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© Research
Publication : The British journal of dermatology

Analysis of T cell responses directed against the spike and/or membrane and/or nucleocapsid proteins in chilblain-like lesions patients during the COVID-19 pandemic.

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in The British journal of dermatology - 14 Jul 2021

Cassius C, Merandet M, Frumholtz L, Bergerat D, Samri A, Grolleau C, Grzelak L, Schwartz O, Yatim N, Moghadam P, Jaume L, Bagot M, Legoff J, Delaugerre C, Bouaziz JD, Le Buanec H, ,

Link to Pubmed [PMID] – 34258762

Link to DOI – 10.1111/bjd.20647

Br J Dermatol 2021 Jul; ():

A range of cutaneous manifestations has been described in association with severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) infection during the coronavirus disease 2019 (COVID-19) pandemic 1 . Among them, chilblain like lesions (CLL) occurred more frequently than expected. A direct link was demonstrated thanks to the visualization of viral particles in the skin endothelial cells by electron microscopy 2 which was further questioned 3 . An indirect link was highlighted with high prevalence of seropositivity in CLL patients compared to general population 4 .