Innate Immunity

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Administrative Staff
Assistant Professor
Associate Professor
Clinical Research Assistant
Full Professor
Graduate Student
Lab assistant
Non-permanent Researcher
Permanent Researcher
Pharmacist
PhD Student
Physician
Post-doc
Project Manager
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Retired scientist
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Undergraduate Student
Veterinary
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Appointments

Deputy Director of Center
Deputy Director of Department
Deputy Director of National Reference Center
Deputy Head of Facility
Director of Center
Director of Department
Director of Institute
Director of National Reference Center
Group Leader
Head of Facility
Head of Operations
Head of Structure
Honorary President of the Departement
Labex Coordinator

Content 2

Content Type

member
team
department
center
program_project
nrc
whocc
project
software
tool
patent

Keywords

Positions

Administrative Staff
Assistant Professor
Associate Professor
Clinical Research Assistant
Full Professor
Graduate Student
Lab assistant
Non-permanent Researcher
Permanent Researcher
Pharmacist
PhD Student
Physician
Post-doc
Project Manager
Research Associate
Research Engineer
Retired scientist
Technician
Undergraduate Student
Veterinary
Visiting Scientist

Appointments

Deputy Director of Center
Deputy Director of Department
Deputy Director of National Reference Center
Deputy Head of Facility
Director of Center
Director of Department
Director of Institute
Director of National Reference Center
Group Leader
Head of Facility
Head of Operations
Head of Structure
Honorary President of the Departement
Labex Coordinator

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Stem Cells And Development

Experimental neuropathology

Scientific Fields

Diseases

Organisms

Applications

Technique

Scientific Fields

Diseases

Organisms & Organs

Model systems
Mouse

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About

The Innate Immunity Unit comprises 18 members (4 permanent scientists, 4 engineers/technicians, 5 postdoctoral fellows, 5 PhD students) with complementary interests and expertise in immunology, developmental biology, virology and animal models.

Together with the Lymphopoiesis Unit (Ana Cumano), Dynamics of Immune Response Unit (Philippe Bousso) and Immunobiology of Dendritic Cells Unit (Stanislas Pol), we form the Inserm Unit 1223 (Pathophysiology of the Immune System) that pursues collaborative projects involving lymphocyte development, differentiation and functional dynamics in mouse and man.

Members

James Di Santo

Head of Structure

Head

Hélène Strick-Marchand

Group Leader

Christian Vosshenrich

Guillemette Masse-Ranson

Innate lymphoid cells (ILC) are a newly described family of hematopoietic cells that lack antigen-specific receptors but can be activated to promptly produce large amounts of cytokines (including interleukin (IL)-5, -13, -17A, -22, TNF-α […]

project

Ongoing

6 Members

Think tank: Mucosal Immunology

Gérard Eberl (PI)

The Think tank Mucosal Immunology gathers several research units form the departments of immunology, microbiology, cellular biology and epidemilogy and infection, as well as from the Institut Imagine (Necker) and Hôpital Paul Brousse. It […]

project

Ongoing

8 Members

Mouse Model to Understand Innate Lymphoid Cell Biology

James Di Santo (PI)

Mucosal homeostasis requires a delicate equilibrium between immune mechanisms and commensal microorganisms that impacts on the development and maintenance of critical physiological processes including digestion, metabolism or host defense. Several infectious or inflammatory disorders […]

project

Ongoing

3 Members

Pathogen co-infection : HIV, TB, Malaria and HCV

James Di Santo (PI)

Acquired immune deficiency syndrome (AIDS), tuberculosis (TB) and malaria are the primary infectious diseases causing death world wide. TB is responsible for a third to a half of human immunodeficiency virus type 1 (HIV-1)–associated […]

project

Ongoing

5 Members

Host responses to microbial intestinal invasion, impact on microbial dissemination

Marc Lecuit (PI)

We study the impact of the portal of entry of microbes in the intestine on host responses and microbial dissemination. To this end, we combine in vivo, ex vivo and in vitro systems, as well […]

project

ongoing

1 Member

A novel mouse model for conditional gene targeting

James Di Santo (PI)

Research in the Innate Immunity Unit strives to understand the signals that regulate lymphoid lineage development and the mechanisms that promote the functional diversification of lymphocyte responses. Modeling Hepatitis B virus infections in a […]

Transversal Project

INCEPTION – Institut Convergence for the study of Emergence of Pathology Through Individuals and Populations

IINCEPTION Goal The Inception’s goal is to develop a core structure to mobilize data resources, numerical sciences, and fundamental experimental biology in a range of health issues. Inception program uses Integrative Biology, Social Science […]

The Healthy Human Global Project

Susceptibility to infections, disease progression and severity, and response to medical therapies and vaccines are highly variable from one individual to another. The complexity of individual immune responses is such that it has not […]

LabEx Milieu Intérieur

The Milieu Intérieur project provides insight into the core of human diversity by dissecting the interplay between genetics and environment and their impact on the immune system. The Milieu Intérieur Project While the immune […]

LabEx Revive – Regenerative biology & medicine

Rationale and Objectives of Revive Consortium Major advancements in stem cell biology have paved the way for concerted research activities on the fundamental biology of stem cells and their applications in the clinic. […]