Timeline

Olivier Schwartz
Head of Structure
08 Apr 2019
event

Groupe de Reflexion SIDA (GRS) seminar: “Determinants of HIV-1 broadly neutralizing antibody induction”

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04 Apr 2019
event

Department of Immunology seminar: Andrew Oberst, Too important to die: New antiviral roles for “cell death” pathways in the brain

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19 Mar 2019
publication

Accelerated thymopoiesis and improved T cell responses in HLA-A2/-DR2 transgenic BRGS-based human immune system mice

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20 Feb 2019
event

130 Years of Institut Pasteur: Celebrating Science

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18 Sep 2018
event

Groupe de Réflexion SIDA (GRS) seminar: “Defining Correlates of Immunology using Systems Serology”

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01 Sep 2018
publication

Markers of the HIV-1 reservoir: facts and controversies

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31 Jul 2018
publication

A human immune system mouse model with robust lymph node development

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28 Jul 2018
publication

HIV-1 cell-to-cell transmission and broadly neutralizing antibodies

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29 May 2018
publication

Conformational Plasticity in Broadly Neutralizing HIV-1 Antibodies Triggers Polyreactivity

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08 May 2018
publication

TIM-1 Ubiquitination Mediates Dengue Virus Entry

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20 Apr 2018
event

“Functional CURE under some ENIGMATIC mechanisms: Choke-and-Mute, rather than Shoot-and-Kill ?” by Jacques Leibowitch – VIROLOGY DEPARTMENT SEMINAR

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17 Apr 2018
event

“Disruptive Discoveries for HIV, HCV and HBV Infections” by Raymond Schinazi – Virology & Immunology departments joint seminar

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21 Nov 2017
publication

More than meets the I: the diverse antiviral and cellular functions of interferon-induced transmembrane proteins

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13 Oct 2017
publication

HIV Fusion in Dendritic Cells Occurs Mainly at the Surface and Is Limited by Low CD4 Levels

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23 Aug 2017
publication

IFITM3 requires an amphipathic helix for antiviral activity

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10 Jul 2017
publication

HEXIM1 and NEAT1 Long Non-coding RNA Form a Multi-subunit Complex that Regulates DNA-Mediated Innate Immune Response

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12 Jun 2017
news

Le virus Zika modifie la morphologie des cellules jusqu’à l’implosion

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04 May 2017
publication

Zika virus induces massive cytoplasmic vacuolization and paraptosis-like death in infected cells

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15 Mar 2017
publication

CD32a is a marker of a CD4 T-cell HIV reservoir harbouring replication-competent proviruses

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28 Feb 2017
publication

Ultrasensitive HIV-1 p24 Assay Detects Single Infected Cells and Differences in Reservoir Induction by Latency Reversal Agents

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21 Feb 2017
publication

Respiratory Syncytial Virus Infects Regulatory B Cells in Human Neonates via Chemokine Receptor CX3CR1 and Promotes Lung Disease Severity

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09 Feb 2017
publication

Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement

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02 Feb 2017
publication

They Might Be Giants: Does Syncytium Formation Sink or Spread HIV Infection?

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25 Jan 2017
publication

Lack of ADCC Breadth of Human Nonneutralizing Anti-HIV-1 Antibodies

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11 Jan 2017
publication

SUN2 silencing impairs CD4 T cell proliferation and alters sensitivity to HIV-1 infection independently of Cyclophilin A

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10 Jan 2017
publication

Axl Mediates ZIKA Virus Entry in Human Glial Cells and Modulates Innate Immune Responses

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10 Oct 2016
publication

CD4-mimetic sulfopeptide conjugates display sub-nanomolar anti-HIV-1 activity and protect macaques against a SHIV162P3 vaginal challenge

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12 Sep 2016
publication

[Antibodies that kill HIV-1-infected cells]

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06 Sep 2016
publication

Natural mutations in IFITM3 modulate post-translational regulation and toggle antiviral specificity

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30 Aug 2016
news

VIROLOGY AND IMMUNOLOGY JOINT SEMINAR

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12 Jul 2016
publication

[A mystery solved: HIV-1 Nef targets SERINC3 and SERINC5]

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10 Jun 2016
publication

HIV-Infected Dendritic Cells Present Endogenous MHC Class II-Restricted Antigens to HIV-Specific CD4+ T Cells

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12 May 2016
event

VIROLOGY DEPARTMENT SEMINAR

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03 Mar 2016
news

Antibodies capable of eliminating HIV-infected cells

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03 Mar 2016
publication

Elimination of HIV-1-infected cells by broadly neutralizing antibodies

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01 Mar 2016
publication

Actin’ on HIV: How Dendritic Cells Spread Infection

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12 Feb 2016
project

Group for AIDS Research

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10 Feb 2016
publication

SUN2 overexpression deforms nuclear shape and inhibits HIV

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05 Feb 2016
publication

La famille des protéines IFITM : effets antiviraux et fonctions cellulaires

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30 Oct 2015
publication

Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women

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14 Oct 2015
publication

The phosphatidylserine and phosphatidylethanolamine receptor CD300a binds dengue virus and enhances infection

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23 Sep 2015
publication

Vpr Enhances Tumor Necrosis Factor Production by HIV-1-Infected T Cells

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14 Sep 2015
project

HIV signature on RIG-I-like receptors

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09 Sep 2015
project

REEMFOAMY : Human infection with zoonotic simian foamy retroviruses: role of virological and immunological factors in restricting viral emergence

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28 Aug 2015
publication

Inhibition of mTORC1 Enhances the Translation of Chikungunya Proteins via the Activation of the MnK/eIF4E Pathway

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25 Aug 2015
publication

Human Immunodeficiency Virus-1 Cell-To-Cell Transmission And Antiviral Strategies: An Overview

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05 Aug 2015
project

HIV

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06 Jul 2015
project

CHIKUNGUNYA VIRUS

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01 Jul 2015
publication

SAMHD1 Limits HIV-1 Antigen Presentation by Monocyte-Derived Dendritic Cells

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11 May 2015
team

Virus and Immunity

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22 Apr 2015
publication

Plasmacytoid Dendritic Cell Infection and Sensing Capacity during Pathogenic and Nonpathogenic Simian Immunodeficiency Virus Infection

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13 Mar 2015
publication

Low SAMHD1 expression following T-cell activation and proliferation renders CD4+ T cells susceptible to HIV-1

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03 Mar 2015
publication

Viral entry route determines how human plasmacytoid dendritic cells produce type I interferons

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27 Jan 2015
publication

Nef promotes evasion of human immunodeficiency virus type 1-infected cells from the CTLA-4-mediated inhibition of T-cell activation

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13 Jan 2015
publication

HIV-2 infects resting CD4+ T cells but not monocyte-derived dendritic cells

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26 Nov 2014
publication

IFITM proteins incorporated into HIV-1 virions impair viral fusion and spread

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12 Nov 2014
publication

Distinct characteristics of endometrial and decidual macrophages and regulation of their permissivity to HIV-1 infection by SAMHD1

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13 Jun 2014
publication

[HIV-1 cell-to-cell transmission and broadly neutralizing antibodies]

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28 Mar 2014
publication

Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes

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20 Feb 2014
publication

Plasmacytoid dendritic cells engagement by influenza vaccine as a surrogate strategy for driving T-helper type 1 responses in human neonatal settings

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29 Jan 2014
publication

Large-scale nucleotide optimization of simian immunodeficiency virus reduces its capacity to stimulate type I interferon in vitro

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25 Nov 2013
publication

Broadly neutralizing antibodies that inhibit HIV-1 cell to cell transmission

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31 Oct 2013
publication

Identification of novel compounds inhibiting chikungunya virus-induced cell death by high throughput screening of a kinase inhibitor library

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18 Oct 2013
publication

Gain-of-function research: unknown risks

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05 Sep 2013
publication

Real-time whole-body visualization of Chikungunya Virus infection and host interferon response in zebrafish

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20 Aug 2013
publication

The SAMHD1 knockout mouse model: in vivo veritas?

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30 Jul 2013
publication

HIV-1 Nef promotes the localization of Gag to the cell membrane and facilitates viral cell-to-cell transfer

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10 Jan 2013
publication

Neonatal plasmacytoid dendritic cells (pDCs) display subset variation but can elicit potent anti-viral innate responses

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26 Dec 2012
publication

SAMHD1 restricts HIV-1 cell-to-cell transmission and limits immune detection in monocyte-derived dendritic cells

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12 Oct 2012
publication

Subcapsular sinus macrophages promote NK cell accumulation and activation in response to lymph-borne viral particles

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28 Aug 2012
publication

Restricting HIV the SAMHD1 way: through nucleotide starvation

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27 Jul 2012
publication

Chikungunya-induced cell death is limited by ER and oxidative stress-induced autophagy

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12 Jul 2012
publication

Hyperthermia stimulates HIV-1 replication

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15 May 2012
publication

Transcytosis of HTLV-1 across a tight human epithelial barrier and infection of subepithelial dendritic cells

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17 Apr 2012
publication

[Generalized eruptive syringoma]

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16 Apr 2012
publication

Chikungunya virus-induced autophagy delays caspase-dependent cell death

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27 Feb 2012
publication

Cutting edge: independent roles for IRF-3 and IRF-7 in hematopoietic and nonhematopoietic cells during host response to Chikungunya infection

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16 Nov 2011
publication

Innate sensing of foamy viruses by human hematopoietic cells

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12 Aug 2011
publication

Automated genome-wide visual profiling of cellular proteins involved in HIV infection

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09 Mar 2011
publication

A new role for the HTLV-1 p8 protein: increasing intercellular conduits and viral cell-to-cell transmission

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17 Feb 2011
publication

Innate sensing of HIV-infected cells

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12 Aug 2010
publication

HIV-1 Virological Synapse: Live Imaging of Transmission

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01 Jul 2010
publication

Biology and pathogenesis of chikungunya virus

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17 Jun 2010
publication

Tetherin restricts productive HIV-1 cell-to-cell transmission

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10 Mar 2010
publication

Preclinical studies of a modified vaccinia virus Ankara-based HIV candidate vaccine: antigen presentation and antiviral effect

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01 Feb 2010
publication

Type I IFN controls chikungunya virus via its action on nonhematopoietic cells

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28 Dec 2009
publication

The antiviral factor APOBEC3G improves CTL recognition of cultured HIV-infected T cells

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16 Dec 2009
publication

HIV-1 Nef inhibits ruffles, induces filopodia, and modulates migration of infected lymphocytes

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12 Aug 2009
publication

Partial inhibition of human immunodeficiency virus replication by type I interferons: impact of cell-to-cell viral transfer

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15 Apr 2009
publication

Simultaneous cell-to-cell transmission of human immunodeficiency virus to multiple targets through polysynapses

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05 Apr 2009
publication

Live attenuated measles vaccine expressing HIV-1 Gag virus like particles covered with gp160DeltaV1V2 is strongly immunogenic

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12 Dec 2007
publication

Pediatric measles vaccine expressing a dengue antigen induces durable serotype-specific neutralizing antibodies to dengue virus

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13 Jun 2007
publication

Human muscle satellite cells as targets of Chikungunya virus infection

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01 Jun 2007
publication

Characterization of reemerging chikungunya virus

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24 Mar 2007
publication

Modulation of the immunological synapse: a key to HIV-1 pathogenesis?

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12 Mar 2007
publication

A novel pathway down-modulating T cell activation involves HPK-1-dependent recruitment of 14-3-3 proteins on SLP-76

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11 Jan 2007
publication

ZAP-70 kinase regulates HIV cell-to-cell spread and virological synapse formation

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01 Nov 2006
publication

Inefficient human immunodeficiency virus replication in mobile lymphocytes

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01 May 2006
publication

Human immunodeficiency virus type-1 infection impairs the formation of the immunological synapse

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01 May 2006
publication

DC-SIGN facilitates fusion of dendritic cells with human T-cell leukemia virus type 1-infected cells

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01 Jan 2006
publication

Restriction of foamy viruses by APOBEC cytidine deaminases

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15 Nov 2005
publication

DC-SIGN induction in alveolar macrophages defines privileged target host cells for mycobacteria in patients with tuberculosis

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01 Sep 2005
publication

Extensive editing of a small fraction of human T-cell leukemia virus type 1 genomes by four APOBEC3 cytidine deaminases

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01 May 2005
publication

Covert human immunodeficiency virus replication in dendritic cells and in DC-SIGN-expressing cells promotes long-term transmission to lymphocytes

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12 Apr 2004
publication

Identification of cryptic MHC I-restricted epitopes encoded by HIV-1 alternative reading frames

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01 Mar 2004
publication

Cell of the month. Dendritic cell sensing a lymphocyte

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01 Jan 2004
publication

DC-SIGN from African green monkeys is expressed in lymph nodes and mediates infection in trans of simian immunodeficiency virus SIVagm

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23 Oct 2003
publication

DC-SIGN promotes exogenous MHC-I-restricted HIV-1 antigen presentation

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01 May 2003
publication

Inhibition of human immunodeficiency virus type 1 Env-mediated fusion by DC-SIGN

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27 Feb 2003
publication

DC-SIGN and L-SIGN are high affinity binding receptors for hepatitis C virus glycoprotein E2

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01 Jan 2002
publication

HIV-1 Nef-induced upregulation of DC-SIGN in dendritic cells promotes lymphocyte clustering and viral spread

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