The Synthetic Biology Group is interested in applying genetic engineering technologies to better understand pathogenic bacteria and fight them.
The rise of emerging pathogens and antibiotic resistances is becoming a major public health issue. Using engineering principles we are creating new strategies to quickly decipher the mechanisms of bacterial virulence and provide tools to specifically kill antibiotic resistant and virulent bacteria. In particular we are studying the bacterial immune system known as CRISPR, and developing novel CRISPR tools to edit bacterial genomes, control their gene expression and specifically eliminate dangerous bacteria.
Engineering bacteria with CRISPR (iBiology talk)