© Thierry Blisnick & Philippe Bastin, Institut Pasteur
Bloodstream Trypanosoma brucei cell

Trypanosome Cell Biology


Welcome to the web site of the Trypanosome Cell Biology Unit (TRYPA)!

Our lab is studying the role and the functioning of the trypanosome flagellum, with perspectives in the field of both parasitology and genetic diseases.

Indeed, trypanosomes are significant parasites of man and cattle in central Africa and there are currently no efficient vaccines against them. Moreover, trypanosomes are also an excellent model to study human genetic diseases due to defects in cilia and flagella.

Our lab is a Pasteur full research unit and is affiliated to the Department of Parasites and Insect Vectors (headed by Ken Vernick) but also to the Department of Cell Biology and Infection (headed by Chiara Zurzolo). We also belong to a larger INSERM unit (U1201, headed by Artur Scherf) that involves two other teams working on Plasmodium and on Leishmania. We are also part of the LabEx IBEID, a consortium coordinated by Professors Philippe Sansonetti and Pascale Cossart whose aim is to develop a structure to anticipate and tackle emerging infectious diseases (EIDs).

Finally, we are labelled as “équipe FRM” (Fondation pour la Recherche Médicale)

We live on the first floor of the Nicolle building but are travelling regularly through the multiple platforms of the campus.


LATEST NEWS: 10-12th May. We had a vibrant lab retreat in La Rochelle, where everybody gave a talk leading to stimulating discussions and plenty of new ideas!


OTHER NEWS: see bottom of the page

VIDEO: Click here for a general presentation of sleeping sickness (in French)





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TRYPA news

10th March. Congratulations to Brice who successfully obtained his “habilitation à diriger des recherches” (HDR) today.

29th January. We had a small party in the lab to celebrate Sylvie‘s last day. We (and probably the flies too!) will miss her.Cropped_IMG_8288

1st February 2016: Arrival of Moara Lemos as a FRM postdoctoral fellow. She is going to investigate how kinesin and dynein motors interact with IFT trains and microtubules.

25th January 2016: Visit of Sebastian Hutchinson (Dundee) who gave a talk on the control of VSG gene expression

19th January 2016:  Arrival of Aline Crouzols who is going to replace Sylvie for breeding and infection of tsetse flies. Sylvie is moving to Burgundy for family reasons and will leave Institut Pasteur after more than 30 years of exceptional service!

14th October 2015: Congratulations to Eloïse who won an award for best oral presentation at the 9th Cilia, Flagella and Centrosomes meeting in Strasbourg today!

1st October 2015: Welcome to Jamin Jung who is starting his postdoc with us working on the role of IFT172 in collaboration with the group of Esben Lorentzen at the MPI.

9th October 2015: Fighting viruses for the Pasteurdon! Thanks to the generosity of donators, more than 1.2 Mo € were raised for the Institut Pasteur.

Capture d’écran 2015-10-09 à 22.40.22Capture d’écran 2015-10-09 à 22.42.34


Phone: +33 1 45 68 86 27
Email: anne.cozanet@pasteur.fr

25-28 Rue du Docteur Roux
75015, Paris