Innate Immunity MOOC
This MOOC describes the players and the whole orchestra involved in innate immunity against pathogens. Register on : https://www.fun-mooc.fr/en/courses/innate-immunity/ Description: More than a century ago, Elie Metchnikoff established the bases of cellular innate immunity […]
MOOC Viruses and Human Cancers
The MOOC offers a broad overview of the state of knowledge on viruses associated with cancer, the different mechanisms of carcinogenesis, the host immune response and progress in preventing tumors. Registration on: https://www.fun-mooc.fr/en/courses/viruses-and-human-cancers/ […]
Projet de Recherche Clinique : Impact des mutations du gène APC (Adenomatous polyposis coli) dans les réponses immunes anti-tumorales
La polypose adénomateuse familiale est une maladie caractérisée par l’apparition dans l’intestin de nombreux polypes susceptibles d‘évoluer en cancer en l’absence de prise en charge. Il s’agit d’une maladie génétique rare, le plus souvent […]
ANRS-EP38-IMMIP : Immune status after long term HIV infection in the perinatal period
Perinatal HIV infection – ANRS-EP38-IMMIP Potent combined antiretroviral therapy has transformed HIV disease into a stable chronic condition. Infected children born at the beginning of the epidemic are now reaching adulthood. The unique characteristics […]
Etude ANRS-EP59-CLEAC (Comparison of Late versus Early Antiretroviral therapy in HIV-infected Children) : Etude physiopathologique comparant l’impact de l’instauration précoce (avant 6 mois) ou tardive (après 2 ans) du traitement antirétroviral sur l’évolution immuno-virologique des enfants infectés par le VIH-1 en période périnatale)
A collaborative study with members of Pasteur Institute (A. Saez-Cirion, D. Scott-Algara), french perinatal cohort (ANRS CO10; J. Warszawsky) and 10 hospitals from Paris Area (Principal investigator, P. Frange). The study has included 76 […]
Innate Immunity and HIV infection
Role of NK/DC interaction in the induction of specific immune responses to HIV antigens Jean-Saville Cummings, PhD Vincent Arnold Celine Didier Reciprocal activation of NK cells and DCs through NK/DC interactions is now […]
2015S100A9 Tetramers, Which are Ligands of CD85j, Increase the Ability of MVAHIV-Primed NK Cells to Control HIV Infection, Front Immunol 2015;6:478.
2014Phenotype alterations in regulatory T-cell subsets in primary HIV infection and identification of Tr1-like cells as the main interleukin 10-producing CD4+ T cells, J. Infect. Dis. 2015 Mar;211(5):769-79.
2014Natural killer cell responses to dendritic cells infected by the ANRS HIV-1 vaccine candidate, MVAHIV, Vaccine 2014 Sep;32(43):5577-84.
2014Reduction of death receptor 5 expression and apoptosis of CD4+ T cells from HIV controllers, Clin. Immunol. 2014 Nov;155(1):17-26.
2014NK cells are primed by ANRS MVA(HIV)-infected DCs, via a mechanism involving NKG2D and membrane-bound IL-15, to control HIV-1 infection in CD4+ T cells, Eur. J. Immunol. 2014 Aug;44(8):2370-9.
2014Naive T lymphocytes and recent thymic emigrants are associated with HIV-1 disease history in french adolescents and young adults infected in the perinatal period: the ANRS-EP38-IMMIP study, Clin. Infect. Dis. 2014 Feb;58(4):573-87.
2013TLR-mediated activation of NK cells and their role in bacterial/viral immune responses in mammals, Immunol. Cell Biol. 2014 Mar;92(3):256-62.
2013S100A9 protein is a novel ligand for the CD85j receptor and its interaction is implicated in the control of HIV-1 replication by NK cells, Retrovirology 2013;10:122.
2013The Th17/Treg ratio, IL-1RA and sCD14 levels in primary HIV infection predict the T-cell activation set point in the absence of systemic microbial translocation, PLoS Pathog. 2013;9(6):e1003453.
2013Molecular characterization of avian reovirus isolates in Tunisia, Virol. J. 2013;10:12.
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