Timeline

Olivier Schwartz
Head of Structure
07 Oct 2024
publication

Modeling memory B cell responses in a lymphoid organ-chip to evaluate mRNA vaccine boosting.

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26 Sep 2024
publication

Levels and functionality of Pacific Islanders’ hybrid humoral immune response to BNT162b2 vaccination and delta/omicron infection: A cohort study in New Caledonia.

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19 Jul 2024
publication

Broad sarbecovirus neutralization by combined memory B cell antibodies to ancestral SARS-CoV-2.

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21 Jun 2024
publication

Structural basis of TMPRSS2 zymogen activation and recognition by the HKU1 seasonal coronavirus.

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11 Jun 2024
publication

Dynamic label-free analysis of SARS-CoV-2 infection reveals virus-induced subcellular remodeling.

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13 Mar 2024
publication

Distinct evolution of SARS-CoV-2 Omicron XBB and BA.2.86/JN.1 lineages combining increased fitness and antibody evasion.

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13 Dec 2023
publication

High fusion and cytopathy of SARS-CoV-2 variant B.1.640.1.

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25 Oct 2023
publication

TMPRSS2 is a functional receptor for human coronavirus HKU1.

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09 Aug 2023
publication

Dissecting human population variation in single-cell responses to SARS-CoV-2

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14 Jun 2023
publication

Complement-dependent mpox-virus-neutralizing antibodies in infected and vaccinated individuals.

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01 Jun 2023
publication

Estimated protection against COVID-19 based on predicted neutralisation titres from multiple antibody measurements in a longitudinal cohort, France, April 2020 to November 2021.

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17 May 2023
event

40 years of HIV science

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28 Feb 2023
publication

Exposure to Secreted Bacterial Factors Promotes HIV-1 Replication in CD4+ T Cells.

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14 Feb 2023
publication

Resistance of Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 to neutralizing antibodies.

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25 Nov 2022
publication

Defective activation and regulation of type I interferon immunity is associated with increasing COVID-19 severity.

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17 Nov 2022
publication

Longitudinal analysis of serum neutralization of SARS-CoV-2 Omicron BA.2, BA.4, and BA.5 in patients receiving monoclonal antibodies.

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05 Oct 2022
publication

Duration of BA.5 neutralization in sera and nasal swabs from SARS-CoV-2 vaccinated individuals, with or without omicron breakthrough infection.

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01 Sep 2022
publication

Neutralising antibody responses to SARS-CoV-2 omicron among elderly nursing home residents following a booster dose of BNT162b2 vaccine: A community-based, prospective, longitudinal cohort study.

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27 Aug 2022
publication

IRF8 regulates efficacy of therapeutic anti-CD20 monoclonal antibodies.

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22 Jul 2022
publication

Tracking receptor motions at the plasma membrane reveals distinct effects of ligands on CCR5 dynamics depending on its dimerization status.

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15 Jul 2022
publication

Y RNAs are conserved endogenous RIG-I ligands across RNA virus infection and are targeted by HIV-1.

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15 Jul 2022
publication

C910 chemical compound inhibits the traffiking of several bacterial AB toxins with cross-protection against influenza virus.

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08 Jul 2022
publication

Kinetics of the SARS-CoV-2 Antibody Avidity Response Following Infection and Vaccination.

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04 Jul 2022
publication

Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2.

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17 Jun 2022
news

New publication – Potent Human Broadly SARS-CoV-2 Neutralizing IgA and IgG Antibodies Effective Against Omicron BA.1 and BA.2

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01 Jun 2022
publication

Serum neutralization of SARS-CoV-2 Omicron sublineages BA.1 and BA.2 in patients receiving monoclonal antibodies.

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04 May 2022
publication

Identification of DAXX as a restriction factor of SARS-CoV-2 through a CRISPR/Cas9 screen.

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11 Apr 2022
publication

Transient viral exposure drives functionally-coordinated humoral immune responses in HIV-1 post-treatment controllers.

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08 Apr 2022
news

New publication – Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller

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12 Mar 2022
publication

Fusogenicity and neutralization sensitivity of the SARS-CoV-2 Delta sublineage AY.4.2.

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07 Mar 2022
publication

Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller.

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25 Feb 2022
news

Seminar by Bob Seder on mRNA-1273 and mRNA-Omicron boost immune reponses

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02 Feb 2022
publication

Broadly neutralizing anti-HIV-1 antibodies tether viral particles at the surface of infected cells.

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01 Feb 2022
publication

Considerable escape of SARS-CoV-2 Omicron to antibody neutralization.

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26 Jan 2022
publication

Low CCR5 expression protects HIV-specific CD4+ T cells of elite controllers from viral entry.

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01 Jan 2022
publication

Robust and Functional Immune Memory Up to 9 Months After SARS-CoV-2 Infection: A Southeast Asian Longitudinal Cohort.

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01 Nov 2021
publication

Release of infectious virus and cytokines in nasopharyngeal swabs from individuals infected with non-alpha or alpha SARS-CoV-2 variants: an observational retrospective study.

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17 Sep 2021
publication

Sex Differences in the Evolution of Neutralizing Antibodies to Severe Acute Respiratory Syndrome Coronavirus 2.

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01 Sep 2021
publication

Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection.

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18 Aug 2021
news

Immune checkpoint inhibitors improve cellular immunity against SARS-CoV-2 infection

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18 Aug 2021
publication

Bystander CD4 T-cell death is inhibited by broadly neutralizing anti-HIV antibodies only at levels blocking cell-to-cell viral transmission.

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14 Aug 2021
publication

A monocyte/dendritic cell molecular signature of SARS-CoV-2 related multisystem inflammatory syndrome in children (MIS-C) with severe myocarditis.

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01 Aug 2021
publication

Transmission of SARS-CoV-2 Alpha Variant (B.1.1.7) From a BNT162b2-Vaccinated Individual.

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01 Aug 2021
publication

Immune checkpoint inhibitors increase T cell immunity during SARS-CoV-2 infection.

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30 Jul 2021
publication

Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2.

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28 Jul 2021
publication

SUMOylation of SAMHD1 at Lysine 595 is required for HIV-1 restriction in non-cycling cells.

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22 Jul 2021
news

SARS-CoV-2 : induces the dedifferentiation of multiciliated cells and impairs mucociliary clearance

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14 Jul 2021
publication

Analysis of T cell responses directed against the spike and/or membrane and/or nucleocapsid proteins in chilblain-like lesions patients during the COVID-19 pandemic.

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08 Jul 2021
publication

Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization.

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02 Jul 2021
publication

Pregnancy complications and Interferon-induced transmembrane proteins (IFITM): balancing antiviral immunity and placental development.

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11 Jun 2021
news

COVID-19: sensitivity of the Indian variant (B.1.617.2) to monoclonal antibodies and sera from convalescent and vaccinated individuals

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18 May 2021
publication

Asymptomatic and symptomatic SARS-CoV-2 infections elicit polyfunctional antibodies.

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01 Apr 2021
publication

SARS-CoV-2 infection in schools in a northern French city: a retrospective serological cohort study in an area of high transmission, France, January to April 2020

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08 Feb 2021
publication

Rapid decline of neutralizing antibodies against SARS-CoV-2 among infected healthcare workers.

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01 Feb 2021
publication

Syncytia formation by SARS-CoV-2-infected cells.

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20 Jan 2021
publication

IgA dominates the early neutralizing antibody response to SARS-CoV-2.

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01 Jan 2021
publication

Characteristics Associated with Olfactory and Taste Disorders in COVID-19.

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01 Dec 2020
publication

Syncytia formation by SARS-CoV-2-infected cells.

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20 Oct 2020
publication

Antibody Neutralization of HIV-1 Crossing the Blood-Brain Barrier.

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09 Sep 2020
project

ZIKA

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02 Sep 2020
publication

A comparison of four serological assays for detecting anti–SARS-CoV-2 antibodies in human serum samples from different populations

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01 Sep 2020
publication

Serologic responses to SARS-CoV-2 infection among hospital staff with mild disease in eastern France.

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01 Jun 2020
publication

Efficacy of Ultrasound for Localized Fat Treatment on Clinical and Psychological Outcomes: A Randomized, Single-Blind, Placebo-Controlled Clinical Trial.

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18 May 2020
publication

Remodeling of the Core Leads HIV-1 Preintegration Complex into the Nucleus of Human Lymphocytes.

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05 Feb 2020
publication

Anti-HIV-1 antibodies trigger non-lytic complement deposition on infected cells.

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30 Jan 2020
publication

Structure of the prefusion-locking broadly neutralizing antibody RVC20 bound to the rabies virus glycoprotein.

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06 Dec 2019
publication

X-ray Structures of the Post-fusion 6-Helix Bundle of the Human Syncytins and their Functional Implications.

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01 Dec 2019
publication

The Atlastin ER-shaping proteins facilitate Zika virus replication

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15 Oct 2019
project

3D Pasteur

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12 Jul 2019
publication

IFITM proteins inhibit placental syncytiotrophoblast formation and promote fetal demise.

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20 Jun 2019
publication

Proliferative memory SAMHD1low CD4+ T cells harbour high levels of HIV-1 with compartmentalized viral populations

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12 Jun 2019
publication

HIV-1 Envelope FRETted Over by Antibodies

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01 Jun 2019
publication

Accelerated thymopoiesis and improved T-cell responses in HLA-A2/-DR2 transgenic BRGS-based human immune system mice.

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09 Apr 2019
publication

HIV-1 Envelope Recognition by Polyreactive and Cross-Reactive Intestinal B Cells

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08 Apr 2019
event

Groupe de Reflexion SIDA (GRS) seminar: “Determinants of HIV-1 broadly neutralizing antibody induction”

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04 Apr 2019
event

Department of Immunology seminar: Andrew Oberst, Too important to die: New antiviral roles for “cell death” pathways in the brain

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20 Feb 2019
event

130 Years of Institut Pasteur: Celebrating Science

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18 Sep 2018
event

Groupe de Réflexion SIDA (GRS) seminar: “Defining Correlates of Immunology using Systems Serology”

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01 Sep 2018
publication

Markers of the HIV-1 reservoir: facts and controversies

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01 Aug 2018
publication

A human immune system mouse model with robust lymph node development.

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28 Jul 2018
publication

HIV-1 cell-to-cell transmission and broadly neutralizing antibodies

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29 May 2018
publication

Conformational Plasticity in Broadly Neutralizing HIV-1 Antibodies Triggers Polyreactivity

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20 Apr 2018
event

“Functional CURE under some ENIGMATIC mechanisms: Choke-and-Mute, rather than Shoot-and-Kill ?” by Jacques Leibowitch – VIROLOGY DEPARTMENT SEMINAR

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17 Apr 2018
event

“Disruptive Discoveries for HIV, HCV and HBV Infections” by Raymond Schinazi – Virology & Immunology departments joint seminar

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21 Nov 2017
publication

More than meets the I: the diverse antiviral and cellular functions of interferon-induced transmembrane proteins

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13 Oct 2017
publication

HIV Fusion in Dendritic Cells Occurs Mainly at the Surface and Is Limited by Low CD4 Levels

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23 Aug 2017
publication

IFITM3 requires an amphipathic helix for antiviral activity

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10 Jul 2017
publication

HEXIM1 and NEAT1 Long Non-coding RNA Form a Multi-subunit Complex that Regulates DNA-Mediated Innate Immune Response

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14 Jun 2017
publication

Zika virus induces massive cytoplasmic vacuolization and paraptosis-like death in infected cells.

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12 Jun 2017
news

Le virus Zika modifie la morphologie des cellules jusqu’à l’implosion

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15 Mar 2017
publication

CD32a is a marker of a CD4 T-cell HIV reservoir harbouring replication-competent proviruses

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15 Mar 2017
publication

Ultrasensitive HIV-1 p24 Assay Detects Single Infected Cells and Differences in Reservoir Induction by Latency Reversal Agents.

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09 Feb 2017
publication

Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement

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02 Feb 2017
publication

They Might Be Giants: Does Syncytium Formation Sink or Spread HIV Infection?

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25 Jan 2017
publication

Lack of ADCC Breadth of Human Nonneutralizing Anti-HIV-1 Antibodies

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11 Jan 2017
publication

SUN2 silencing impairs CD4 T cell proliferation and alters sensitivity to HIV-1 infection independently of Cyclophilin A

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10 Jan 2017
publication

Axl Mediates ZIKA Virus Entry in Human Glial Cells and Modulates Innate Immune Responses.

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10 Oct 2016
publication

CD4-mimetic sulfopeptide conjugates display sub-nanomolar anti-HIV-1 activity and protect macaques against a SHIV162P3 vaginal challenge

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12 Sep 2016
publication

[Antibodies that kill HIV-1-infected cells]

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06 Sep 2016
publication

Natural mutations in IFITM3 modulate post-translational regulation and toggle antiviral specificity

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30 Aug 2016
news

VIROLOGY AND IMMUNOLOGY JOINT SEMINAR

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12 Jul 2016
publication

[A mystery solved: HIV-1 Nef targets SERINC3 and SERINC5]

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10 Jun 2016
publication

HIV-Infected Dendritic Cells Present Endogenous MHC Class II-Restricted Antigens to HIV-Specific CD4+ T Cells

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12 May 2016
event

VIROLOGY DEPARTMENT SEMINAR

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03 Mar 2016
news

Antibodies capable of eliminating HIV-infected cells

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03 Mar 2016
publication

Elimination of HIV-1-infected cells by broadly neutralizing antibodies

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01 Mar 2016
publication

Actin’ on HIV: How Dendritic Cells Spread Infection

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12 Feb 2016
project

Group for AIDS Research

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10 Feb 2016
publication

SUN2 Overexpression Deforms Nuclear Shape and Inhibits HIV.

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05 Feb 2016
publication

La famille des protéines IFITM : effets antiviraux et fonctions cellulaires

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30 Oct 2015
publication

Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women

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14 Oct 2015
publication

The phosphatidylserine and phosphatidylethanolamine receptor CD300a binds dengue virus and enhances infection

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23 Sep 2015
publication

Vpr Enhances Tumor Necrosis Factor Production by HIV-1-Infected T Cells

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14 Sep 2015
project

HIV signature on RIG-I-like receptors

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09 Sep 2015
project

REEMFOAMY : Human infection with zoonotic simian foamy retroviruses: role of virological and immunological factors in restricting viral emergence

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28 Aug 2015
publication

Inhibition of mTORC1 Enhances the Translation of Chikungunya Proteins via the Activation of the MnK/eIF4E Pathway

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25 Aug 2015
publication

Human Immunodeficiency Virus-1 Cell-To-Cell Transmission And Antiviral Strategies: An Overview

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05 Aug 2015
project

HIV

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06 Jul 2015
project

CHIKUNGUNYA VIRUS

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01 Jul 2015
publication

SAMHD1 Limits HIV-1 Antigen Presentation by Monocyte-Derived Dendritic Cells

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01 Jul 2015
publication

Plasmacytoid Dendritic Cell Infection and Sensing Capacity during Pathogenic and Nonpathogenic Simian Immunodeficiency Virus Infection.

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11 May 2015
team

Virus and Immunity

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13 Mar 2015
publication

Low SAMHD1 expression following T-cell activation and proliferation renders CD4+ T cells susceptible to HIV-1

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03 Mar 2015
publication

Viral entry route determines how human plasmacytoid dendritic cells produce type I interferons

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27 Jan 2015
publication

Nef promotes evasion of human immunodeficiency virus type 1-infected cells from the CTLA-4-mediated inhibition of T-cell activation

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13 Jan 2015
publication

HIV-2 infects resting CD4+ T cells but not monocyte-derived dendritic cells

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26 Nov 2014
publication

IFITM proteins incorporated into HIV-1 virions impair viral fusion and spread

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12 Nov 2014
publication

Distinct characteristics of endometrial and decidual macrophages and regulation of their permissivity to HIV-1 infection by SAMHD1.

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13 Jun 2014
publication

[HIV-1 cell-to-cell transmission and broadly neutralizing antibodies]

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28 Mar 2014
publication

Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes.

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20 Feb 2014
publication

Plasmacytoid dendritic cells engagement by influenza vaccine as a surrogate strategy for driving T-helper type 1 responses in human neonatal settings

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25 Nov 2013
publication

Broadly neutralizing antibodies that inhibit HIV-1 cell to cell transmission

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31 Oct 2013
publication

Identification of novel compounds inhibiting chikungunya virus-induced cell death by high throughput screening of a kinase inhibitor library

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18 Oct 2013
publication

Gain-of-function research: unknown risks

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05 Sep 2013
publication

Real-time whole-body visualization of Chikungunya Virus infection and host interferon response in zebrafish.

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20 Aug 2013
publication

The SAMHD1 knockout mouse model: in vivo veritas?

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30 Jul 2013
publication

HIV-1 Nef promotes the localization of Gag to the cell membrane and facilitates viral cell-to-cell transfer

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10 Jan 2013
publication

Neonatal plasmacytoid dendritic cells (pDCs) display subset variation but can elicit potent anti-viral innate responses

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26 Dec 2012
publication

SAMHD1 restricts HIV-1 cell-to-cell transmission and limits immune detection in monocyte-derived dendritic cells

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12 Oct 2012
publication

Subcapsular sinus macrophages promote NK cell accumulation and activation in response to lymph-borne viral particles

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28 Aug 2012
publication

Restricting HIV the SAMHD1 way: through nucleotide starvation

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27 Jul 2012
publication

Chikungunya-induced cell death is limited by ER and oxidative stress-induced autophagy

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12 Jul 2012
publication

Hyperthermia stimulates HIV-1 replication

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15 May 2012
publication

Transcytosis of HTLV-1 across a tight human epithelial barrier and infection of subepithelial dendritic cells

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17 Apr 2012
publication

[Generalized eruptive syringoma]

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16 Apr 2012
publication

Chikungunya virus-induced autophagy delays caspase-dependent cell death

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27 Feb 2012
publication

Cutting edge: independent roles for IRF-3 and IRF-7 in hematopoietic and nonhematopoietic cells during host response to Chikungunya infection

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16 Nov 2011
publication

Innate sensing of foamy viruses by human hematopoietic cells

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12 Aug 2011
publication

Automated genome-wide visual profiling of cellular proteins involved in HIV infection

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09 Mar 2011
publication

A new role for the HTLV-1 p8 protein: increasing intercellular conduits and viral cell-to-cell transmission

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17 Feb 2011
publication

Innate sensing of HIV-infected cells

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12 Aug 2010
publication

HIV-1 Virological Synapse: Live Imaging of Transmission

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01 Jul 2010
publication

Biology and pathogenesis of chikungunya virus

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17 Jun 2010
publication

Tetherin restricts productive HIV-1 cell-to-cell transmission

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10 Mar 2010
publication

Preclinical studies of a modified vaccinia virus Ankara-based HIV candidate vaccine: antigen presentation and antiviral effect

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15 Feb 2010
publication

Type I IFN controls chikungunya virus via its action on nonhematopoietic cells.

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28 Dec 2009
publication

The antiviral factor APOBEC3G improves CTL recognition of cultured HIV-infected T cells

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12 Aug 2009
publication

Partial inhibition of human immunodeficiency virus replication by type I interferons: impact of cell-to-cell viral transfer

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15 Apr 2009
publication

Simultaneous cell-to-cell transmission of human immunodeficiency virus to multiple targets through polysynapses

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05 Apr 2009
publication

Live attenuated measles vaccine expressing HIV-1 Gag virus like particles covered with gp160DeltaV1V2 is strongly immunogenic

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12 Dec 2007
publication

Pediatric measles vaccine expressing a dengue antigen induces durable serotype-specific neutralizing antibodies to dengue virus

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13 Jun 2007
publication

Human muscle satellite cells as targets of Chikungunya virus infection

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01 Jun 2007
publication

Characterization of reemerging chikungunya virus

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24 Mar 2007
publication

Modulation of the immunological synapse: a key to HIV-1 pathogenesis?

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01 Nov 2006
publication

Inefficient human immunodeficiency virus replication in mobile lymphocytes

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01 May 2006
publication

DC-SIGN facilitates fusion of dendritic cells with human T-cell leukemia virus type 1-infected cells

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01 May 2006
publication

Human immunodeficiency virus type-1 infection impairs the formation of the immunological synapse

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01 Jan 2006
publication

Restriction of foamy viruses by APOBEC cytidine deaminases

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15 Nov 2005
publication

DC-SIGN induction in alveolar macrophages defines privileged target host cells for mycobacteria in patients with tuberculosis

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01 Sep 2005
publication

Extensive editing of a small fraction of human T-cell leukemia virus type 1 genomes by four APOBEC3 cytidine deaminases

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01 May 2005
publication

Covert human immunodeficiency virus replication in dendritic cells and in DC-SIGN-expressing cells promotes long-term transmission to lymphocytes

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12 Apr 2004
publication

Identification of cryptic MHC I-restricted epitopes encoded by HIV-1 alternative reading frames

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01 Mar 2004
publication

Cell of the month. Dendritic cell sensing a lymphocyte

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01 Jan 2004
publication

DC-SIGN from African green monkeys is expressed in lymph nodes and mediates infection in trans of simian immunodeficiency virus SIVagm.

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23 Oct 2003
publication

DC-SIGN promotes exogenous MHC-I-restricted HIV-1 antigen presentation

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01 May 2003
publication

Inhibition of human immunodeficiency virus type 1 Env-mediated fusion by DC-SIGN

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27 Feb 2003
publication

DC-SIGN and L-SIGN are high affinity binding receptors for hepatitis C virus glycoprotein E2

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01 Jan 2002
publication

HIV-1 Nef-induced upregulation of DC-SIGN in dendritic cells promotes lymphocyte clustering and viral spread

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