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© Thierry Blisnick & Philippe Bastin, Institut Pasteur
Bloodstream Trypanosoma brucei cell
Scientific Fields
Diseases
Organisms
Applications
Technique

About

Aline obtained her PhD degree at Federal University of Rio de Janeiro (Brazil) in 2019. She worked on characterising expression and function of myosin motors in Trypanosoma cruzi under supervision of Dr. Narcisa Cunha-e-Silva. She had a sandwich period at Keith Gull’s lab (University of Oxford) and Sue Vaughan’s lab (Oxford Brookes University) in England, where she identified two new cytosolic assembly factors of paraflagellar rod in Trypanosoma brucei under supervision of Dr. Jack Sunter.
Aline joined the group as a post-doctoral researcher at February 2020 to describe the role of kinesin motors on reading tubulin glutamylation code and how this code can drive the movement of IFT trains along the axoneme of Trypanosoma brucei flagellum.

Projects

Project
Not started
5 Members

Deciphering how cells write and read the tubulin code

Philippe Bastin (PI)

Microtubules are cytoskeletal elements that are central to cell life. Their primary components are tubulins and undergo various post-translational modifications acting as a tubulin code. Here, we wish to investigate a main modification called […]
Project
Ongoing
12 Members

Role of tubulin glutamylation in flagellum construction (TUBGLUFLA)

Philippe Bastin (PI)

Cilia and flagella are essential eukaryotic organelles composed of an evolutionary conserved structure of 9 doublet microtubules that are similar but not equivalent. We propose that a tubulin post-translational modification called glutamylation could act […]