I have been the manager of the Pasteur Proteomics facility since September 2013. I am responsible for the operations of the proteomics platform and the coordination of the different ongoing projects. I did my PhD research in the group of Dr. Bernard Monsarrat and Dr. Odile Schiltz at the Institute of Pharmacology and Structural Biology (IPBS, University Paul Sabatier, UPS, also known as Toulouse III, France). As part of my PhD work, I used high-resolution mass spectrometers, including the LTQ-Orbitrap, in combination with various quantitative proteomic approaches. My focus was on stable isotope labelling strategies (SILAC and ICAT) to study the proteasome inhibitor effect in acute myeloid leukaemia cells. I then moved to the Institute of Molecular Systems Biology in Eidgenössische Technische Hochschule (ETH Zürich) as a post-doctoral fellow in the group of Professor Ruedi Aebersold. I worked on multiple projects using mass spectrometry to assess changes in protein abundance and posttranslational modifications, e.g., ubiquitin, SUMO, and chlorination of proteins using discovery-driven and targeted mass spectrometry. During this time, I utilised the new data independent acquisition mode developed in Ruedi Aebersold Lab, namely SWATH-MS.
Click to view graph
Connections
Click to view timeline
Timeline
Projects
Software
Tools
Publications
Download-
2021Quality standards in proteomics research facilities: Common standards and quality procedures are essential for proteomics facilities and their users., EMBO Rep 2021 May; (): e52626.
-
2021Ser/Thr Kinase-Dependent Phosphorylation of the Peptidoglycan Hydrolase CwlA Controls Its Export and Modulates Cell Division in Clostridioides difficile., mBio 2021 May; 12(3): .
-
2021RNase R is associated in a functional complex with the RhpA DEAD-box RNA helicase in Helicobacter pylori., Nucleic Acids Res 2021 Apr; (): .
-
2021Proteomic Analysis Uncovers Measles Virus Protein C Interaction with p65/iASPP Protein Complex., Mol Cell Proteomics 2021 Jan; (): 100049.
-
2021Molecular basis of the interaction of the human tyrosine phosphatase PTPN3 with the hepatitis B virus core protein., Sci Rep 2021 Jan; 11(1): 944.
-
2021CYP450 core involvement in multiple resistance strains of Aedes aegypti from French Guiana highlighted by proteomics, molecular and biochemical studies., PLoS One 2021 ; 16(1): e0243992.
-
2021Proteomic Analysis of Humoral Immune Components in Bronchoalveolar Lavage of Patients Infected or Colonized by Aspergillus fumigatus., Front Immunol 2021 ; 12(): 677798.
-
2020Mass-spectrometry analysis of the human pineal proteome during night and day and in autism., J Pineal Res 2020 Dec; (): e12713.
-
2020ProteoCombiner: integrating bottom-up with top-down proteomics data for improved proteoform assessment., Bioinformatics 2020 Nov; (): .
-
2020Phosphorylation-Dependent Assembly of a 14-3-3 Mediated Signaling Complex during Red Blood Cell Invasion by Plasmodium falciparum Merozoites., mBio 2020 08; 11(4): .
-
+View full list of publications