The Quantitative Biology program of the Institut Pasteur is intended to facilitate research and education at the interface of biology and the more quantitative sciences. One of the major aims of Quantitative Biology is thus to understand the underlying principles of complex biological behavior in terms of physical and mathematical models. This approach overarches all fields of biology.
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Coordination
Teams
Laboratory
UMR
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Pathogenesis of vascular infections
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Guillaume Dumenil
Laboratory
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Dynamics of Host-Pathogen Interactions
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Jost Enninga
Laboratory
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Imaging and Modeling
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Christophe Zimmer
Laboratory
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Dynamics of Developmental Decisions in Drosophila
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François Schweisguth
Laboratory
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Cell Polarity, Migration And Cancer
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Sandrine Etienne-Manneville
Laboratory
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Human Evolutionary Genetics
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Lluis Quintana-Murci
Laboratory
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Structural Bioinformatics
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Michael Nilges
Laboratory
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Biological Image Analysis
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Jean-Christophe Olivo-Marin
Laboratory
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Heart Morphogenesis
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Sigolène Meilhac
Group
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Neural circuits for spatial navigation and memory
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Christoph Schmidt-Hieber
Laboratory
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Membrane Traffic and Pathogenesis
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Chiara Zurzolo
Group
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Group: Translation dependent mRNA degradation
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Cosmin Saveanu
Laboratory
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Spatial Regulation of Genomes
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Romain Koszul
Laboratory
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Zebrafish Neurogenetics
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Laure Bally-Cuif
Laboratory
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Auditory Therapies Innovation Lab
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Christine Petit
Laboratory
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Biochemistry of Macromolecular Interactions
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Daniel Ladant
Platform
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Molecular Biophysics
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Patrick England
Laboratory
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Stem Cells And Development
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Shahragim Tajbakhsh
Laboratory
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Bacterial Genome Plasticity
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Didier Mazel
Laboratory
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Synthetic Biology
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David Bikard
Group
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BiophysiCyaA
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Alexandre Chenal
Laboratory
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Dynamic Regulation of Morphogenesis
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Jérôme Gros
Laboratory
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InBio: Experimental and Computational Methods for Modeling Cellular Processes
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Grégory Batt
Group
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Synapse and Circuit Dynamics
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David DiGregorio
Laboratory
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Neural Circuit Dynamics and Decision Making
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Florent Haiss
Laboratory
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Physical Microfluidics and Bioengineering
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Charles Baroud
Laboratory
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Cell death and epithelial homeostasis
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Romain Levayer
Laboratory
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Physics of Biological Function
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Thomas Gregor
Laboratory
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Decision and Bayesian Computation
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Jean-Baptiste Masson
Jobs
Qbio Symposia
• October 17th 2016: “Kick off meeting” of the Qbio program (Guillaume Duménil, Sven van Teeffelen)
• June 9th 2017: “Forces in Biology” (Romain Levayer, Nicolas Dray, Sandrine Etienne-Manneville, Patrick England, Alexandre Dufour).
• May 25th 2018: “Physics of Biological Membranes” (Thomas Wollert (IP), Patricia Bassereau (Curie))
• October 11-12 2018: “Neural networks – from machines to brains” (David Di Gregorio, JB Masson, and Christoph Schmidt-Hieber (IP), Rémi Monasson (ENS))
• January 2019: “Quantitative cell biology of bacteria“ (Guillaume Duménil, Sven van Teeffelen)
• June 2021: “Bridging the scales, from single cells, to populations, tissues and organs” (Charles Baroud, Romain Levayer)
• October 2021: “The physics of cancer” (Sandrine Etienne-Manneville, Romain Levayer, jointly with the Cancer intiative)
• December 2022: “MeMoDEvo: Mechanics, Morphogenesis, Development and Evolution” (Thibaut Brunet, Romain Levayer, Katja Heuer and Roberto Toro)
Contacts
If you wish to be informed by email please sign up on the Qbio@pasteur.fr mailing list. Connect to this address : https://email.pasteur.fr/ Go to the Settings menu then options and then groups and sign-in.
Quantitative biology at the Institut Pasteur
Many Pasteur laboratories are integrating physical approaches in their studies ranging from structural biology, via cell biology, to infection, neurobiology and development.
• Multiscale self-organization is studied at the level of protein machineries in bacteria, cytoskeleton during the migration of eucaryotic cells and organizaton of tissues during development.
• Cellular and tissue mechanics are explored during bacterial aggregation, grastrulation and heart development as well as during amoebae movement.
• Information processing and signaling are studied in the context of neurobiology, 3D genome architecture, transciption and cell decision making.
Objectives of the Qbio program at Institut Pasteur
The Quantitative Biology program aims to encourage these developments on campus. The major purpose of this program is:
• To foster interactions between scientists involved in Quantitative Biology at Institut Pasteur through seminars and mini-symposiums.
• To bring quantitatively trained scientists into biology
• To encourage biologists to integrate quantitative models into their research
Qbio progress reports:
The Qbio programm organise monthly progress reports where early career scientists (PhD, postdoc) present ongoing projects at the interface between biology, physics and/or mathematics in an informal setting. The primary aim is to foster interactions on the campus. The meetings currently take place online and on site on Thursdays at 2pm every month. Contact the organisers if you would like to join.