The Unit for the Physics of Biological Function studies the basic physical principles that govern the existence of multicellular life. A core focus of the lab is to understand biological development–the complex process through which an organism grows from a single cell into a differentiated, multicellular organism–from a physics perspective. As such, we formulate and experimentally validate quantitative models that describe how individual cells interact and organize in order to generate complex life forms.
Our main interests lie in:
- multicellular pattern formation
- transcriptional regulation in the context of development
- molecular limits to biochemical sensing
- emergence of collective behaviors in multicellular systems.
Our main tools consist in:
- live and super-resolution microscopy
- genome editing and genetics
- image analysis and quantitative modeling
- instrument design and development.
Work with us
We are seeking postdoc candidates with interests in the broader fields of biophysics and/or cell and developmental biology. In particular, with expertise in one or some of the following specific areas: nonlinear and ultrafast optics, super-resolution imaging, instrumentation (design and implementation), photomanipulation, optogenetics, advanced image analysis, live imaging of stem cells, tissues, or embryos.
Specific topics (in progress…):
- lattice light-sheet super-resolution imaging
- optogenetic pathway activation