I have been the manager of the Pasteur Proteomics facility since September 2013. I am responsible for the operations of the proteomics platform and the coordination of the different ongoing projects. I did my PhD research in the group of Dr. Bernard Monsarrat and Dr. Odile Schiltz at the Institute of Pharmacology and Structural Biology (IPBS, University Paul Sabatier, UPS, also known as Toulouse III, France). As part of my PhD work, I used high-resolution mass spectrometers, including the LTQ-Orbitrap, in combination with various quantitative proteomic approaches. My focus was on stable isotope labelling strategies (SILAC and ICAT) to study the proteasome inhibitor effect in acute myeloid leukaemia cells. I then moved to the Institute of Molecular Systems Biology in Eidgenössische Technische Hochschule (ETH Zürich) as a post-doctoral fellow in the group of Professor Ruedi Aebersold. I worked on multiple projects using mass spectrometry to assess changes in protein abundance and posttranslational modifications, e.g., ubiquitin, SUMO, and chlorination of proteins using discovery-driven and targeted mass spectrometry. During this time, I utilised the new data independent acquisition mode developed in Ruedi Aebersold Lab, namely SWATH-MS.
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2022Mitochondrial Fission Process 1 controls inner membrane integrity and protects against heart failure., Nat Commun 2022 Nov; 13(1): 6634.
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2022Bacterial Membrane Vesicles as a Novel Strategy for Extrusion of Antimicrobial Bismuth Drug in Helicobacter pylori., mBio 2022 Oct; 13(5): e0163322.
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2022In-depth characterization of the Clostridioides difficile phosphoproteome to identify Ser/Thr kinase substrates., Mol Cell Proteomics 2022 Oct; (): 100428.
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2022In-depth characterization of the Clostridioides difficile phosphoproteome to identify Ser/Thr kinase substrates, Mol Cell Proteomics .
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2022Analysis of the Human Pineal Proteome by Mass Spectrometry, Methods Mol Biol .
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2022Amphiregulin mediates non-cell-autonomous effect of senescence on reprogramming., Cell Rep 2022 Jul; 40(2): 111074.
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2022NAD kinase promotes Staphylococcus aureus pathogenesis by supporting production of virulence factors and protective enzymes., Elife 2022 Jun; 11(): .
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2022RNase E and HupB dynamics foster mycobacterial cell homeostasis and fitness., iScience 2022 May; 25(5): 104233.
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2022Experimental evolution links post-transcriptional regulation to Leishmania fitness gain., PLoS Pathog 2022 Mar; 18(3): e1010375.
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2021Listeriolysin S: A bacteriocin from Listeria monocytogenes that induces membrane permeabilization in a contact-dependent manner., Proc Natl Acad Sci U S A 2021 10; 118(40): .
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