© Thierry Blisnick & Philippe Bastin, Institut Pasteur
Bloodstream Trypanosoma brucei cell
Laboratory

Trypanosome Cell Biology

About

Welcome to the web site of the Trypanosome Cell Biology Unit (TRYPA)!

Our lab is studying the role and the functioning of the trypanosome flagellum, with perspectives in the field of both parasitology and genetic diseases.

Indeed, trypanosomes are significant parasites of man and cattle in central Africa and there are currently no efficient vaccines against them. Moreover, trypanosomes are also an excellent model to study human genetic diseases due to defects in cilia and flagella.

Our lab is a Pasteur full research unit and is affiliated to the Department of Parasites and Insect Vectors (headed by Ken Vernick) but also to the Department of Cell Biology and Infection (headed by Chiara Zurzolo). We also belong to a larger INSERM unit (U1201, headed by Artur Scherf) that involves two other teams working on Plasmodium and on Leishmania. We are also part of the LabEx IBEID, a consortium coordinated by Professors Philippe Sansonetti and Pascale Cossart whose aim is to develop a structure to anticipate and tackle emerging infectious diseases (EIDs).

Finally, we are labelled as “équipe FRM” (Fondation pour la Recherche Médicale)

We live on the first floor of the Nicolle building but are travelling regularly through the multiple platforms of the campus.

 

LATEST NEWS:

 

22th July. The whole lab participated to “Roulez solidaires” where we cycled to raise funding for the Institut Pasteur.

Group_cycling

 

29th June. Sadly Keith Vickerman died last night. Keith was a precursor in protist biology and the first one to link morphogical and molecular biology studies. He gave an inspiring talk in Pasteur in the Trypanosome Flagellum Meeting in 2006 (photo below).

Vickerman

26th June. Cécile’s paper demonstrating the role of IFT in flagellum maintenance is published. Click here for connexion to the publisher site.

10-12th May. We had a vibrant lab retreat in La Rochelle, where everybody gave a talk leading to stimulating discussions and plenty of new ideas!

Trypa_LaRochelle_01_small

OTHER NEWS: see bottom of the page

VIDEO: Click here for a general presentation of sleeping sickness (in French)

 

 

Projects

Fundings

  • Agence_Nationale_de_la_Recherche
  • original
  • logo_frm_blanc_gros
  • logo_gdr
  • inserm_1
  • label-ia_0

Publications

TRYPA news

Dernières nouvelles

10 mars. Félicitations à Brice qui a défendu avec succès son HDR aujourd’hui !

29 Janvier. Petite fête au labo à l’occasion du dernier jour de Sylvie. Elle va nous manquer (et probablement aussi aux mouches).Cropped_IMG_8288

1 février. Arrivée de Moara Lemos qui va étudier comment les moteurs interagissent avec les microtubules et les complexes IFT.

29 janvier. Départ de Sylvie qui déménage en Bourgogne pour raisons familiales après plus de 30 ans de bons et loyaux services !

14th October: Félicitations à Eloïse qui a remporté un des deux prix pour la meilleure présentation orale au 9th Cilia, Flagella and Centrosomes meeting à Strasbourg !

9th October: Nous combattons les virus au Pasteurdon! Grâce à la générosité des donateurs,  1.2 Mo € de promesses de dons ont été faites en faveur de l’Institut Pasteur.

Capture d’écran 2015-10-09 à 22.40.22 Capture d’écran 2015-10-09 à 22.42.34

1st October: Bienvenue à Jamin Jung qui démarre son postdoc avec nous pour étudier le rôle d’ IFT172 en collaboration avec l’équipe d’Esben Lorentzen au MPI.

Contact

Phone:
Email:

Address
25-28 Rue du Docteur Roux
75015, Paris
France