I have been the manager of the Pasteur Proteomics facility since September 2013. I am responsible for the operations of the proteomics platform and the coordination of the different ongoing projects. I did my PhD research in the group of Dr. Bernard Monsarrat and Dr. Odile Schiltz at the Institute of Pharmacology and Structural Biology (IPBS, University Paul Sabatier, UPS, also known as Toulouse III, France). As part of my PhD work, I used high-resolution mass spectrometers, including the LTQ-Orbitrap, in combination with various quantitative proteomic approaches. My focus was on stable isotope labelling strategies (SILAC and ICAT) to study the proteasome inhibitor effect in acute myeloid leukaemia cells. I then moved to the Institute of Molecular Systems Biology in Eidgenössische Technische Hochschule (ETH Zürich) as a post-doctoral fellow in the group of Professor Ruedi Aebersold. I worked on multiple projects using mass spectrometry to assess changes in protein abundance and posttranslational modifications, e.g., ubiquitin, SUMO, and chlorination of proteins using discovery-driven and targeted mass spectrometry. During this time, I utilised the new data independent acquisition mode developed in Ruedi Aebersold Lab, namely SWATH-MS.
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2021Proteomic Analysis Uncovers Measles Virus Protein C Interaction with p65/iASPP Protein Complex., Mol Cell Proteomics 2021 Jan; (): 100049.
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2021Molecular basis of the interaction of the human tyrosine phosphatase PTPN3 with the hepatitis B virus core protein., Sci Rep 2021 Jan; 11(1): 944.
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2021CYP450 core involvement in multiple resistance strains of Aedes aegypti from French Guiana highlighted by proteomics, molecular and biochemical studies., PLoS One 2021 ; 16(1): e0243992.
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2020Mass-spectrometry analysis of the human pineal proteome during night and day and in autism., J Pineal Res 2020 Dec; (): e12713.
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2020ProteoCombiner: integrating bottom-up with top-down proteomics data for improved proteoform assessment., Bioinformatics 2020 Nov; (): .
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2020Phosphorylation-Dependent Assembly of a 14-3-3 Mediated Signaling Complex during Red Blood Cell Invasion by Plasmodium falciparum Merozoites., mBio 2020 08; 11(4): .
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2020Characterization of Extracellular Vesicles Produced by Aspergillus fumigatus Protoplasts., mSphere 2020 08; 5(4): .
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2020Shigella hijacks the exocyst to cluster macropinosomes for efficient vacuolar escape., PLoS Pathog 2020 08; 16(8): e1008822.
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2020Differentiation-dependent susceptibility of human muscle cells to Zika virus infection., PLoS Negl Trop Dis 2020 08; 14(8): e0008282.
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2020Insights into amebiasis using a human 3D-intestinal model., Cell Microbiol 2020 Aug; 22(8): e13203.
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