Timeline
Olivier Schwartz
Head of Structure
13 Mar 2024
publication
Distinct evolution of SARS-CoV-2 Omicron XBB and BA.2.86/JN.1 lineages combining increased fitness and antibody evasion.
Read more13 Dec 2023
25 Oct 2023
09 Aug 2023
14 Jun 2023
publication
Complement-dependent mpox-virus-neutralizing antibodies in infected and vaccinated individuals.
Read more01 Jun 2023
publication
Estimated protection against COVID-19 based on predicted neutralisation titres from multiple antibody measurements in a longitudinal cohort, France, April 2020 to November 2021.
Read more17 May 2023
28 Feb 2023
publication
Exposure to Secreted Bacterial Factors Promotes HIV-1 Replication in CD4+ T Cells.
Read more14 Feb 2023
publication
Resistance of Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 to neutralizing antibodies.
Read more25 Nov 2022
publication
Defective activation and regulation of type I interferon immunity is associated with increasing COVID-19 severity.
Read more17 Nov 2022
publication
Longitudinal analysis of serum neutralization of SARS-CoV-2 Omicron BA.2, BA.4, and BA.5 in patients receiving monoclonal antibodies.
Read more05 Oct 2022
publication
Duration of BA.5 neutralization in sera and nasal swabs from SARS-CoV-2 vaccinated individuals, with or without omicron breakthrough infection.
Read more01 Sep 2022
publication
Neutralising antibody responses to SARS-CoV-2 omicron among elderly nursing home residents following a booster dose of BNT162b2 vaccine: A community-based, prospective, longitudinal cohort study.
Read more27 Aug 2022
22 Jul 2022
publication
Tracking receptor motions at the plasma membrane reveals distinct effects of ligands on CCR5 dynamics depending on its dimerization status.
Read more15 Jul 2022
publication
Y RNAs are conserved endogenous RIG-I ligands across RNA virus infection and are targeted by HIV-1
Read more15 Jul 2022
publication
C910 chemical compound inhibits the traffiking of several bacterial AB toxins with cross-protection against influenza virus.
Read more08 Jul 2022
publication
Kinetics of the SARS-CoV-2 Antibody Avidity Response Following Infection and Vaccination.
Read more04 Jul 2022
publication
Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2.
Read more17 Jun 2022
news
New publication – Potent Human Broadly SARS-CoV-2 Neutralizing IgA and IgG Antibodies Effective Against Omicron BA.1 and BA.2
Read more01 Jun 2022
publication
Serum neutralization of SARS-CoV-2 Omicron sublineages BA.1 and BA.2 in patients receiving monoclonal antibodies.
Read more04 May 2022
publication
Identification of DAXX as a restriction factor of SARS-CoV-2 through a CRISPR/Cas9 screen.
Read more11 Apr 2022
publication
Transient viral exposure drives functionally-coordinated humoral immune responses in HIV-1 post-treatment controllers.
Read more08 Apr 2022
news
New publication – Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller
Read more12 Mar 2022
publication
Fusogenicity and neutralization sensitivity of the SARS-CoV-2 Delta sublineage AY.4.2.
Read more07 Mar 2022
publication
Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller.
Read more25 Feb 2022
02 Feb 2022
publication
Broadly neutralizing anti-HIV-1 antibodies tether viral particles at the surface of infected cells.
Read more01 Feb 2022
26 Jan 2022
publication
Low CCR5 expression protects HIV-specific CD4+ T cells of elite controllers from viral entry.
Read more01 Jan 2022
publication
Robust and Functional Immune Memory Up to 9 Months After SARS-CoV-2 Infection: A Southeast Asian Longitudinal Cohort.
Read more01 Nov 2021
publication
Release of infectious virus and cytokines in nasopharyngeal swabs from individuals infected with non-alpha or alpha SARS-CoV-2 variants: an observational retrospective study.
Read more17 Sep 2021
publication
Sex Differences in the Evolution of Neutralizing Antibodies to Severe Acute Respiratory Syndrome Coronavirus 2.
Read more01 Sep 2021
publication
Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection.
Read more18 Aug 2021
18 Aug 2021
publication
Bystander CD4 T-cell death is inhibited by broadly neutralizing anti-HIV antibodies only at levels blocking cell-to-cell viral transmission.
Read more14 Aug 2021
publication
A monocyte/dendritic cell molecular signature of SARS-CoV-2 related multisystem inflammatory syndrome in children (MIS-C) with severe myocarditis.
Read more01 Aug 2021
publication
Transmission of SARS-CoV-2 Alpha Variant (B.1.1.7) From a BNT162b2-Vaccinated Individual.
Read more01 Aug 2021
publication
Immune checkpoint inhibitors increase T cell immunity during SARS-CoV-2 infection.
Read more30 Jul 2021
28 Jul 2021
publication
SUMOylation of SAMHD1 at Lysine 595 is required for HIV-1 restriction in non-cycling cells.
Read more22 Jul 2021
news
SARS-CoV-2 : induces the dedifferentiation of multiciliated cells and impairs mucociliary clearance
Read more14 Jul 2021
publication
Analysis of T cell responses directed against the spike and/or membrane and/or nucleocapsid proteins in chilblain-like lesions patients during the COVID-19 pandemic.
Read more08 Jul 2021
02 Jul 2021
publication
Pregnancy complications and Interferon-induced transmembrane proteins (IFITM): balancing antiviral immunity and placental development.
Read more11 Jun 2021
news
COVID-19: sensitivity of the Indian variant (B.1.617.2) to monoclonal antibodies and sera from convalescent and vaccinated individuals
Read more18 May 2021
publication
Asymptomatic and symptomatic SARS-CoV-2 infections elicit polyfunctional antibodies.
Read more01 Apr 2021
publication
SARS-CoV-2 infection in schools in a northern French city: a retrospective serological cohort study in an area of high transmission, France, January to April 2020
Read more08 Feb 2021
publication
Rapid decline of neutralizing antibodies against SARS-CoV-2 among infected healthcare workers.
Read more01 Feb 2021
20 Jan 2021
01 Jan 2021
01 Dec 2020
20 Oct 2020
09 Sep 2020
02 Sep 2020
publication
A comparison of four serological assays for detecting anti–SARS-CoV-2 antibodies in human serum samples from different populations
Read more01 Sep 2020
publication
Serologic responses to SARS-CoV-2 infection among hospital staff with mild disease in eastern France.
Read more01 Jun 2020
publication
Efficacy of Ultrasound for Localized Fat Treatment on Clinical and Psychological Outcomes: A Randomized, Single-Blind, Placebo-Controlled Clinical Trial.
Read more18 May 2020
publication
Remodeling of the Core Leads HIV-1 Preintegration Complex into the Nucleus of Human Lymphocytes.
Read more05 Feb 2020
publication
Anti-HIV-1 antibodies trigger non-lytic complement deposition on infected cells.
Read more30 Jan 2020
publication
Structure of the prefusion-locking broadly neutralizing antibody RVC20 bound to the rabies virus glycoprotein.
Read more06 Dec 2019
publication
X-ray Structures of the Post-fusion 6-Helix Bundle of the Human Syncytins and their Functional Implications.
Read more15 Oct 2019
18 Sep 2019
publication
Atlastin Endoplasmic Reticulum-Shaping Proteins Facilitate Zika Virus Replication.
Read more12 Jul 2019
publication
IFITM proteins inhibit placental syncytiotrophoblast formation and promote fetal demise.
Read more20 Jun 2019
publication
Proliferative memory SAMHD1low CD4+ T cells harbour high levels of HIV-1 with compartmentalized viral populations
Read more12 Jun 2019
01 Jun 2019
publication
Accelerated thymopoiesis and improved T-cell responses in HLA-A2/-DR2 transgenic BRGS-based human immune system mice.
Read more09 Apr 2019
publication
HIV-1 Envelope Recognition by Polyreactive and Cross-Reactive Intestinal B Cells
Read more08 Apr 2019
event
Groupe de Reflexion SIDA (GRS) seminar: “Determinants of HIV-1 broadly neutralizing antibody induction”
Read more04 Apr 2019
event
Department of Immunology seminar: Andrew Oberst, Too important to die: New antiviral roles for “cell death” pathways in the brain
Read more20 Feb 2019
18 Sep 2018
event
Groupe de Réflexion SIDA (GRS) seminar: “Defining Correlates of Immunology using Systems Serology”
Read more01 Sep 2018
01 Aug 2018
28 Jul 2018
29 May 2018
publication
Conformational Plasticity in Broadly Neutralizing HIV-1 Antibodies Triggers Polyreactivity
Read more20 Apr 2018
event
“Functional CURE under some ENIGMATIC mechanisms: Choke-and-Mute, rather than Shoot-and-Kill ?” by Jacques Leibowitch – VIROLOGY DEPARTMENT SEMINAR
Read more17 Apr 2018
event
“Disruptive Discoveries for HIV, HCV and HBV Infections” by Raymond Schinazi – Virology & Immunology departments joint seminar
Read more21 Nov 2017
publication
More than meets the I: the diverse antiviral and cellular functions of interferon-induced transmembrane proteins
Read more13 Oct 2017
publication
HIV Fusion in Dendritic Cells Occurs Mainly at the Surface and Is Limited by Low CD4 Levels
Read more23 Aug 2017
10 Jul 2017
publication
HEXIM1 and NEAT1 Long Non-coding RNA Form a Multi-subunit Complex that Regulates DNA-Mediated Innate Immune Response
Read more14 Jun 2017
publication
Zika virus induces massive cytoplasmic vacuolization and paraptosis-like death in infected cells.
Read more12 Jun 2017
15 Mar 2017
publication
CD32a is a marker of a CD4 T-cell HIV reservoir harbouring replication-competent proviruses
Read more15 Mar 2017
publication
Ultrasensitive HIV-1 p24 Assay Detects Single Infected Cells and Differences in Reservoir Induction by Latency Reversal Agents.
Read more09 Feb 2017
publication
Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement
Read more02 Feb 2017
25 Jan 2017
11 Jan 2017
publication
SUN2 silencing impairs CD4 T cell proliferation and alters sensitivity to HIV-1 infection independently of Cyclophilin A
Read more10 Jan 2017
publication
Axl Mediates ZIKA Virus Entry in Human Glial Cells and Modulates Innate Immune Responses.
Read more10 Oct 2016
publication
CD4-mimetic sulfopeptide conjugates display sub-nanomolar anti-HIV-1 activity and protect macaques against a SHIV162P3 vaginal challenge
Read more12 Sep 2016
06 Sep 2016
publication
Natural mutations in IFITM3 modulate post-translational regulation and toggle antiviral specificity
Read more30 Aug 2016
12 Jul 2016
10 Jun 2016
publication
HIV-Infected Dendritic Cells Present Endogenous MHC Class II-Restricted Antigens to HIV-Specific CD4+ T Cells
Read more12 May 2016
03 Mar 2016
03 Mar 2016
01 Mar 2016
12 Feb 2016
10 Feb 2016
05 Feb 2016
30 Oct 2015
publication
Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women
Read more14 Oct 2015
publication
The phosphatidylserine and phosphatidylethanolamine receptor CD300a binds dengue virus and enhances infection
Read more23 Sep 2015
14 Sep 2015
09 Sep 2015
project
REEMFOAMY : Human infection with zoonotic simian foamy retroviruses: role of virological and immunological factors in restricting viral emergence
Read more28 Aug 2015
publication
Inhibition of mTORC1 Enhances the Translation of Chikungunya Proteins via the Activation of the MnK/eIF4E Pathway
Read more25 Aug 2015
publication
Human Immunodeficiency Virus-1 Cell-To-Cell Transmission And Antiviral Strategies: An Overview
Read more05 Aug 2015
06 Jul 2015
01 Jul 2015
01 Jul 2015
publication
Plasmacytoid Dendritic Cell Infection and Sensing Capacity during Pathogenic and Nonpathogenic Simian Immunodeficiency Virus Infection.
Read more11 May 2015
13 Mar 2015
publication
Low SAMHD1 expression following T-cell activation and proliferation renders CD4+ T cells susceptible to HIV-1
Read more03 Mar 2015
publication
Viral entry route determines how human plasmacytoid dendritic cells produce type I interferons
Read more27 Jan 2015
publication
Nef promotes evasion of human immunodeficiency virus type 1-infected cells from the CTLA-4-mediated inhibition of T-cell activation
Read more13 Jan 2015
26 Nov 2014
12 Nov 2014
publication
Distinct characteristics of endometrial and decidual macrophages and regulation of their permissivity to HIV-1 infection by SAMHD1.
Read more13 Jun 2014
28 Mar 2014
publication
Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes.
Read more20 Feb 2014
publication
Plasmacytoid dendritic cells engagement by influenza vaccine as a surrogate strategy for driving T-helper type 1 responses in human neonatal settings
Read more25 Nov 2013
31 Oct 2013
publication
Identification of novel compounds inhibiting chikungunya virus-induced cell death by high throughput screening of a kinase inhibitor library
Read more18 Oct 2013
05 Sep 2013
publication
Real-time whole-body visualization of Chikungunya Virus infection and host interferon response in zebrafish.
Read more20 Aug 2013
30 Jul 2013
publication
HIV-1 Nef promotes the localization of Gag to the cell membrane and facilitates viral cell-to-cell transfer
Read more10 Jan 2013
publication
Neonatal plasmacytoid dendritic cells (pDCs) display subset variation but can elicit potent anti-viral innate responses
Read more26 Dec 2012
publication
SAMHD1 restricts HIV-1 cell-to-cell transmission and limits immune detection in monocyte-derived dendritic cells
Read more12 Oct 2012
publication
Subcapsular sinus macrophages promote NK cell accumulation and activation in response to lymph-borne viral particles
Read more28 Aug 2012
27 Jul 2012
publication
Chikungunya-induced cell death is limited by ER and oxidative stress-induced autophagy
Read more12 Jul 2012
15 May 2012
publication
Transcytosis of HTLV-1 across a tight human epithelial barrier and infection of subepithelial dendritic cells
Read more17 Apr 2012
16 Apr 2012
27 Feb 2012
publication
Cutting edge: independent roles for IRF-3 and IRF-7 in hematopoietic and nonhematopoietic cells during host response to Chikungunya infection
Read more16 Nov 2011
12 Aug 2011
publication
Automated genome-wide visual profiling of cellular proteins involved in HIV infection
Read more09 Mar 2011
publication
A new role for the HTLV-1 p8 protein: increasing intercellular conduits and viral cell-to-cell transmission
Read more17 Feb 2011
12 Aug 2010
01 Jul 2010
17 Jun 2010
10 Mar 2010
publication
Preclinical studies of a modified vaccinia virus Ankara-based HIV candidate vaccine: antigen presentation and antiviral effect
Read more15 Feb 2010
publication
Type I IFN controls chikungunya virus via its action on nonhematopoietic cells.
Read more28 Dec 2009
publication
The antiviral factor APOBEC3G improves CTL recognition of cultured HIV-infected T cells
Read more12 Aug 2009
publication
Partial inhibition of human immunodeficiency virus replication by type I interferons: impact of cell-to-cell viral transfer
Read more15 Apr 2009
publication
Simultaneous cell-to-cell transmission of human immunodeficiency virus to multiple targets through polysynapses
Read more05 Apr 2009
publication
Live attenuated measles vaccine expressing HIV-1 Gag virus like particles covered with gp160DeltaV1V2 is strongly immunogenic
Read more12 Dec 2007
publication
Pediatric measles vaccine expressing a dengue antigen induces durable serotype-specific neutralizing antibodies to dengue virus
Read more13 Jun 2007
01 Jun 2007
24 Mar 2007
01 Nov 2006
01 May 2006
publication
Human immunodeficiency virus type-1 infection impairs the formation of the immunological synapse
Read more01 May 2006
publication
DC-SIGN facilitates fusion of dendritic cells with human T-cell leukemia virus type 1-infected cells
Read more01 Jan 2006
15 Nov 2005
publication
DC-SIGN induction in alveolar macrophages defines privileged target host cells for mycobacteria in patients with tuberculosis
Read more01 Sep 2005
publication
Extensive editing of a small fraction of human T-cell leukemia virus type 1 genomes by four APOBEC3 cytidine deaminases
Read more01 May 2005
publication
Covert human immunodeficiency virus replication in dendritic cells and in DC-SIGN-expressing cells promotes long-term transmission to lymphocytes
Read more12 Apr 2004
publication
Identification of cryptic MHC I-restricted epitopes encoded by HIV-1 alternative reading frames
Read more01 Mar 2004
01 Jan 2004
publication
DC-SIGN from African green monkeys is expressed in lymph nodes and mediates infection in trans of simian immunodeficiency virus SIVagm.
Read more23 Oct 2003
01 May 2003
publication
Inhibition of human immunodeficiency virus type 1 Env-mediated fusion by DC-SIGN
Read more27 Feb 2003
publication
DC-SIGN and L-SIGN are high affinity binding receptors for hepatitis C virus glycoprotein E2
Read more01 Jan 2002
publication