In the Ghigo laboratory, my work focuses on two biofilm-specific phenomena: initial adhesion to surfaces or between bacteria, which is a key step of any colonization process, and biofilms recalcitrance towards antibiotics , a major biofilm behavior responsible for chronic and recurrent infections. Beyond the importance of a better fundamental understanding of the molecular mechanisms controlling these two biofilm-properties , these studies have also been motivated by my desire to translate, when possible, some aspects of my work into clinically relevant situations involving biofilms.
