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© Romain Levayer, Institut Pasteur
Epithelial layer of the Drosophila pupal thorax (notum). White : cell contour (E-cadherin), pseudocolour : Dpp sensor.

Transversal Projects

The IP Stem Cell Initiative

The Stem Cell Concept – Constructing, Deconstructing and Reconstructing Tissues for organismal health Human biology and molecular medicine are rapidly becoming data-rich fields that are fueled in part by large-scale longitudinal studies of patients […]

Quantitative biology

The Quantitative Biology program of the Institut Pasteur is intended to facilitate research and education at the interface of biology and the more quantitative sciences. One of the major aims of Quantitative Biology is thus to […]

LabEx Revive – Regenerative biology & medicine

Rationale and Objectives of Revive Consortium Major advancements in stem cell biology have paved the way for concerted research activities on the fundamental biology of stem cells and their applications in the clinic. The […]

Projects

Project
Ongoing
2 Members

ERC Consolidator Grant PrApEDoC: Predicting Apoptosis Engagement Downstream of Caspasese

Romain Levayer (PI)

Epithelial cell death is widespread during development and tissue homeostasis. While the core pathway of apoptosis is well known, we lack predictive power to understand when and where a specific cell will die in […]
Project
Ongoing
4 Members

Commitment to apoptosis and the orchestration of cell clearance

Romain Levayer (PI)

Despite the detailed characterisation of the molecular players of apoptosis, its orchestration and fine regulation in multicellular contexts is not well understood. While apoptosis is often considered as a simple binary process, there are nowadays many evidences showing […]
Project
Ongoing
8 Members

ERC-2017-StG_CoSpaDD: Competition for space in development and disease

Romain Levayer (PI)

Despite our deep knowledge of the pathways regulating cell proliferation, growth and survival, we still do not understand how single cells can match their behavior to properties of the entire tissue (including its size and shape).  Mechanical […]

CV

I did my bachelor studies in the Ecole Normale Supérieure in Paris. After a long hesitation between evolution, ecology and developmental and cell biology, a long internship working on C. elegans early development (in Pr. Seydoux lab, John Hopkins University) definitly pushed me toward cell and developmental biology side. My interest for quantitative approaches brought me to an interdisciplinary master (AIV, Paris) where I start being interested by morphogenesis. I then joinded the laboratory of Thomas Lecuit (IBDM, Marseille, France) to start my PhD working on epithelial morphogenesis in early Drosophila embryo and the role of the modulation of cell-cell adhesion. I then moved to Switzerland in the group of Eduardo Moreno for my postdoc (IZB, University of Bern) working on cell competition. I eventually moved back to Paris in December 2016 to start my research group in the Institut Pasteur.  .

Publications

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