamics of Interleukin-10-Afforded Protection during Dextran Sulfate Sodium-Induced Colitis
Read more26 Feb 2018
12 Jan 2018
publication
PAXX and Xlf interplay revealed by impaired CNS development and immunodeficiency of double KO mice
Read more17 Oct 2017
publication
Molecular and Functional Characterization of Lymphoid Progenitor Subsets Reveals a Bipartite Architecture of Human Lymphopoiesis
Read more01 Oct 2017
publication
Guidelines for the use of flow cytometry and cell sorting in immunological studies.
Read more21 Aug 2017
publication
Asynchronous lineage priming determines commitment to T cell and B cell lineages in fetal liver
Read more05 May 2017
publication
Analysis of Cell Suspensions Isolated from Solid Tissues by Spectral Flow Cytometry
Read more13 Apr 2017
31 Jan 2017
19 Jan 2017
publication
Single-cell gene expression using multiplex RT-qPCR to characterize heterogeneity of rare lymphoid populations
Read more13 Jan 2017
13 Jan 2017
08 Aug 2016
publication
Spectral Cytometry Has Unique Properties Allowing Multicolor Analysis of Cell Suspensions Isolated from Solid Tissues
Read more20 May 2016
03 May 2016
29 Apr 2016
publication
The cyclin D1 carboxyl regulatory domain controls the division and differentiation of hematopoietic cells
Read more21 Mar 2016
publication
Estrogen-mediated downregulation of AIRE influences sexual dimorphism in autoimmune diseases
Read more18 Jan 2016
publication
Single-Cell Gene Expression Analyses Reveal Heterogeneous Responsiveness of Fetal Innate Lymphoid Progenitors to Notch Signaling
Read more01 Oct 2015
01 Jul 2015
09 Jun 2015
publication
Characterization of Thymic Settling Progenitors in the Mouse Embryo Using In Vivo and In Vitro Assays
Read more01 Jun 2015
publication
Osteoblast-specific expression of the fibrous dysplasia (FD)-causing mutation Gsα(R201C) produces a high bone mass phenotype but does not reproduce FD in the mouse
Read more01 Nov 2014
publication
Constitutive expression of Gsα(R201C) in mice produces a heritable, direct replica of human fibrous dysplasia bone pathology and demonstrates its natural history
Read more14 Jul 2014
25 Jan 2014
08 Dec 2013
publication
Two waves of distinct hematopoietic progenitor cells colonize the fetal thymus
Read more23 Sep 2013
publication
Notchless-dependent ribosome synthesis is required for the maintenance of adult hematopoietic stem cells
Read more13 Sep 2013
05 Aug 2013
01 Apr 2013
publication
A novel murine model of rhinoscleroma identifies Mikulicz cells, the disease signature, as IL-10 dependent derivatives of inflammatory monocytes
Read more03 Jan 2013
publication
GATA-3 promotes T-cell specification by repressing B-cell potential in pro-T cells in mice
Read more12 Sep 2012
publication
Inhibitors of DNA binding proteins restrict T cell potential by repressing Notch1 expression in Flt3-negative common lymphoid progenitors
Read more16 Aug 2012
24 Feb 2012
publication
Myf5 haploinsufficiency reveals distinct cell fate potentials for adult skeletal muscle stem cells
Read more11 Jan 2012
08 Dec 2011
11 Sep 2011
publication
Notch signaling is necessary for adult, but not fetal, development of RORγt(+) innate lymphoid cells
Read more01 Jul 2011
publication
Msx genes define a population of mural cell precursors required for head blood vessel maturation
Read more14 Oct 2010
publication
Sumoylation by Ubc9 regulates the stem cell compartment and structure and function of the intestinal epithelium in mice
Read more16 Apr 2010
13 Mar 2010
publication
Reduced EBF expression underlies loss of B-cell potential of hematopoietic progenitors with age
Read more01 Dec 2009
publication
Pax3:Foxc2 reciprocal repression in the somite modulates muscular versus vascular cell fate choice in multipotent progenitors.
Read more01 Nov 2009
publication
Numb promotes an increase in skeletal muscle progenitor cells in the embryonic somite
Read more11 Aug 2009
publication
Muscle stem cell behavior is modified by microRNA-27 regulation of Pax3 expression.
Read more19 May 2009
publication
Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim sustains B lymphopoiesis in the absence of IL-7
Read more01 May 2009
09 Mar 2009
publication
CX3CR1+ CD115+ CD135+ common macrophage/DC precursors and the role of CX3CR1 in their response to inflammation
Read more21 Jan 2009
12 Nov 2008
publication
Neurotoxic activation of microglia is promoted by a nox1-dependent NADPH oxidase
Read more10 Apr 2008
publication
Separation of splenic red and white pulp occurs before birth in a LTalphabeta-independent manner
Read more01 Mar 2008
01 Mar 2008
12 Feb 2008
publication
Identification of CD4int progenitors in mouse fetal spleen, a source of resident lymphoid cells
Read more01 Aug 2007
publication
Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior
Read more01 Mar 2007
01 Jan 2007
01 Oct 2006
publication
A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127
Read more16 Aug 2006
08 Jun 2006
publication
Ontogeny, function, and peripheral homeostasis of regulatory T cells in the absence of interleukin-7
Read more01 May 2006
publication
Processing of the bovine spongiform encephalopathy-specific prion protein by dendritic cells
Read more25 Jan 2006
02 Jan 2006
publication
Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells.
Read more01 Dec 2005
publication
A clonogenic bone marrow progenitor specific for macrophages and dendritic cells
Read more01 Sep 2005
01 Aug 2005
publication
Numbers of Foxp3-expressing CD4+CD25high T cells do not correlate with the establishment of long-term tolerance after allogeneic stem cell transplantation
Read more14 Jul 2005
14 Mar 2005
publication
Interleukin-7 is necessary to maintain the B cell potential in common lymphoid progenitors
Read more01 Mar 2005
publication
In vivo and in absence of a thymus, the enforced expression of the Notch ligands delta-1 or delta-4 promotes T cell development with specific unique effects
Read more01 Jan 2005
01 Jan 2005
27 Dec 2004
publication
Characterization of purified intraembryonic hematopoietic stem cells as a tool to define their site of origin
Read more14 Oct 2004
publication
The notch ligand Delta1 recruits Dlg1 at cell-cell contacts and regulates cell migration
Read more27 Sep 2004
19 Jul 2004
publication
Pre-B cell receptor expression is necessary for thymic stromal lymphopoietin responsiveness in the bone marrow but not in the liver environment
Read more25 Jan 2004
01 Jan 2004
09 Dec 2003
publication
IkappaBalpha/IkappaBepsilon deficiency reveals that a critical NF-kappaB dosage is required for lymphocyte survival
Read more19 Nov 2003
publication
Primordial hematopoietic stem cells generate microglia but not myelin-forming cells in a neural environment
Read more20 Jul 2003
publication
Thymic stromal-derived lymphopoietin distinguishes fetal from adult B cell development
Read more31 Mar 2003
01 Feb 2003
publication
The repertoires of circulating human CD8(+) central and effector memory T cell subsets are largely distinct
Read more01 Dec 2002
01 Aug 2002
15 Jan 2002
publication
Identification of the earliest prethymic bipotent T/NK progenitor in murine fetal liver
Read more01 Jan 2002
publication
Deoxyguanosine blocks allograft rejection of thymic epithelium but not lymphocyte infiltration and recognition
Read more01 Nov 2001
publication
Embryonic thymic epithelium naturally devoid of APCs is acutely rejected in the absence of indirect recognition
Read more15 Oct 2001
publication
Arrested B lymphopoiesis and persistence of activated B cells in adult interleukin 7(-/)- mice
Read more01 Sep 2001
publication
Intraembryonic, but not yolk sac hematopoietic precursors, isolated before circulation, provide long-term multilineage reconstitution
Read more15 Jun 2001
publication
Inhibition of Plasmodium yoelii blood-stage malaria by interferon alpha through the inhibition of the production of its target cell, the reticulocyte
Read more01 Jun 2001
01 May 2001
publication
Mice triallelic for the Ig heavy chain locus: implications for VHDJH recombination
Read more01 Apr 2001
01 Mar 2001
publication
CD25+ CD4+ T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10
Read more25 Jan 2001
01 Oct 2000
publication
Disruption of the Rev3l-encoded catalytic subunit of polymerase zeta in mice results in early embryonic lethality
Read more01 Sep 2000
publication
Evidence for two subgroups of CD4-CD8- NKT cells with distinct TCR alpha beta repertoires and differential distribution in lymphoid tissues
Read more01 Aug 2000
publication
Characterization of T cell precursor activity in the murine fetal thymus: evidence for an input of T cell precursors between days 12 and 14 of gestation
Read more01 Apr 2000
publication
Regulatory CD4 T cells control the size of the peripheral activated/memory CD4 T cell compartment
Read more25 Feb 2000
publication
The splanchnopleura/AGM region is the prime site for the generation of multipotent hemopoietic precursors, in the mouse embryo
Read more01 Feb 2000
publication
A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE
Read more25 Jan 2000
publication
Cell fate determination in the hematopoietic system: from the hematopoietic stem cell to the lineage committed progenitors
Read more15 Jan 2000
publication
Frequency and characterization of phenotypic Ig heavy chain allelically included IgM-expressing B cells in mice
Read more01 Jul 1999
publication
Stem cell emergence and hemopoietic activity are incompatible in mouse intraembryonic sites
Read more15 Dec 1998
publication
Ontogeny and phylogeny of commitment and differentiation in the hematopoietic and immune system
Read more15 Oct 1998
01 May 1998
publication
Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis
Read more01 May 1998
publication
Extensive junctional diversity of Ig heavy chain rearrangements generated in the progeny of single fetal multipotent hematopoietic cells in the absence of selection
Read more01 May 1998
01 Apr 1998
publication
Ontogeny of the heavy chain immunoglobulin repertoire in fetal liver and bone marrow
Read more15 Dec 1997
publication
Cellules souches hématopoïétiques intraembryonnaires chez la souris: encore plus tôt
Read more01 Nov 1997
01 Jul 1997
publication
Maternal immunoglobulins have no effect on the rate of maturation of the B cell compartment of the offspring
Read more01 May 1997
01 May 1997
15 Dec 1996
15 Dec 1996
20 Sep 1996
publication
Lymphoid potential, probed before circulation in mouse, is restricted to caudal intraembryonic splanchnopleura
Read more25 Apr 1996
publication
Defects in cardiac outflow tract formation and pro-B-lymphocyte expansion in mice lacking Sox-4
Read more01 Apr 1996
publication
The expansion and selection of T cell receptor alpha beta intestinal intraepithelial T cell clones
Read more01 Jan 1996
15 Dec 1995
15 Dec 1995
15 Dec 1995
15 Dec 1995
15 Dec 1995
15 Dec 1995
15 Dec 1995
18 Aug 1995
15 Dec 1994
publication
Development of B lymphocytes from lymphoid committed and uncommitted progenitors
Read more15 Dec 1994
publication
Developmental events from hemopoietic stem cells to B-cell populations and Ig repertoires
Read more01 Oct 1994
publication
Oligoclonal repertoire of the CD8 alpha alpha and the CD8 alpha beta TCR-alpha/beta murine intestinal intraepithelial T lymphocytes: evidence for the random emergence of T cells
Read more01 Mar 1994
publication
Stromal cell independent growth of bipotent B cell–macrophage precursors from murine fetal liver
Read more15 Dec 1993
15 Jul 1993
publication
Differentiation and characterization of B-cell precursors detected in the yolk sac and embryo body of embryos beginning at the 10- to 12-somite stage
Read more01 Feb 1993
15 Dec 1992
15 Dec 1992
16 Apr 1992
01 Apr 1992
publication
The stromal cell line S17 supports the growth of lipopolysaccharide-stimulated CBA/N spleen cell colonies in vitro
Read more01 Feb 1992
publication
Enrichment and characterization of uncommitted B-cell precursors from fetal liver at day 12 of gestation
Read more01 Jan 1992
01 Sep 1991
publication
Expansion of myelopoietic precursors and inhibition of B-cell precursors in mice that express a T-cell receptor gamma (V gamma 1.1J gamma 4C gamma 4) transgene
Read more01 Jan 1991
01 Oct 1990
15 Dec 1988
01 Jul 1988
publication
Antibody engineering for the analysis of affinity maturation of an anti-hapten response
Read more01 Jan 1988
15 Dec 1987
publication
Timing, genetic requirements and functional consequences of somatic hypermutation during B cell development
Read more20 Nov 1987
15 Dec 1986
01 Nov 1986
01 Oct 1986
publication
Clonal recruitment and somatic mutation in the generation of immunological memory to the hapten NP
Read more01 Oct 1985
publication
Low affinity of kappa chain bearing (4-hydroxy-3-nitrophenyl)acetyl (NP)-specific antibodies in the primary antibody repertoire of C57BL/6 mice may explain lambda chain dominance in primary anti-NP responses
Read more01 May 1985
publication
Structure of primary anti-(4-hydroxy-3-nitrophenyl)acetyl (NP) antibodies in normal and idiotypically suppressed C57BL/6 mice
Read more01 Jan 1977
publication