Heart Morphogenesis

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member
team
department
center
program_project
nrc
whocc
project
software
tool
patent

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Administrative Staff
Clinical Research Assistant
Graduate Student
Lab assistant
Non-permanent Researcher
Permanent Researcher
PhD Student
Physician
Post-doc
Project Manager
Research Engineer
Retired scientist
Technician
Undergraduate Student
Visiting Scientist

Appointments

Deputy Director of Center
Deputy Director of Department
Deputy Director of National Reference Center
Director of Center
Director of Department
Director of Institute
Director of National Reference Center
Group Leader
Head of Facility
Head of Structure
Honorary President of the Departement
Labex Coordinator

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Molecular Mechanisms of Membrane Transport

Pathogenesis of Bacterial Anaerobes

Scientific Fields

Diseases

Organisms

Applications

Technique

Scientific Fields

Diseases

Organisms & Organs

Model systems
Mouse

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About

The Imagine-Institut Pasteur group of Heart Morphogenesis studies how cells are coordinated at the level of the tissue and how their local behaviour generates global changes of organ shape.

We address these questions in the context of heart development, using approaches of genetics, cell biology, 3D imaging and computer modelling. Our work in the mouse is relevant to congenital heart defects and heart repair in humans.

Members

Sigolène Meilhac

Head of Structure

Head

Jean-François Le Garrec

Marie Demeslay-Gougam

Administrative Staff

Morphogenesis, that is the acquisition of a shape, is essential for organ function. It has been well characterised at a molecular level, with the identification of signalling pathways regulating gene expression. A current question […]

project

Ongoing

7 Members

Mechanism of heart growth

Sigolène Meilhac (PI)

Growth of the heart is required to adapt to the increasing hemodynamic load of the developing organism. Physiologically, heart growth is mainly driven by the proliferation of myocardial cells in utero and by cell […]

Transversal Project

Inception – Institut Convergence for the study of Emergence of Pathology Through Individuals and Populations

Inception Goal The Inception’s goal is to develop a core structure to mobilize data resources, numerical sciences, and fundamental experimental biology in a range of health issues. Inception program uses Integrative Biology, Social Science […]

Quantitative biology

The Quantitative Biology program of the Institut Pasteur is intended to facilitate research and education at the interface of biology and the more quantitative sciences. One of the major aims of Quantitative Biology is thus to […]