Darragh Duffy leads the Translational Immunology unit at the Institut Pasteur, Paris and is co-coordinator of the LabEx Milieu Interieur project. The overall goal of his research is to better understand the fundamental mechanisms behind inter-individual differences in immune responses, and apply these discoveries to relevant clinical questions. To do this they use cellular mechanistic models, population immunology cohorts, and experimental clinical studies in infection and autoimmunity. They work closely with clinical collaborators with the goal that the research findings will help to develop new patient management strategies. For fundamental questions related to understanding immune variability they apply systems immunology approaches to diverse phenotypes and integrate with genetic and environmental factors.
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10th HKU-Pasteur Immunology Course: December 2-15, 2018
‘Quantitative Immunology’ will be the theme of the 10th anniversary of the HKU-Pasteur Immunology Course. We will explore the ongoing transition from reductionist studies, based on the application of genetic approaches in animal models, […]
2018-12-02 09:00:00
2018-12-15 18:00:00
Europe/Paris
10th HKU-Pasteur Immunology Course: December 2-15, 2018
‘Quantitative Immunology’ will be the theme of the 10th anniversary of the HKU-Pasteur Immunology Course. We will explore the ongoing transition from reductionist studies, based on the application of genetic approaches in animal models, […]
HKU-Pasteur Research Centre, Hong Kong
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2024Cytokine Autoantibodies Alter Gene Expression Profiles of Healthy Donors., Eur J Immunol 2024 Nov; (): e202451211.
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2024Increased mortality in diffuse systemic sclerosis patients with high circulating IFNα levels., J Invest Dermatol 2024 Nov; (): .
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2024From Gut to Blood: Redistribution of Zonulin in People Living with HIV., Biomedicines 2024 Oct; 12(10): .
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2024Scientific Business Abstracts., QJM 2024 Sep; (): .
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2024SARS-CoV-2 brainstem encephalitis in human inherited DBR1 deficiency., J Exp Med 2024 Sep; 221(9): .
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2024Immune system adaptation during gender-affirming testosterone treatment., Nature 2024 Sep; 633(8028): 155-164.
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2024Hereditary C1q Deficiency is Associated with Type 1 Interferon-Pathway Activation and a High Risk of Central Nervous System Inflammation., J Clin Immunol 2024 Aug; 44(8): 185.
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2024The brain microvasculature is a primary mediator of interferon-α neurotoxicity in human cerebral interferonopathies., Immunity 2024 Jul; 57(7): 1696-1709.e10.
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2024Increased levels of GM-CSF and CXCL10 and low CD8+ memory stem T Cell count are markers of immunosenescence and severe COVID-19 in older people., Immun Ageing 2024 May; 21(1): 28.
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2024Sarcoidosis immunopathogenesis – a new concept of maladaptive trained immunity, Trends Immunol. 2024 May 24:S1471-4906(24)00101-7.
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