I have been the manager of the Pasteur Proteomics facility since September 2013. I am responsible for the operations of the proteomics platform and the coordination of the different ongoing projects. I did my PhD research in the group of Dr. Bernard Monsarrat and Dr. Odile Schiltz at the Institute of Pharmacology and Structural Biology (IPBS, University Paul Sabatier, UPS, also known as Toulouse III, France). As part of my PhD work, I used high-resolution mass spectrometers, including the LTQ-Orbitrap, in combination with various quantitative proteomic approaches. My focus was on stable isotope labelling strategies (SILAC and ICAT) to study the proteasome inhibitor effect in acute myeloid leukaemia cells. I then moved to the Institute of Molecular Systems Biology in Eidgenössische Technische Hochschule (ETH Zürich) as a post-doctoral fellow in the group of Professor Ruedi Aebersold. I worked on multiple projects using mass spectrometry to assess changes in protein abundance and posttranslational modifications, e.g., ubiquitin, SUMO, and chlorination of proteins using discovery-driven and targeted mass spectrometry. During this time, I utilised the new data independent acquisition mode developed in Ruedi Aebersold Lab, namely SWATH-MS.
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2022RNase E and HupB dynamics foster mycobacterial cell homeostasis and fitness., iScience 2022 May; 25(5): 104233.
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2022Experimental evolution links post-transcriptional regulation to Leishmania fitness gain., PLoS Pathog 2022 Mar; 18(3): e1010375.
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2021Listeriolysin S: A bacteriocin from Listeria monocytogenes that induces membrane permeabilization in a contact-dependent manner., Proc Natl Acad Sci U S A 2021 10; 118(40): .
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2021Cryptococcus extracellular vesicles properties and their use as vaccine platforms., J Extracell Vesicles 2021 Aug; 10(10): e12129.
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2021Quality standards in proteomics research facilities: Common standards and quality procedures are essential for proteomics facilities and their users., EMBO Rep 2021 May; (): e52626.
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2021Ser/Thr Kinase-Dependent Phosphorylation of the Peptidoglycan Hydrolase CwlA Controls Its Export and Modulates Cell Division in Clostridioides difficile., mBio 2021 May; 12(3): .
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2021RNase R is associated in a functional complex with the RhpA DEAD-box RNA helicase in Helicobacter pylori., Nucleic Acids Res 2021 49:5249-5264.
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2021Proteomic Analysis Uncovers Measles Virus Protein C Interaction with p65/iASPP Protein Complex., Mol Cell Proteomics 2021 Jan; (): 100049.
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2021Molecular basis of the interaction of the human tyrosine phosphatase PTPN3 with the hepatitis B virus core protein., Sci Rep 2021 Jan; 11(1): 944.
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2021CYP450 core involvement in multiple resistance strains of Aedes aegypti from French Guiana highlighted by proteomics, molecular and biochemical studies., PLoS One 2021 ; 16(1): e0243992.
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