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About

“Nature is the best doctor: she cures three out of four illnesses, and she never speaks ill on her colleagues.”
Louis Pasteur

Our research is focused on understanding how natural selection, human demography and lifestyle have shaped the patterns of diversity of the human genome, to understand how this may impact phenotype variation and disease. Our current projects aim to to increase our understanding of (i) the genetic architecture of human populations, migrations patterns and admixture events; (ii) the occurrence of positive selection in the human genome and the relationship between population demography and the burden of deleterious alleles; (iii) the genetic and epigenetic determinants of immunity-related traits, with an emphasis on molecular phenotypes such as gene and miRNA expression; and (iv) the relationship between genetic diversity, epigenetic patterns (in particular DNA methylation) and changes in lifestyle and habitat of human populations.

To this end, our laboratory combines population genetics and cellular genomic approaches, with computational modelling and development of new statistical frameworks, often working closely to theoretical population geneticists, immunologists, epidemiological geneticists as well as anthropologists.

 

Members

Former Members

2000
2000
Name
Position
2015
2020
Katherine Siddle
2015
2020
Julien Pothlichet
2015
2020
Eddie Loh
2015
2020
Stéphane Pereygne
2015
2020
Choumouss Kamoun
2015
2020
Estelle Vasseur
2015
2020
Jérémy Manry
2015
2020
Simona Fornarino
2015
2020
Meriem Ben Ali
2015
2020
Michele Boniotto
2015
2020
Luis B. Barreiro
2015
2020
Jessica Guibert
2015
2020
Francesca Luca
2015
2020
Paul Verdu
2015
2020
Eric Kramer
2015
2020
Maud Fagny
PhD Student
2015
2020
Matthieu Deschamps
PhD Student
2015
2020
Barbara Piasecka
Research Engineer
2015
2020
Romuald Laso-Jadart
Undergraduate Student
2015
2020
João C. Teixeira
Post-doc
2015
2020
Athanasios Kousathanas
Post-doc
2015
2020
Sadoune AIT KACI AZZOU
Post-doc
2015
2020
Nora Zidane
Research Engineer
2015
2020
Cécile Roux
Administrative Staff
2015
2020
Hélène Quach
Project Manager
2015
2020
Marie Lopez
Post-doc
2015
2020
Lucas Husquin
PhD Student
2015
2020
Martin SILVERT
PhD Student

Projects

Transversal Project

Fundings

Publications

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Contact

Unit Human Evolutionary Genetics 25-28 Rue du Docteur Roux 75015, Paris France Phone: 33 1 40 61 34 43 Fax: 33 1 45 68 87 27 Email: quintana@pasteur.fr