Timeline

Ana Cumano
Head of Structure
30 Jan 2020
event

Department of Immunology seminar: Fernando Camargo, Lineage analysis at the single cell level

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04 Nov 2019
publication

Maintenance of Type 2 Response by CXCR6-Deficient ILC2 in Papain-Induced Lung Inflammation

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19 Sep 2019
publication

The influence of space and time on the establishment of B cell identity

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27 Jun 2019
publication

Mouse HSA+ immature cardiomyocytes persist in the adult heart and expand after ischemic injury

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26 Apr 2019
publication

New Molecular Insights into Immune Cell Development

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14 Feb 2019
team

Pathophysiology of the immune system, Inserm U1223

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08 Feb 2019
publication

HSA+ immature cardiomyocites persist in the adult heart and expand after ischemic injury

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08 Jan 2019
publication

Mapping structure and biological functions within mesenchymal bodies using microfluidics

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21 Sep 2018
publication

Mouse adult hematopoietic stem cells actively synthetize ribosomal RNA

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27 Jun 2018
event

Immunology Department – Revisiting Genetics of Autoimmunity

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07 Jun 2018
publication

The Notch Signaling Pathway Is Balancing Type 1 Innate Lymphoid Cell Immune Functions

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04 Jun 2018
event

Cell circuit control of lymphocyte development

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10 Apr 2018
publication

Mice with reduced expression of the telomere-associated protein Ft1 develop p53-sensitive progeroid traits

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01 Mar 2018
publication

The Dynamics of Interleukin-10-Afforded Protection during Dextran Sulfate Sodium-Induced Colitis

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26 Feb 2018
event

“cross talk of cells of two distinct hematopoietic lineages”

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12 Jan 2018
publication

PAXX and Xlf interplay revealed by impaired CNS development and immunodeficiency of double KO mice

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17 Oct 2017
publication

Molecular and Functional Characterization of Lymphoid Progenitor Subsets Reveals a Bipartite Architecture of Human Lymphopoiesis

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01 Oct 2017
publication

Guidelines for the use of flow cytometry and cell sorting in immunological studies

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21 Aug 2017
publication

Asynchronous lineage priming determines commitment to T cell and B cell lineages in fetal liver

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05 May 2017
publication

Analysis of Cell Suspensions Isolated from Solid Tissues by Spectral Flow Cytometry

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13 Apr 2017
event

“Lymphocyte development and lineage commitment in the embryo” by Ana Cumano

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31 Jan 2017
project

The role of lncRNA H19 in Thymopoiesis

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19 Jan 2017
publication

Single-cell gene expression using multiplex RT-qPCR to characterize heterogeneity of rare lymphoid populations

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13 Jan 2017
event

Max D Cooper seminar

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13 Jan 2017
event

Guillaume Desanti seminar

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08 Aug 2016
publication

Spectral Cytometry Has Unique Properties Allowing Multicolor Analysis of Cell Suspensions Isolated from Solid Tissues

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20 May 2016
publication

Fetal B cell development

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03 May 2016
publication

Notch signaling in group 3 innate lymphoid cells modulates their plasticity

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29 Apr 2016
publication

The cyclin D1 carboxyl regulatory domain controls the division and differentiation of hematopoietic cells

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21 Mar 2016
publication

Estrogen-mediated downregulation of AIRE influences sexual dimorphism in autoimmune diseases

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18 Jan 2016
publication

Single-Cell Gene Expression Analyses Reveal Heterogeneous Responsiveness of Fetal Innate Lymphoid Progenitors to Notch Signaling

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01 Oct 2015
publication

CXCR6 Expression Is Important for Retention and Circulation of ILC Precursors

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01 Jul 2015
project

T cell development

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09 Jun 2015
publication

Characterization of Thymic Settling Progenitors in the Mouse Embryo Using In Vivo and In Vitro Assays

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01 Jun 2015
publication

Osteoblast-specific expression of the fibrous dysplasia (FD)-causing mutation Gsα(R201C) produces a high bone mass phenotype but does not reproduce FD in the mouse

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11 May 2015
team

Lymphopoiesis

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01 Nov 2014
publication

Constitutive expression of Gsα(R201C) in mice produces a heritable, direct replica of human fibrous dysplasia bone pathology and demonstrates its natural history

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14 Jul 2014
publication

Sca-1+ cardiac progenitor cells and heart-making: a critical synopsis

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25 Jan 2014
publication

Hematopoiesis during embryonic development

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08 Dec 2013
publication

Two waves of distinct hematopoietic progenitor cells colonize the fetal thymus

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23 Sep 2013
publication

Notchless-dependent ribosome synthesis is required for the maintenance of adult hematopoietic stem cells

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13 Sep 2013
publication

Embryonic hematopoiesis

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05 Aug 2013
publication

Origin, trafficking, and intraepithelial fate of gut-tropic T cells

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01 Apr 2013
publication

A novel murine model of rhinoscleroma identifies Mikulicz cells, the disease signature, as IL-10 dependent derivatives of inflammatory monocytes

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03 Jan 2013
publication

GATA-3 promotes T-cell specification by repressing B-cell potential in pro-T cells in mice

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12 Sep 2012
publication

Inhibitors of DNA binding proteins restrict T cell potential by repressing Notch1 expression in Flt3-negative common lymphoid progenitors

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16 Aug 2012
publication

Immature hematopoietic stem cells undergo maturation in the fetal liver

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24 Feb 2012
publication

Myf5 haploinsufficiency reveals distinct cell fate potentials for adult skeletal muscle stem cells

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11 Jan 2012
publication

Temporal predisposition to αβ and γδ T cell fates in the thymus

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08 Dec 2011
publication

Characterization of Pax3-expressing cells from adult blood vessels

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11 Sep 2011
publication

Notch signaling is necessary for adult, but not fetal, development of RORγt(+) innate lymphoid cells

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01 Jul 2011
publication

Msx genes define a population of mural cell precursors required for head blood vessel maturation

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08 Dec 2010
publication

Transcriptome analyses based on genetic screens for Pax3 myogenic targets in the mouse embryo

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14 Oct 2010
publication

Sumoylation by Ubc9 regulates the stem cell compartment and structure and function of the intestinal epithelium in mice

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16 Apr 2010
publication

CpG inhibits pro-B cell expansion through a cathepsin B-dependent mechanism

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13 Mar 2010
publication

Reduced EBF expression underlies loss of B-cell potential of hematopoietic progenitors with age

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01 Dec 2009
publication

Pax3:Foxc2 reciprocal repression in the somite modulates muscular versus vascular cell fate choice in multipotent progenitors

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01 Nov 2009
publication

Numb promotes an increase in skeletal muscle progenitor cells in the embryonic somite

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28 Oct 2009
publication

An adult tissue-specific stem cell in its niche: a gene profiling analysis of in vivo quiescent and activated muscle satellite cells

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28 Jul 2009
publication

Muscle stem cell behavior is modified by microRNA-27 regulation of Pax3 expression

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19 May 2009
publication

Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim sustains B lymphopoiesis in the absence of IL-7

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01 May 2009
publication

Inflammation recapitulates the ontogeny of lymphoid stromal cells

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09 Mar 2009
publication

CX3CR1+ CD115+ CD135+ common macrophage/DC precursors and the role of CX3CR1 in their response to inflammation

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21 Jan 2009
publication

Characterization of the thymic IL-7 niche in vivo

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12 Nov 2008
publication

Neurotoxic activation of microglia is promoted by a nox1-dependent NADPH oxidase

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10 Apr 2008
publication

Separation of splenic red and white pulp occurs before birth in a LTalphabeta-independent manner

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01 Mar 2008
publication

Are hematopoietic stem cells generated in the placenta?

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01 Mar 2008
publication

Early neuronal and glial fate restriction of embryonic neural stem cells

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12 Feb 2008
publication

Identification of CD4int progenitors in mouse fetal spleen, a source of resident lymphoid cells

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01 Aug 2007
publication

Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior

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01 Mar 2007
publication

Reply to ‘Alice Dautry’ profile

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01 Jan 2007
publication

Ontogeny of the hematopoietic system

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01 Oct 2006
publication

A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127

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16 Aug 2006
publication

Fetal spleen stroma drives macrophage commitment

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08 Jun 2006
publication

Ontogeny, function, and peripheral homeostasis of regulatory T cells in the absence of interleukin-7

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01 May 2006
publication

Processing of the bovine spongiform encephalopathy-specific prion protein by dendritic cells

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25 Jan 2006
publication

Hematopoietic stem cell development

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27 Dec 2005
publication

Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells

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01 Dec 2005
publication

A clonogenic bone marrow progenitor specific for macrophages and dendritic cells

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01 Sep 2005
publication

Direct isolation of satellite cells for skeletal muscle regeneration

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01 Aug 2005
publication

Numbers of Foxp3-expressing CD4+CD25high T cells do not correlate with the establishment of long-term tolerance after allogeneic stem cell transplantation

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14 Jul 2005
publication

Three pathways to mature macrophages in the early mouse yolk sac

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14 Mar 2005
publication

Interleukin-7 is necessary to maintain the B cell potential in common lymphoid progenitors

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01 Mar 2005
publication

In vivo and in absence of a thymus, the enforced expression of the Notch ligands delta-1 or delta-4 promotes T cell development with specific unique effects

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01 Jan 2005
publication

Of birds and mice: hematopoietic stem cell development

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01 Jan 2005
publication

Hematopoietic stem cell development during mouse embryogenesis

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27 Dec 2004
publication

Characterization of purified intraembryonic hematopoietic stem cells as a tool to define their site of origin

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14 Oct 2004
publication

The notch ligand Delta1 recruits Dlg1 at cell-cell contacts and regulates cell migration

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27 Sep 2004
publication

Regulatory potential and control of Foxp3 expression in newborn CD4+ T cells

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19 Jul 2004
publication

Pre-B cell receptor expression is necessary for thymic stromal lymphopoietin responsiveness in the bone marrow but not in the liver environment

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25 Jan 2004
publication

Hematopoietic stem cell development during mouse embryogenesis

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01 Jan 2004
publication

Differentiation of B lymphocytes from hematopoietic stem cells

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09 Dec 2003
publication

IkappaBalpha/IkappaBepsilon deficiency reveals that a critical NF-kappaB dosage is required for lymphocyte survival

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19 Nov 2003
publication

Primordial hematopoietic stem cells generate microglia but not myelin-forming cells in a neural environment

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20 Jul 2003
publication

Thymic stromal-derived lymphopoietin distinguishes fetal from adult B cell development

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31 Mar 2003
publication

Monoallelic expression of the murine gene encoding Toll-like receptor 4

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01 Feb 2003
publication

The repertoires of circulating human CD8(+) central and effector memory T cell subsets are largely distinct

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01 Dec 2002
publication

Lymphocyte commitment during embryonic development, in the mouse

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01 Aug 2002
publication

The hare and the tortoise: an embryonic haematopoietic race

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15 Jan 2002
publication

Identification of the earliest prethymic bipotent T/NK progenitor in murine fetal liver

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01 Jan 2002
publication

Deoxyguanosine blocks allograft rejection of thymic epithelium but not lymphocyte infiltration and recognition

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01 Nov 2001
publication

Embryonic thymic epithelium naturally devoid of APCs is acutely rejected in the absence of indirect recognition

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15 Oct 2001
publication

Arrested B lymphopoiesis and persistence of activated B cells in adult interleukin 7(-/)- mice

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01 Sep 2001
publication

Intraembryonic, but not yolk sac hematopoietic precursors, isolated before circulation, provide long-term multilineage reconstitution

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15 Jun 2001
publication

Inhibition of Plasmodium yoelii blood-stage malaria by interferon alpha through the inhibition of the production of its target cell, the reticulocyte

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01 Jun 2001
publication

Identification of committed NK cell progenitors in adult murine bone marrow

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01 May 2001
publication

Mice triallelic for the Ig heavy chain locus: implications for VHDJH recombination

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01 Apr 2001
publication

Pluripotent hematopoietic stem cell development during embryogenesis

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01 Mar 2001
publication

CD25+ CD4+ T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10

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25 Jan 2001
publication

Changes in lymphoid progenitor populations during mammalian development

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01 Oct 2000
publication

Disruption of the Rev3l-encoded catalytic subunit of polymerase zeta in mice results in early embryonic lethality

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01 Sep 2000
publication

Evidence for two subgroups of CD4-CD8- NKT cells with distinct TCR alpha beta repertoires and differential distribution in lymphoid tissues

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01 Aug 2000
publication

Characterization of T cell precursor activity in the murine fetal thymus: evidence for an input of T cell precursors between days 12 and 14 of gestation

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01 Apr 2000
publication

Regulatory CD4 T cells control the size of the peripheral activated/memory CD4 T cell compartment

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25 Feb 2000
publication

The splanchnopleura/AGM region is the prime site for the generation of multipotent hemopoietic precursors, in the mouse embryo

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01 Feb 2000
publication

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

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25 Jan 2000
publication

Cell fate determination in the hematopoietic system: from the hematopoietic stem cell to the lineage committed progenitors

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15 Jan 2000
publication

Frequency and characterization of phenotypic Ig heavy chain allelically included IgM-expressing B cells in mice

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01 Jul 1999
publication

Stem cell emergence and hemopoietic activity are incompatible in mouse intraembryonic sites

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15 Dec 1998
publication

Ontogeny and phylogeny of commitment and differentiation in the hematopoietic and immune system

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15 Oct 1998
publication

Critical involvement of Tcf-1 in expansion of thymocytes

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01 May 1998
publication

Development of T cell precursor activity in the murine fetal liver

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01 May 1998
publication

Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis

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01 May 1998
publication

Extensive junctional diversity of Ig heavy chain rearrangements generated in the progeny of single fetal multipotent hematopoietic cells in the absence of selection

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01 Apr 1998
publication

Ontogeny of the heavy chain immunoglobulin repertoire in fetal liver and bone marrow

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15 Dec 1997
publication

Cellules souches hématopoïétiques intraembryonnaires chez la souris: encore plus tôt

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01 Nov 1997
publication

TCR-beta repertoire development in the mouse embryo

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01 Jul 1997
publication

Maternal immunoglobulins have no effect on the rate of maturation of the B cell compartment of the offspring

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01 May 1997
publication

Sox-4 facilitates thymocyte differentiation

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01 May 1997
publication

Does positive selection determine the B cell repertoire?

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15 Dec 1996
publication

Hematopoietic growth factors involved in B cell development

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15 Dec 1996
publication

Detection of multipotent hematopoietic cells, in pre-liver embryos

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20 Sep 1996
publication

Lymphoid potential, probed before circulation in mouse, is restricted to caudal intraembryonic splanchnopleura

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25 Apr 1996
publication

Defects in cardiac outflow tract formation and pro-B-lymphocyte expansion in mice lacking Sox-4

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01 Apr 1996
publication

The expansion and selection of T cell receptor alpha beta intestinal intraepithelial T cell clones

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01 Jan 1996
publication

Circulation of hematopoietic progenitors in the mouse embryo

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15 Dec 1995
publication

B-lymphoid potential in pre-liver mouse embryo

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15 Dec 1995
publication

Introduction: In-vitro models of lymphocyte differentiation

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15 Dec 1995
publication

Hematopoietic cell commitment during embryonic development

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15 Dec 1995
publication

Sites of hemopoietic stem cell production in early embryogenesi

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15 Dec 1995
publication

Hématopoïèse intraembryonnaire chez la souris

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15 Dec 1995
publication

The TcRb chain repertoire of gut-derived T lymphocyteb

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15 Dec 1995
publication

Intra-embryonic hemopoiesis in mice

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18 Aug 1995
publication

PCR-based analysis of the murine immunoglobulin heavy-chain repertoire

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15 Dec 1994
publication

Development of B lymphocytes from lymphoid committed and uncommitted progenitors

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15 Dec 1994
publication

Developmental events from hemopoietic stem cells to B-cell populations and Ig repertoires

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01 Oct 1994
publication

Oligoclonal repertoire of the CD8 alpha alpha and the CD8 alpha beta TCR-alpha/beta murine intestinal intraepithelial T lymphocytes: evidence for the random emergence of T cells

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01 Mar 1994
publication

Stromal cell independent growth of bipotent B cell–macrophage precursors from murine fetal liver

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15 Dec 1993
publication

Developmental relationships between hemopoiesis and vasculogenesis

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15 Jul 1993
publication

Differentiation and characterization of B-cell precursors detected in the yolk sac and embryo body of embryos beginning at the 10- to 12-somite stage

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01 Feb 1993
publication

B cell developmental defects in X-linked immunodeficiency

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15 Dec 1992
publication

The kappa:lambda ratio and B cell development in fetal liver

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15 Dec 1992
publication

B cell commitment

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16 Apr 1992
publication

Bipotential precursors of B cells and macrophages in murine fetal liver

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01 Apr 1992
publication

The stromal cell line S17 supports the growth of lipopolysaccharide-stimulated CBA/N spleen cell colonies in vitro

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01 Feb 1992
publication

Enrichment and characterization of uncommitted B-cell precursors from fetal liver at day 12 of gestation

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01 Jan 1992
publication

Growth and differentiation of a bipotent precursor of B cells and macrophages

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01 Sep 1991
publication

Expansion of myelopoietic precursors and inhibition of B-cell precursors in mice that express a T-cell receptor gamma (V gamma 1.1J gamma 4C gamma 4) transgene

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01 Jan 1991
publication

Factors produced by stromal cells involved in B-cell development

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01 Oct 1990
publication

The influence of S17 stromal cells and interleukin 7 on B cell development

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15 Dec 1988
publication

Effects of surgical stress on lymphoid populations of mice

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01 Jul 1988
publication

Antibody engineering for the analysis of affinity maturation of an anti-hapten response

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01 Jan 1988
publication

Modulation of antibody binding affinity by somatic mutation

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15 Dec 1987
publication

Timing, genetic requirements and functional consequences of somatic hypermutation during B cell development

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20 Nov 1987
publication

Evolutionary and somatic selection of the antibody repertoire in the mouse

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15 Dec 1986
publication

Mutation and selection of antibodies

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01 Nov 1986
publication

Effects of hydroxyurea in vivo treatment on the antibody response in mice

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01 Oct 1986
publication

Clonal recruitment and somatic mutation in the generation of immunological memory to the hapten NP

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01 Oct 1985
publication

Low affinity of kappa chain bearing (4-hydroxy-3-nitrophenyl)acetyl (NP)-specific antibodies in the primary antibody repertoire of C57BL/6 mice may explain lambda chain dominance in primary anti-NP responses

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01 May 1985
publication

Structure of primary anti-(4-hydroxy-3-nitrophenyl)acetyl (NP) antibodies in normal and idiotypically suppressed C57BL/6 mice

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01 Jan 1977
publication

Instantaneous assessments of left ventricular dimensions by ultrasonic analogue conversion system. I. An experimental study

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