Ligne de temps
Olivier Schwartz
Responsable de Structure
13 mars 2024
publication
Distinct evolution of SARS-CoV-2 Omicron XBB and BA.2.86/JN.1 lineages combining increased fitness and antibody evasion.
Lire plus13 déc. 2023
25 oct. 2023
09 août 2023
14 juin 2023
publication
Complement-dependent mpox-virus-neutralizing antibodies in infected and vaccinated individuals.
Lire plus01 juin 2023
publication
Estimated protection against COVID-19 based on predicted neutralisation titres from multiple antibody measurements in a longitudinal cohort, France, April 2020 to November 2021.
Lire plus17 mai 2023
28 févr. 2023
publication
Exposure to Secreted Bacterial Factors Promotes HIV-1 Replication in CD4+ T Cells.
Lire plus14 févr. 2023
publication
Resistance of Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 to neutralizing antibodies.
Lire plus25 nov. 2022
publication
Defective activation and regulation of type I interferon immunity is associated with increasing COVID-19 severity.
Lire plus17 nov. 2022
publication
Longitudinal analysis of serum neutralization of SARS-CoV-2 Omicron BA.2, BA.4, and BA.5 in patients receiving monoclonal antibodies.
Lire plus05 oct. 2022
publication
Duration of BA.5 neutralization in sera and nasal swabs from SARS-CoV-2 vaccinated individuals, with or without omicron breakthrough infection.
Lire plus01 sept. 2022
publication
Neutralising antibody responses to SARS-CoV-2 omicron among elderly nursing home residents following a booster dose of BNT162b2 vaccine: A community-based, prospective, longitudinal cohort study.
Lire plus27 août 2022
22 juil. 2022
publication
Tracking receptor motions at the plasma membrane reveals distinct effects of ligands on CCR5 dynamics depending on its dimerization status.
Lire plus15 juil. 2022
publication
Y RNAs are conserved endogenous RIG-I ligands across RNA virus infection and are targeted by HIV-1
Lire plus15 juil. 2022
publication
C910 chemical compound inhibits the traffiking of several bacterial AB toxins with cross-protection against influenza virus.
Lire plus08 juil. 2022
publication
Kinetics of the SARS-CoV-2 Antibody Avidity Response Following Infection and Vaccination.
Lire plus04 juil. 2022
publication
Potent human broadly SARS-CoV-2-neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2.
Lire plus17 juin 2022
news
New publication – Potent Human Broadly SARS-CoV-2 Neutralizing IgA and IgG Antibodies Effective Against Omicron BA.1 and BA.2
Lire plus01 juin 2022
publication
Serum neutralization of SARS-CoV-2 Omicron sublineages BA.1 and BA.2 in patients receiving monoclonal antibodies.
Lire plus04 mai 2022
publication
Identification of DAXX as a restriction factor of SARS-CoV-2 through a CRISPR/Cas9 screen.
Lire plus11 avr. 2022
publication
Transient viral exposure drives functionally-coordinated humoral immune responses in HIV-1 post-treatment controllers.
Lire plus08 avr. 2022
news
New publication – Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller
Lire plus12 mars 2022
publication
Fusogenicity and neutralization sensitivity of the SARS-CoV-2 Delta sublineage AY.4.2.
Lire plus07 mars 2022
publication
Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller.
Lire plus25 févr. 2022
02 févr. 2022
publication
Broadly neutralizing anti-HIV-1 antibodies tether viral particles at the surface of infected cells.
Lire plus01 févr. 2022
26 janv. 2022
publication
Low CCR5 expression protects HIV-specific CD4+ T cells of elite controllers from viral entry.
Lire plus01 janv. 2022
publication
Robust and Functional Immune Memory Up to 9 Months After SARS-CoV-2 Infection: A Southeast Asian Longitudinal Cohort.
Lire plus01 nov. 2021
publication
Release of infectious virus and cytokines in nasopharyngeal swabs from individuals infected with non-alpha or alpha SARS-CoV-2 variants: an observational retrospective study.
Lire plus17 sept. 2021
publication
Sex Differences in the Evolution of Neutralizing Antibodies to Severe Acute Respiratory Syndrome Coronavirus 2.
Lire plus01 sept. 2021
publication
Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection.
Lire plus18 août 2021
18 août 2021
publication
Bystander CD4 T-cell death is inhibited by broadly neutralizing anti-HIV antibodies only at levels blocking cell-to-cell viral transmission.
Lire plus14 août 2021
publication
A monocyte/dendritic cell molecular signature of SARS-CoV-2 related multisystem inflammatory syndrome in children (MIS-C) with severe myocarditis.
Lire plus01 août 2021
publication
Transmission of SARS-CoV-2 Alpha Variant (B.1.1.7) From a BNT162b2-Vaccinated Individual.
Lire plus01 août 2021
publication
Immune checkpoint inhibitors increase T cell immunity during SARS-CoV-2 infection.
Lire plus30 juil. 2021
28 juil. 2021
publication
SUMOylation of SAMHD1 at Lysine 595 is required for HIV-1 restriction in non-cycling cells.
Lire plus22 juil. 2021
news
SARS-CoV-2 : induces the dedifferentiation of multiciliated cells and impairs mucociliary clearance
Lire plus14 juil. 2021
publication
Analysis of T cell responses directed against the spike and/or membrane and/or nucleocapsid proteins in chilblain-like lesions patients during the COVID-19 pandemic.
Lire plus08 juil. 2021
02 juil. 2021
publication
Pregnancy complications and Interferon-induced transmembrane proteins (IFITM): balancing antiviral immunity and placental development.
Lire plus11 juin 2021
news
COVID-19: sensitivity of the Indian variant (B.1.617.2) to monoclonal antibodies and sera from convalescent and vaccinated individuals
Lire plus18 mai 2021
publication
Asymptomatic and symptomatic SARS-CoV-2 infections elicit polyfunctional antibodies.
Lire plus01 avr. 2021
publication
SARS-CoV-2 infection in schools in a northern French city: a retrospective serological cohort study in an area of high transmission, France, January to April 2020
Lire plus08 févr. 2021
publication
Rapid decline of neutralizing antibodies against SARS-CoV-2 among infected healthcare workers.
Lire plus01 févr. 2021
20 janv. 2021
01 janv. 2021
01 déc. 2020
20 oct. 2020
09 sept. 2020
02 sept. 2020
publication
A comparison of four serological assays for detecting anti–SARS-CoV-2 antibodies in human serum samples from different populations
Lire plus01 sept. 2020
publication
Serologic responses to SARS-CoV-2 infection among hospital staff with mild disease in eastern France.
Lire plus01 juin 2020
publication
Efficacy of Ultrasound for Localized Fat Treatment on Clinical and Psychological Outcomes: A Randomized, Single-Blind, Placebo-Controlled Clinical Trial.
Lire plus18 mai 2020
publication
Remodeling of the Core Leads HIV-1 Preintegration Complex into the Nucleus of Human Lymphocytes.
Lire plus05 févr. 2020
publication
Anti-HIV-1 antibodies trigger non-lytic complement deposition on infected cells.
Lire plus30 janv. 2020
publication
Structure of the prefusion-locking broadly neutralizing antibody RVC20 bound to the rabies virus glycoprotein.
Lire plus06 déc. 2019
publication
X-ray Structures of the Post-fusion 6-Helix Bundle of the Human Syncytins and their Functional Implications.
Lire plus15 oct. 2019
18 sept. 2019
publication
Atlastin Endoplasmic Reticulum-Shaping Proteins Facilitate Zika Virus Replication.
Lire plus12 juil. 2019
publication
IFITM proteins inhibit placental syncytiotrophoblast formation and promote fetal demise.
Lire plus20 juin 2019
publication
Proliferative memory SAMHD1low CD4+ T cells harbour high levels of HIV-1 with compartmentalized viral populations
Lire plus12 juin 2019
01 juin 2019
publication
Accelerated thymopoiesis and improved T-cell responses in HLA-A2/-DR2 transgenic BRGS-based human immune system mice.
Lire plus09 avr. 2019
publication
HIV-1 Envelope Recognition by Polyreactive and Cross-Reactive Intestinal B Cells
Lire plus08 avr. 2019
event
Groupe de Reflexion SIDA (GRS) seminar: “Determinants of HIV-1 broadly neutralizing antibody induction”
Lire plus04 avr. 2019
event
Department of Immunology seminar: Andrew Oberst, Too important to die: New antiviral roles for “cell death” pathways in the brain
Lire plus20 févr. 2019
18 sept. 2018
event
Groupe de Réflexion SIDA (GRS) seminar: “Defining Correlates of Immunology using Systems Serology”
Lire plus01 sept. 2018
01 août 2018
28 juil. 2018
29 mai 2018
publication
Conformational Plasticity in Broadly Neutralizing HIV-1 Antibodies Triggers Polyreactivity
Lire plus20 avr. 2018
event
“Functional CURE under some ENIGMATIC mechanisms: Choke-and-Mute, rather than Shoot-and-Kill ?” by Jacques Leibowitch – VIROLOGY DEPARTMENT SEMINAR
Lire plus17 avr. 2018
event
“Disruptive Discoveries for HIV, HCV and HBV Infections” by Raymond Schinazi – Virology & Immunology departments joint seminar
Lire plus21 nov. 2017
publication
More than meets the I: the diverse antiviral and cellular functions of interferon-induced transmembrane proteins
Lire plus13 oct. 2017
publication
HIV Fusion in Dendritic Cells Occurs Mainly at the Surface and Is Limited by Low CD4 Levels
Lire plus23 août 2017
10 juil. 2017
publication
HEXIM1 and NEAT1 Long Non-coding RNA Form a Multi-subunit Complex that Regulates DNA-Mediated Innate Immune Response
Lire plus14 juin 2017
publication
Zika virus induces massive cytoplasmic vacuolization and paraptosis-like death in infected cells.
Lire plus12 juin 2017
15 mars 2017
publication
CD32a is a marker of a CD4 T-cell HIV reservoir harbouring replication-competent proviruses
Lire plus15 mars 2017
publication
Ultrasensitive HIV-1 p24 Assay Detects Single Infected Cells and Differences in Reservoir Induction by Latency Reversal Agents.
Lire plus09 févr. 2017
publication
Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement
Lire plus02 févr. 2017
25 janv. 2017
11 janv. 2017
publication
SUN2 silencing impairs CD4 T cell proliferation and alters sensitivity to HIV-1 infection independently of Cyclophilin A
Lire plus10 janv. 2017
publication
Axl Mediates ZIKA Virus Entry in Human Glial Cells and Modulates Innate Immune Responses.
Lire plus10 oct. 2016
publication
CD4-mimetic sulfopeptide conjugates display sub-nanomolar anti-HIV-1 activity and protect macaques against a SHIV162P3 vaginal challenge
Lire plus12 sept. 2016
06 sept. 2016
publication
Natural mutations in IFITM3 modulate post-translational regulation and toggle antiviral specificity
Lire plus30 août 2016
12 juil. 2016
10 juin 2016
publication
HIV-Infected Dendritic Cells Present Endogenous MHC Class II-Restricted Antigens to HIV-Specific CD4+ T Cells
Lire plus12 mai 2016
03 mars 2016
03 mars 2016
01 mars 2016
12 févr. 2016
10 févr. 2016
05 févr. 2016
30 oct. 2015
publication
Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women
Lire plus14 oct. 2015
publication
The phosphatidylserine and phosphatidylethanolamine receptor CD300a binds dengue virus and enhances infection
Lire plus23 sept. 2015
14 sept. 2015
09 sept. 2015
project
REEMFOAMY : Human infection with zoonotic simian foamy retroviruses: role of virological and immunological factors in restricting viral emergence
Lire plus28 août 2015
publication
Inhibition of mTORC1 Enhances the Translation of Chikungunya Proteins via the Activation of the MnK/eIF4E Pathway
Lire plus25 août 2015
publication
Human Immunodeficiency Virus-1 Cell-To-Cell Transmission And Antiviral Strategies: An Overview
Lire plus05 août 2015
06 juil. 2015
01 juil. 2015
01 juil. 2015
publication
Plasmacytoid Dendritic Cell Infection and Sensing Capacity during Pathogenic and Nonpathogenic Simian Immunodeficiency Virus Infection.
Lire plus11 mai 2015
13 mars 2015
publication
Low SAMHD1 expression following T-cell activation and proliferation renders CD4+ T cells susceptible to HIV-1
Lire plus03 mars 2015
publication
Viral entry route determines how human plasmacytoid dendritic cells produce type I interferons
Lire plus27 janv. 2015
publication
Nef promotes evasion of human immunodeficiency virus type 1-infected cells from the CTLA-4-mediated inhibition of T-cell activation
Lire plus13 janv. 2015
26 nov. 2014
12 nov. 2014
publication
Distinct characteristics of endometrial and decidual macrophages and regulation of their permissivity to HIV-1 infection by SAMHD1.
Lire plus13 juin 2014
28 mars 2014
publication
Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes.
Lire plus20 févr. 2014
publication
Plasmacytoid dendritic cells engagement by influenza vaccine as a surrogate strategy for driving T-helper type 1 responses in human neonatal settings
Lire plus25 nov. 2013
31 oct. 2013
publication
Identification of novel compounds inhibiting chikungunya virus-induced cell death by high throughput screening of a kinase inhibitor library
Lire plus18 oct. 2013
05 sept. 2013
publication
Real-time whole-body visualization of Chikungunya Virus infection and host interferon response in zebrafish.
Lire plus20 août 2013
30 juil. 2013
publication
HIV-1 Nef promotes the localization of Gag to the cell membrane and facilitates viral cell-to-cell transfer
Lire plus10 janv. 2013
publication
Neonatal plasmacytoid dendritic cells (pDCs) display subset variation but can elicit potent anti-viral innate responses
Lire plus26 déc. 2012
publication
SAMHD1 restricts HIV-1 cell-to-cell transmission and limits immune detection in monocyte-derived dendritic cells
Lire plus12 oct. 2012
publication
Subcapsular sinus macrophages promote NK cell accumulation and activation in response to lymph-borne viral particles
Lire plus28 août 2012
27 juil. 2012
publication
Chikungunya-induced cell death is limited by ER and oxidative stress-induced autophagy
Lire plus12 juil. 2012
15 mai 2012
publication
Transcytosis of HTLV-1 across a tight human epithelial barrier and infection of subepithelial dendritic cells
Lire plus17 avr. 2012
16 avr. 2012
27 févr. 2012
publication
Cutting edge: independent roles for IRF-3 and IRF-7 in hematopoietic and nonhematopoietic cells during host response to Chikungunya infection
Lire plus16 nov. 2011
12 août 2011
publication
Automated genome-wide visual profiling of cellular proteins involved in HIV infection
Lire plus09 mars 2011
publication
A new role for the HTLV-1 p8 protein: increasing intercellular conduits and viral cell-to-cell transmission
Lire plus17 févr. 2011
12 août 2010
01 juil. 2010
17 juin 2010
10 mars 2010
publication
Preclinical studies of a modified vaccinia virus Ankara-based HIV candidate vaccine: antigen presentation and antiviral effect
Lire plus15 févr. 2010
publication
Type I IFN controls chikungunya virus via its action on nonhematopoietic cells.
Lire plus28 déc. 2009
publication
The antiviral factor APOBEC3G improves CTL recognition of cultured HIV-infected T cells
Lire plus12 août 2009
publication
Partial inhibition of human immunodeficiency virus replication by type I interferons: impact of cell-to-cell viral transfer
Lire plus15 avr. 2009
publication
Simultaneous cell-to-cell transmission of human immunodeficiency virus to multiple targets through polysynapses
Lire plus05 avr. 2009
publication
Live attenuated measles vaccine expressing HIV-1 Gag virus like particles covered with gp160DeltaV1V2 is strongly immunogenic
Lire plus12 déc. 2007
publication
Pediatric measles vaccine expressing a dengue antigen induces durable serotype-specific neutralizing antibodies to dengue virus
Lire plus13 juin 2007
01 juin 2007
24 mars 2007
01 nov. 2006
01 mai 2006
publication
Human immunodeficiency virus type-1 infection impairs the formation of the immunological synapse
Lire plus01 mai 2006
publication
DC-SIGN facilitates fusion of dendritic cells with human T-cell leukemia virus type 1-infected cells
Lire plus01 janv. 2006
15 nov. 2005
publication
DC-SIGN induction in alveolar macrophages defines privileged target host cells for mycobacteria in patients with tuberculosis
Lire plus01 sept. 2005
publication
Extensive editing of a small fraction of human T-cell leukemia virus type 1 genomes by four APOBEC3 cytidine deaminases
Lire plus01 mai 2005
publication
Covert human immunodeficiency virus replication in dendritic cells and in DC-SIGN-expressing cells promotes long-term transmission to lymphocytes
Lire plus12 avr. 2004
publication
Identification of cryptic MHC I-restricted epitopes encoded by HIV-1 alternative reading frames
Lire plus01 mars 2004
01 janv. 2004
publication
DC-SIGN from African green monkeys is expressed in lymph nodes and mediates infection in trans of simian immunodeficiency virus SIVagm.
Lire plus23 oct. 2003
01 mai 2003
publication
Inhibition of human immunodeficiency virus type 1 Env-mediated fusion by DC-SIGN
Lire plus27 févr. 2003
publication
DC-SIGN and L-SIGN are high affinity binding receptors for hepatitis C virus glycoprotein E2
Lire plus01 janv. 2002
publication