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About

Microorganisms have dominated most of life history and represent the largest fraction of the biosphere. However, much of their diversity is still unknown, as are many aspects of their evolutionary history.

In our group we use cutting-edge phylogenomics approaches to study the macroevolutionary processes that led to the current diversity of microorganisms, with an original view on the whole Tree of Life. We are particularly interested in resolving the global phylogenies of both Bacteria and Archaea, reconstructing the evolutionary relationships among the three domains of Life, and highlighting the existence of novel and important microbial clades. These robust phylogenetic frames are essential to reconstruct the diversity and evolutionary history of key microbial cellular processes, with an important component of functional annotation and gene discovery, which drives experimental work. Together, our researches allow us to address major evolutionary transitions in the history of life, and to challenge established paradigms in ancient microbial evolution.

We have recently started new experimental axes to complement and test our evolutionary hypotheses. These focus on the biology of methanogens associated to the animal and human microbiome, and on the evolution of the archaeal and bacterial cell envelope. We have developed Methanobrevibacter smithii and Veillonella parvula as new archaeal and bacterial model organisms from the human microbiome.

Former Members

2000
2000
Name
Position
2005
2009
Diego Cortez
PhD Student
2006
2009
Elie Desmond
PhD Student
2008
2010
Alexis Criscuolo
Post-doc
2011
2013
Kasie Raymann
PhD Student
2013
2015
Luisa Antunes
Post-doc
2015
2020
Julie Perreau
Graduate Student
2014
2017
Daniel Poppleton
PhD Student
2015
2018
Panagiotis Adam
PhD Student
2018
2020
Zerrin Uzum
Post-doc
2017
2020
Daniela Megrian
PhD Student
2017
2021
Anna Spier
PhD Student
2018
2021
Fabrizia Stavru
Researcher
2018
2022
Thomas Courtney
PhD Student
2018
2022
Pende Nika
Post-doc
2018
2022
To Tham Nam
Research Engineer
2022
2022
Vorobev Alexey
Post-doc
2022
2022
Kathryn Appler
Visiting scientist
2023
2023
Joanna Klim
Visiting scientist
2021
2024
Sofia Medvedeva
Post-doc
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Courses

Introduction à la Phylogénie Moléculaire : Concepts, méthodes et interprétation

Ce cours a pour objectif d’enseigner les bases théoriques et pratiques nécessaires à la conduite d’analyses phylogénétiques. Les sessions théoriques seront consacrées aux bases du domaine (représentation et combinatoire des arbres, modèles d’évolution) et […]

2021-12-13 09:00:00 2021-12-17 19:00:00 Europe/Paris Introduction à la Phylogénie Moléculaire : Concepts, méthodes et interprétation Ce cours a pour objectif d’enseigner les bases théoriques et pratiques nécessaires à la conduite d’analyses phylogénétiques. Les sessions théoriques seront consacrées aux bases du domaine (représentation et combinatoire des arbres, modèles d’évolution) et […] 28 Rue du Dr Roux, Paris, France

Projects

Transversal Project

Fundings

Publications

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