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© Thierry Blisnick & Philippe Bastin, Institut Pasteur
Bloodstream Trypanosoma brucei cell
Scientific Fields
Diseases
Organisms
Applications
Technique

About

Daniel obtained his Master’s degree in the lab of Isabel Roditi at the University of Bern (Switzerland). There he investigated the role of proteins associated with cyclic AMP signaling in an in vitro assay termed social motility.
Daniel joined the group to start his PhD in October 2020. His project addresses several questions on how different components (e.g. tubulin) are incorporated during the construction of new flagella, as well as mechanisms on how further assembly is locked in the mature ones. Furthermore, he will investigate how African trypanosomes assemble flagella of different length when progressing through the different stages of the life cycle.

Projects

Project
Ongoing
5 Members

Functional Analysis of novel centrosomal and basal body components of two human parasitic protozoa

Philippe Bastin (PI)

Centrosomes (Cs) are the main microtubule organizing centers of many eukaryotic cells with critical roles in cell division, polarity, signaling and structure. Centrioles can act as basal bodies (BB), nucleating microtubules to form cilia […]
Project
Not started
5 Members

Deciphering how cells write and read the tubulin code

Philippe Bastin (PI)

Microtubules are cytoskeletal elements that are central to cell life. Their primary components are tubulins and undergo various post-translational modifications acting as a tubulin code. Here, we wish to investigate a main modification called […]