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  • Master Student
  • MD-PhD Student
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  • PhD Student
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  • Undergraduate Student
  • Veterinary
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  • Director of Center
  • Director of Department
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About

Guillaume has been a post-doctoral researcher funded by a Roux fellowship of the Institut Pasteur (2015-2017).

Since January 2018 he has a permanent research position at the Institut Pasteur.

His project focuses on the diversity and evolution of archaeal methanogens and their adaptation to different environments, including the human digestive tract.

Projects

Project
Ongoing
7 Members

ANR-FirstFeS: In search of the ancestral machineries for Iron-Sulfur biogenesis

Frédéric Barras (PI)

Iron-sulfur (Fe-S) clusters are ancient and ubiquitous protein cofactors essential for life. It is thought that Fe-S clusters spontaneously assembled in the early Earth anaerobic environment rich in iron and sulfur. Rise of oxygen […]
Project
Ongoing
6 Members

Labex GIL: Methanobrevibacter and Veillonella crosstalk with the intestinal mucosa in the context of health and inflammation

Simonetta Gribaldo (PI)

Alterations of the gut microbiota are associated with numerous diseases, of which many involve impaired immune tolerance, such as allergies. However, the role of specific microorganisms and underlying molecular mechanisms remain poorly characterised. Archaeal […]
Project
Ongoing
9 Members

FRM- Human-associated archaea: evolution, adaptation, interactions

Simonetta Gribaldo (PI)

The Archaea are largely known as microorganisms thriving in extreme environments, but are in fact ubiquitouly found in nature. Importantly, archaeal methanogens are also stable members of the human gastrointestinal tract (GIT), where they […]
Project
Ongoing
3 Members

ANR-METHEVOL: Characterization of new players and evolutionary transitions in the methane metabolism, a backbone in the evolution of the archaeal domain

Guillaume Borrel (PI)

Methanogenesis is an archaeal-specific metabolism that could have been active as early as 3.5 Gy ago with a direct impact on the evolution of the Earth’s climate system, as well as on current global […]
Project
Ongoing
6 Members

ANR VIROMET: Uncovering the VIRome of archaeal METhanogens

Simonetta Gribaldo (PI)

Methanogenic archaea are phylogenetically diverse, ancient and environmentally widespread. They are common inhabitants of the gastrointestinal tract of humans and other animals, and produce methane, a potent green-house gas, as a metabolic by-product. Despite […]
Project
Completed
4 Members

ANR-Arch-Evol: Phylogenomic approaches to investigate the origin and evolution of the Archaea

Simonetta Gribaldo (PI)

The Archaea represent an understudied but important fraction of microbial diversity present in a wide variety of environments and ecosystems, including the human body. They have key ecological roles and a unique place in […]

Publications

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