I have been the manager of the Pasteur Proteomics facility since September 2013. I am responsible for the operations of the proteomics platform and the coordination of the different ongoing projects. I did my PhD research in the group of Dr. Bernard Monsarrat and Dr. Odile Schiltz at the Institute of Pharmacology and Structural Biology (IPBS, University Paul Sabatier, UPS, also known as Toulouse III, France). As part of my PhD work, I used high-resolution mass spectrometers, including the LTQ-Orbitrap, in combination with various quantitative proteomic approaches. My focus was on stable isotope labelling strategies (SILAC and ICAT) to study the proteasome inhibitor effect in acute myeloid leukaemia cells. I then moved to the Institute of Molecular Systems Biology in Eidgenössische Technische Hochschule (ETH Zürich) as a post-doctoral fellow in the group of Professor Ruedi Aebersold. I worked on multiple projects using mass spectrometry to assess changes in protein abundance and posttranslational modifications, e.g., ubiquitin, SUMO, and chlorination of proteins using discovery-driven and targeted mass spectrometry. During this time, I utilised the new data independent acquisition mode developed in Ruedi Aebersold Lab, namely SWATH-MS.
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2020Insights into amebiasis using a human 3D-intestinal model, Cell. Microbiol. 2020 Mar;:e13203.
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2020Listeria monocytogenes Exploits Mitochondrial Contact Site and Cristae Organizing System Complex Subunit Mic10 To Promote Mitochondrial Fragmentation and Cellular Infection, mBio 2020 Feb;11(1).
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2020Class-A penicillin binding proteins do not contribute to cell shape but repair cell-wall defects, eLife 2020;9:e51998.
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2020Class-A penicillin binding proteins do not contribute to cell shape but repair cell-wall defects, Elife 2020 Jan;9.
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2019Dynamic Growth and Shrinkage of the Salmonella-Containing Vacuole Determines the Intracellular Pathogen Niche, Cell Rep 2019 Dec;29(12):3958-3973.e7.
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2019Assembly and disassembly of Aspergillus fumigatus conidial rodlets, The Cell Surface.
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2019Cell-wall synthases contribute to bacterial cell-envelope integrity by actively repairing defects, bioRxiv.
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2019Cryptococcus neoformans resists to drastic conditions by switching to viable but non-culturable cell phenotype, PLoS Pathog. 2019 Jul;15(7):e1007945.
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2019The Ser/Thr Kinase PrkC Participates in Cell Wall Homeostasis and Antimicrobial Resistance in Clostridium difficile, Infect. Immun. 2019 08;87(8).
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2019Post-translational acylation controls the folding and functions of the CyaA RTX toxin, FASEB J. 2019 Jun;:fj201802442RR.
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