Inserm Unit 1223 (Pathophysiology of the Immune System) comprises four laboratories within the Immunology Department of the Institut Pasteur: Innate Immunity Unit (James Di Santo), Lymphopoiesis Unit (Ana Cumano), Dynamics of Immune Response Unit (Philippe Bousso) and Immunobiology of Dendritic Cells Unit (Stanislas Pol). Together, we pursue collaborative projects aiming to better understand lymphocyte development, differentiation and functional dynamics under normal steady-state conditions and during inflammation or infection in mouse and man.
James Di Santo
Dynamics of Immune Responses
Immunobiology of Dendritic Cells
2019Exhaustion and senescence marker profiles on human T cells in BRGSF-A2 humanized mice resemble those in human samples, J. Leukoc. Biol. 2019 Aug;.
2019An Id2-Reporter Mouse Redefines Innate Lymphoid Cell Precursor Potentials, Immunity 2019 Apr;50(4):1054-1068.e3.
2019Accelerated thymopoiesis and improved T cell responses in HLA-A2/-DR2 transgenic BRGS-based human immune system mice, Eur. J. Immunol. 2019 Mar;.
2019Modeling Infectious Diseases in Mice with a “Humanized” Immune System, Microbiol Spectr 2019 03;7(2).
2019Editorial overview: Pillars of innate immunity: constantly learning and trying to remember, Curr. Opin. Immunol. 2019 Feb;56:iii-vi.
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