-
2022Human peroxiredoxin 6 is essential for malaria parasites and provides a host-based drug target., Cell Rep 2022 Jun; 39(11): 110923.
-
2022Enabling reactive microscopy with MicroMator, Nat Commun 2022 Apr; 13(1): 2199.
-
2022Topoisomerase I (TOP1) dynamics: conformational transition from open to closed states., Nat Commun 2022 01; 13(1): 59.
-
2021Actinobacteria challenge the paradigm: A unique protein architecture for a well-known, central metabolic complex., Proc Natl Acad Sci U S A 2021 Nov; 118(48): .
-
2021A systematic review of Mycobacterium leprae DNA gyrase mutations and their impact on fluoroquinolone resistance., Clin Microbiol Infect 2021 Nov; 27(11): 1601-1612.
-
2021A Tetratricopeptide Repeat Scaffold Couples Signal Detection to OdhI Phosphorylation in Metabolic Control by the Protein Kinase PknG., mBio 2021 Oct; 12(5): e0171721.
-
2021Proteome remodeling in the Mycobacterium tuberculosis PknG knockout: Molecular evidence for the role of this kinase in cell envelope biogenesis and hypoxia response., J Proteomics 2021 07; 244(): 104276.
-
2021SepF is the FtsZ anchor in archaea, with features of an ancestral cell division system., Nat Commun 2021 06; 12(1): 3214.
-
2020Novel ribonucleotide discrimination in the RNA polymerase-like two-barrel catalytic core of Family D DNA polymerases., Nucleic Acids Res 2020 12; 48(21): 12204-12218.
-
2020Population genomics and antimicrobial resistance in Corynebacterium diphtheriae., Genome Med 2020 11; 12(1): 107.
-
2020Genome-wide analysis of the Firmicutes illuminates the diderm/monoderm transition., Nat Ecol Evol 2020 12; 4(12): 1661-1672.
-
2020Polymorphisms of IL-4 and IL-4R are associated to some demographic characteristics of differentiated thyroid cancer patients but are not determinants of risk in the Brazilian population., Endocrine 2020 Sep; (): .
-
2020Shedding X-ray Light on the Role of Magnesium in the Activity of Mycobacterium tuberculosis Salicylate Synthase (MbtI) for Drug Design., J Med Chem 2020 07; 63(13): 7066-7080.
-
2020Unraveling the role of thiosulfate sulfurtransferase in metabolic diseases., Biochim Biophys Acta Mol Basis Dis 2020 06; 1866(6): 165716.
-
2020Molecular Target Validation of Aspartate Transcarbamoylase from Plasmodium falciparum by Torin 2., ACS Infect Dis 2020 05; 6(5): 986-999.
-
2020Essential dynamic interdependence of FtsZ and SepF for Z-ring and septum formation in Corynebacterium glutamicum., Nat Commun 2020 Apr; 11(1): 1641.
-
2020One or two membranes? Diderm Firmicutes challenge the Gram-positive/Gram-negative divide., Mol Microbiol 2020 03; 113(3): 659-671.
-
2020A novel mechanism of inhibition by phenylthiourea on PvdP, a tyrosinase synthesizing pyoverdine of Pseudomonas aeruginosa., Int J Biol Macromol 2020 Mar; 146(): 212-221.
-
2020New directions in antimalarial target validation., Expert Opin Drug Discov 2020 02; 15(2): 189-202.
-
2020Unexpected electron spin density on the axial methionine ligand in Cu suggests its involvement in electron pathways, Chem. Commun. (Camb.) 2020 Jan;56(8):1223-1226.
-
2020Selective Inhibition of 2-Oxoglutarate and 2-Oxoadipate Dehydrogenases by the Phosphonate Analogs of Their 2-Oxo Acid Substrates., Front Chem 2020 ; 8(): 596187.
-
2019High-Throughput Crystallization Pipeline at the Crystallography Core Facility of the Institut Pasteur, Molecules 2019 Dec;24(24).
-
2019New insight into structure-activity of furan-based salicylate synthase (MbtI) inhibitors as potential antitubercular agents., J Enzyme Inhib Med Chem 2019 Dec; 34(1): 823-828.
-
2019Conformational transitions in the active site of mycobacterial 2-oxoglutarate dehydrogenase upon binding phosphonate analogues of 2-oxoglutarate: From a Michaelis-like complex to ThDP adducts., J Struct Biol 2019 11; 208(2): 182-190.
-
2019Host nutritional status affects alphavirus virulence, transmission, and evolution., PLoS Pathog 2019 11; 15(11): e1008089.
-
2019Chikungunya Virus Vaccine Candidates with Decreased Mutational Robustness Are Attenuated In Vivo and Have Compromised Transmissibility., J Virol 2019 09; 93(18): .
-
2019Arabidopsis thaliana Hcc1 is a Sco-like metallochaperone for Cu assembly in Cytochrome c Oxidase, FEBS J. 2020 Feb;287(4):749-762.
-
2019[Faced with predatory magazines, how can we stop being rabbits ?], Med Sci (Paris) 2019 Jun-Jul;35(6-7):562-564.
-
2019Novel mechanistic insights into physiological signaling pathways mediated by mycobacterial Ser/Thr protein kinases., Microbes Infect ; 21(5-6): 222-229.
-
2019Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling., Sci Signal 2019 05; 12(580): .
-
2019Novel mechanistic insights into physiological signaling pathways mediated by mycobacterial Ser/Thr protein kinases., Genes Immun 2019 05; 20(5): 383-393.
-
2019Double autoinhibition mechanism of signal transduction ATPases with numerous domains (STAND) with a tetratricopeptide repeat sensor, Nucleic Acids Res. 2019 Apr;47(7):3795-3810.
-
2019The crystal structure of Rv2991 from Mycobacterium tuberculosis: An F binding protein with unknown function, J. Struct. Biol. 2019 May;206(2):216-224.
-
2019New substrates and interactors of the mycobacterial Serine/Threonine protein kinase PknG identified by a tailored interactomic approach., J Proteomics 2019 02; 192(): 321-333.
-
2019Overall Structures of Mycobacterium tuberculosis DNA Gyrase Reveal the Role of a Corynebacteriales GyrB-Specific Insert in ATPase Activity, Structure 2019 04;27(4):579-589.e5.
-
2018The Reaction Mechanism of Metallo-β-Lactamases Is Tuned by the Conformation of an Active-Site Mobile Loop, Antimicrob. Agents Chemother. 2019 Jan;63(1).
-
2018The synthesis and kinetic evaluation of aryl α-aminophosphonates as novel inhibitors of T. cruzi trans-sialidase, Eur J Med Chem 2018 Oct;158:25-33.
-
2018Conformational plasticity of the response regulator CpxR, a key player in Gammaproteobacteria virulence and drug-resistance, J. Struct. Biol. 2018 Nov;204(2):165-171.
-
2018ArfGAP1 restrictsentry by controlling the actin cytoskeleton, EMBO Rep. 2018 Jan;19(1):29-42.
-
2018Identification of a non-competitive inhibitor of Plasmodium falciparum aspartate transcarbamoylase., Biochem Biophys Res Commun 2018 03; 497(3): 835-842.
-
2018Serum interleukin measurement may help identify thyroid cancer patients with active disease., Clin Biochem 2018 Feb; 52(): 1-7.
-
2018Oligomeric interfaces as a tool in drug discovery: Specific interference with activity of malate dehydrogenase of Plasmodium falciparum in vitro., PLoS One 2018 ; 13(4): e0195011.
-
2017Tyrosine kinase inhibitor sensitive PDGFRΑ mutations in GIST: Two cases and review of the literature., Oncotarget 2017 Dec; 8(65): 109836-109847.
-
2017Bacterial Tubulins: A Eukaryotic-Like Microtubule Cytoskeleton, Trends Microbiol. 2017 Oct;25(10):782-784.
-
2017Mycobacterium tuberculosis Controls Phagosomal Acidification by Targeting CISH-Mediated Signaling, Cell Rep 2017 Sep;20(13):3188-3198.
-
2017Bacterial transformation: ComFA is a DNA-dependent ATPase that forms complexes with ComFC and DprA, Mol. Microbiol. 2017 Sep;105(5):741-754.
-
2017OH1 from Orf Virus: A New Tyrosine Phosphatase that Displays Distinct Structural Features and Triple Substrate Specificity, J. Mol. Biol. 2017 09;429(18):2816-2824.
-
2017A Bacterial Toxin with Analgesic Properties: Hyperpolarization of DRG Neurons by Mycolactone, Toxins (Basel) 2017 07;9(7).
-
2017Structural Coupling between Autokinase and Phosphotransferase Reactions in a Bacterial Histidine Kinase, Structure 2017 Jun;25(6):939-944.e3.
-
2017PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis., PLoS Pathog 2017 May; 13(5): e1006399.
-
2017Bacterial kinesin light chain (Bklc) links the Btub cytoskeleton to membranes., Sci Rep 2017 03; 7(): 45668.
-
2017Structure of the RZZ complex and molecular basis of its interaction with Spindly, J. Cell Biol. 2017 Apr;216(4):961-981.
-
2017The crystal structure of PknI from Mycobacterium tuberculosis shows an inactive, pseudokinase-like conformation., FEBS J 2017 02; 284(4): 602-614.
-
2017Labeling of Membrane Complexes for Electron Microscopy, Methods Mol. Biol. 2017;1635:125-138.
-
2017Drug Target Validation Methods in Malaria – Protein Interference Assay (PIA) as a Tool for Highly Specific Drug Target Validation., Curr Drug Targets 2017 ; 18(9): 1069-1085.
-
2016Modification in hydrophobic packing of HAMP domain induces a destabilization of the auto-phosphorylation site in the histidine kinase CpxA, Biopolymers 2016 Oct;105(10):670-82.
-
2016Bidirectional Allosteric Communication between the ATP-Binding Site and the Regulatory PIF Pocket in PDK1 Protein Kinase, Cell Chem Biol 2016 Sep;.
-
2016Ser/Thr Phosphorylation Regulates the Fatty Acyl-AMP Ligase Activity of FadD32, an Essential Enzyme in Mycolic Acid Biosynthesis., J Biol Chem 2016 Oct; 291(43): 22793-22805.
-
2016Crystal structure of truncated aspartate transcarbamoylase from Plasmodium falciparum., Acta Crystallogr F Struct Biol Commun 2016 07; 72(Pt 7): 523-33.
-
2016Comparative study of enzymatic activities of new KatG mutants from low- and high-level isoniazid-resistant clinical isolates of Mycobacterium tuberculosis, Tuberculosis (Edinb) 2016 09;100:15-24.
-
2016Description of compensatory gyrA mutations restoring fluoroquinolone susceptibility in Mycobacterium tuberculosis, J. Antimicrob. Chemother. 2016 May;.
-
2016Structural basis of the signalling through a bacterial membrane receptor HasR deciphered by an integrative approach, Biochem. J. 2016 07;473(14):2239-48.
-
2016Molecular Basis of Membrane Association by the Phosphatidylinositol Mannosyltransferase PimA Enzyme from Mycobacteria, J. Biol. Chem. 2016 Jul;291(27):13955-63.
-
2016Gene expression of thyroid-specific transcription factors may help diagnose thyroid lesions but are not determinants of tumor progression., J Endocrinol Invest 2016 Apr; 39(4): 423-9.
-
2016[Mycolactone: the amazing analgesic mycobacterial toxin], Med Sci (Paris) 2016 Feb;32(2):156-8.
-
2016Subtelomere organization in the genome of the microsporidian Encephalitozoon cuniculi: patterns of repeated sequences and physicochemical signatures, BMC Genomics 2016 Jan;17:34.
-
2016Synthesis and evaluation of original bioisosteres of bacterial type IIA topoisomerases inhibitors, Can. J. Chem. 2016, 94 , 240-250.
-
2015Structural Basis of Pullulanase Membrane Binding and Secretion Revealed by X-Ray Crystallography, Molecular Dynamics and Biochemical Analysis, Structure 2016 Jan;24(1):92-104.
-
2015Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG., Chem Biol 2015 Jul; 22(7): 917-27.
-
2015Molecular Basis of the Activity and the Regulation of the Eukaryotic-like S/T Protein Kinase PknG from Mycobacterium tuberculosis., Structure 2015 Jun; 23(6): 1039-48.
-
2015The crystal structure of the catalytic domain of the ser/thr kinase PknA from M. tuberculosis shows an Src-like autoinhibited conformation., Proteins 2015 May; 83(5): 982-8.
-
2015Complex assembly, crystallization and preliminary X-ray crystallographic analysis of the human Rod-Zwilch-ZW10 (RZZ) complex, Acta Crystallogr F Struct Biol Commun 2015 Apr;71(Pt 4):438-42.
-
2015Pulse Electron Double Resonance Detected Multinuclear NMR Spectra of Distant and Low Sensitivity Nuclei and Its Application to the Structure of Mn(II) Centers in Organisms, J Phys Chem B 2015 Mar;.
-
2014Secondary structure reshuffling modulates glycosyltransferase function at the membrane., Nat Chem Biol 2015 Jan; 11(1): 16-8.
-
2014Computational design of protein-based inhibitors of Plasmodium vivax subtilisin-like 1 protease, PLoS ONE 2014;9(10):e109269.
-
2014A small-molecule cell-based screen led to the identification of biphenylimidazoazines with highly potent and broad-spectrum anti-apicomplexan activity, Eur J Med Chem 2015 Jan;89:386-400.
-
2014Obesity and thyroid cancer., Endocr Relat Cancer 2014 Oct; 21(5): T255-71.
-
2014Structural studies suggest a peptidoglycan hydrolase function for the Mycobacterium tuberculosis Tat-secreted protein Rv2525c., J Struct Biol 2014 Nov; 188(2): 156-64.
-
2014Structural and mechanistic insights into the bacterial amyloid secretion channel CsgG, Nature 2014 Dec;516(7530):250-3.
-
2014A novel Plasmodium-specific prodomain fold regulates the malaria drug target SUB1 subtilase, Nat Commun 2014 Sep;5:4833.
-
2014DNA topoisomerase VIII: a novel subfamily of type IIB topoisomerases encoded by free or integrated plasmids in Archaea and Bacteria, Nucleic Acids Res. 2014 Jul;42(13):8578-91.
-
2014Mycobacterial toxin induces analgesia in buruli ulcer by targeting the angiotensin pathways, Cell 2014 Jun;157(7):1565-76.
-
2014Potent and specific inhibition of glycosidases by small artificial binding proteins (affitins), PLoS ONE 2014;9(5):e97438.
-
2014Towards elucidating the tubulin code, Nat. Cell Biol. 2014 Apr;16(4):303-5.
-
2014Cytometric measurement of in vitro inhibition of Plasmodium falciparum field isolates by drugs: a new approach for re-invasion inhibition study, Malar. J. 2014;13:110.
-
20143D cryo-electron reconstruction of BmrA, a bacterial multidrug ABC transporter in an inward-facing conformation and in a lipidic environment, J. Mol. Biol. 2014 May;426(10):2059-69.
-
2014Structure of a type IV secretion system, Nature 2014 Apr;508(7497):550-553.
-
2014Generation of a vector suite for protein solubility screening, Front Microbiol 2014;5:67.
-
2014A case of guilt by association: Water bug bite incriminated in M. ulcerans infection, Int J Mycobacteriol 2014 Jun;3(2):158-61.
-
2014A dual conformation of the post-decarboxylation intermediate is associated with distinct enzyme states in mycobacterial KGD (α-ketoglutarate decarboxylase)., Biochem J 2014 Feb; 457(3): 425-34.
-
2014Segmental helical motions and dynamical asymmetry modulate histidine kinase autophosphorylation, PLoS Biol. 2014 Jan;12(1):e1001776.
-
2014Whole Pichia pastoris yeast expressing measles virus nucleoprotein as a production and delivery system to multimerize Plasmodium antigens, PLoS ONE 2014;9(1):e86658.
-
2014Non-quinolone inhibitors of bacterial type IIA topoisomerases: a feat of bioisosterism, Chem. Rev. 2014 Feb;114(4):2313-42.
-
2014CD8+ TIL recruitment may revert the association of MAGE A3 with aggressive features in thyroid tumors., J Immunol Res 2014 ; 2014(): 921864.
-
2013A molecular marker of artemisinin-resistant Plasmodium falciparum malaria, Nature 2014 Jan;505(7481):50-5.
-
2013Inhibition of Mycobacterium tuberculosis PknG by non-catalytic rubredoxin domain specific modification: reaction of an electrophilic nitro-fatty acid with the Fe-S center., Free Radic Biol Med 2013 Dec; 65(): 150-161.
-
2013Mycobacterium tuberculosis DNA gyrase ATPase domain structures suggest a dissociative mechanism that explains how ATP hydrolysis is coupled to domain motion, Biochem. J. 2013 Dec;456(2):263-73.
-
2013Structure-function relationships of membrane-associated GT-B glycosyltransferases, Glycobiology 2014 Feb;24(2):108-24.
-
2013Mycobacterium tuberculosis DNA gyrase possesses two functional GyrA-boxes, Biochem. J. 2013 Nov;455(3):285-94.
-
2013A key role for Plasmodium subtilisin-like SUB1 protease in egress of malaria parasites from host hepatocytes, J. Biol. Chem. 2013 Nov;288(46):33336-46.
-
2013GarA is an essential regulator of metabolism in Mycobacterium tuberculosis., Mol Microbiol 2013 Oct; 90(2): 356-66.
-
2013Purification, crystallization and preliminary X-ray crystallographic studies of the Mycobacterium tuberculosis DNA gyrase ATPase domain, Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 2013 Jun;69(Pt 6):679-82.
-
2013In Silico screening on the three-dimensional model of the Plasmodium vivax SUB1 protease leads to the validation of a novel anti-parasite compound, J. Biol. Chem. 2013 Jun;288(25):18561-73.
-
2013Tolerance of the archaeal Sac7d scaffold protein to alternative library designs: characterization of anti-immunoglobulin G Affitins., Protein Eng Des Sel 2013 Apr; 26(4): 267-75.
-
2013Contactin 4, -5 and -6 differentially regulate neuritogenesis while they display identical PTPRG binding sites., Biol Open 2013 Mar; 2(3): 324-34.
-
2013Structural basis for feed-forward transcriptional regulation of membrane lipid homeostasis in Staphylococcus aureus, PLoS Pathog. 2013 Jan;9(1):e1003108.
-
2013Screening and evaluation of inhibitors of Plasmodium falciparum merozoite egress and invasion using cytometry, Methods Mol. Biol. 2013;923:523-34.
-
2013Investigation of secreted protein transcripts as early biomarkers for type 1 diabetes in the mouse model., Gene 2013 Jan; 512(1): 161-5.
-
2012Reduced artemisinin susceptibility of Plasmodium falciparum ring stages in western Cambodia, Antimicrob. Agents Chemother. 2013 Feb;57(2):914-23.
-
2012Substrate-selective inhibition of protein kinase PDK1 by small compounds that bind to the PIF-pocket allosteric docking site, Chem. Biol. 2012 Sep;19(9):1152-63.
-
2012Mechanistic insights into the retaining glucosyl-3-phosphoglycerate synthase from mycobacteria, J. Biol. Chem. 2012 Jul;287(29):24649-61.
-
2012Conformational changes upon ligand binding in the essential class II fumarase Rv1098c from Mycobacterium tuberculosis., FEBS Lett 2012 Jun; 586(11): 1606-11.
-
2012New mutations in the mycobacterial ATP synthase: new insights into the binding of the diarylquinoline TMC207 to the ATP synthase C-ring structure, Antimicrob. Agents Chemother. 2012 May;56(5):2326-34.
-
2012Structural analysis reveals features of the spindle checkpoint kinase Bub1-kinetochore subunit Knl1 interaction, J. Cell Biol. 2012 Feb;196(4):451-67.
-
2012Extending the definition of the GyrB quinolone resistance-determining region in Mycobacterium tuberculosis DNA gyrase for assessing fluoroquinolone resistance in M. tuberculosis, Antimicrob. Agents Chemother. 2012 Apr;56(4):1990-6.
-
2012Purification, crystallization and preliminary X-ray crystallographic studies of the Mycobacterium tuberculosis DNA gyrase CTD, Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 2012 Feb;68(Pt 2):178-80.
-
2011Allosteric regulation of protein kinase PKCζ by the N-terminal C1 domain and small compounds to the PIF-pocket, Chem. Biol. 2011 Nov;18(11):1463-73.
-
2011SuperPartitions: detection and classification of orthologs, Gene 2012 Jan;492(1):199-211.
-
2011Functional plasticity and allosteric regulation of α-ketoglutarate decarboxylase in central mycobacterial metabolism., Chem Biol 2011 Aug; 18(8): 1011-20.
-
2011FLP/FRT-mediated conditional mutagenesis in pre-erythrocytic stages of Plasmodium berghei, Nat Protoc 2011 Sep;6(9):1412-28.
-
2011Computational reverse-engineering of a spider-venom derived peptide active against Plasmodium falciparum SUB1, PLoS ONE 2011;6(7):e21812.
-
2011DNA gyrase inhibition assays are necessary to demonstrate fluoroquinolone resistance secondary to gyrB mutations in Mycobacterium tuberculosis, Antimicrob. Agents Chemother. 2011 Oct;55(10):4524-9.
-
2011Physiological response to membrane protein overexpression in E. coli, Mol. Cell Proteomics 2011 Oct;10(10):M111.007930.
-
20113-Keto-5-aminohexanoate cleavage enzyme: a common fold for an uncommon Claisen-type condensation., J Biol Chem 2011 Aug; 286(31): 27399-405.
-
2011Transfer on hydrophobic substrates and AFM imaging of membrane proteins reconstituted in planar lipid bilayers, J. Mol. Recognit. 2011 May-Jun;24(3):461-6.
-
2011Crystal structure of an enzymatically inactive trans-sialidase-like lectin from Trypanosoma cruzi: the carbohydrate binding mechanism involves residual sialidase activity, Biochim. Biophys. Acta 2011 Sep;1814(9):1154-61.
-
2011Crystal structure of the pyrazinamidase of Mycobacterium tuberculosis: insights into natural and acquired resistance to pyrazinamide, PLoS ONE 2011;6(1):e15785.
-
2010Crl binds to domain 2 of σ(S) and confers a competitive advantage on a natural rpoS mutant of Salmonella enterica serovar Typhi, J. Bacteriol. 2010 Dec;192(24):6401-10.
-
2010Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance., Mol Microbiol 2010 Sep; 77(5): 1172-85.
-
2010Molecular basis of phosphatidyl-myo-inositol mannoside biosynthesis and regulation in mycobacteria, J. Biol. Chem. 2010 Oct;285(44):33577-83.
-
2010Seasonal and regional dynamics of M. ulcerans transmission in environmental context: deciphering the role of water bugs as hosts and vectors, PLoS Negl Trop Dis 2010 Jul;4(7):e731.
-
2010Structural analysis of the RZZ complex reveals common ancestry with multisubunit vesicle tethering machinery, Structure 2010 May;18(5):616-26.
-
2010A novel role of malonyl-ACP in lipid homeostasis., Biochemistry 2010 Apr; 49(14): 3161-7.
-
2010Centromeric plasmids and artificial chromosomes: new kids on the Plasmodium transfection block, Cell Host Microbe 2010 Mar;7(3):181-3.
-
2010Conservation of HHV-6 DNA polymerase processivity factor sequence and predicted structure suggests it as a target for antiviral development, Antiviral Res. 2010 Jun;86(3):316-9.
-
2010Crystal structure of Mycobacterium tuberculosis LppA, a lipoprotein confined to pathogenic mycobacteria., Proteins 2010 Feb; 78(3): 769-72.
-
2009Specific structural features of the N-acetylmuramoyl-L-alanine amidase AmiD from Escherichia coli and mechanistic implications for enzymes of this family, J. Mol. Biol. 2010 Mar;397(1):249-59.
-
2009Purification, crystallization and preliminary X-ray diffraction experiments on the breakage-reunion domain of the DNA gyrase from Mycobacterium tuberculosis, Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 2009 Nov;65(Pt 11):1182-6.
-
2009Transcriptional and functional characterization of the gene encoding acyl carrier protein in Bacillus subtilis, Microbiology (Reading, Engl.) 2010 Feb;156(Pt 2):484-95.
-
2009Structural plasticity and distinct drug-binding modes of LfrR, a mycobacterial efflux pump regulator., J Bacteriol 2009 Dec; 191(24): 7531-7.
-
2009Structure of Mycobacterium tuberculosis Rv2714, a representative of a duplicated gene family in Actinobacteria., Acta Crystallogr Sect F Struct Biol Cryst Commun 2009 Oct; 65(Pt 10): 972-7.
-
2009Structural plasticity and catalysis regulation of a thermosensor histidine kinase, Proc. Natl. Acad. Sci. U.S.A. 2009 Sep;106(38):16185-90.
-
2009Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1, Nat. Chem. Biol. 2009 Oct;5(10):758-64.
-
2009Mechanisms determining cell membrane expression of different gammadelta TCR chain pairings, Eur. J. Immunol. 2009 Jul;39(7):1937-46.
-
2009GC content and recombination: reassessing the causal effects for the Saccharomyces cerevisiae genome, Genetics 2009 Sep;183(1):31-8.
-
2009Substrate-induced conformational changes in the essential peripheral membrane-associated mannosyltransferase PimA from mycobacteria: implications for catalysis, J. Biol. Chem. 2009 Aug;284(32):21613-25.
-
2009Bacterial metabolism under FHA control., Structure 2009 Apr; 17(4): 487-8.
-
2009Functional in vitro assembly of the integral membrane bacterial thermosensor DesK, Protein Expr. Purif. 2009 Jul;66(1):39-45.
-
2009Genome-wide regulon and crystal structure of BlaI (Rv1846c) from Mycobacterium tuberculosis, Mol. Microbiol. 2009 Mar;71(5):1102-16.
-
2008The FHA-containing protein GarA acts as a phosphorylation-dependent molecular switch in mycobacterial signaling, FEBS Lett. 2009 Jan;583(2):301-7.
-
2008Discovery of novel inhibitors of Trypanosoma cruzi trans-sialidase from in silico screening, Bioorg. Med. Chem. Lett. 2009 Feb;19(3):589-96.
-
2008Crystal structure and activity of Bacillus subtilis YoaJ (EXLX1), a bacterial expansin that promotes root colonization, Proc. Natl. Acad. Sci. U.S.A. 2008 Nov;105(44):16876-81.
-
2008Regulation of glutamate metabolism by protein kinases in mycobacteria., Mol Microbiol 2008 Dec; 70(6): 1408-23.
-
2008Structural insights into sialic acid enzymology, Curr Opin Chem Biol 2008 Oct;12(5):565-72.
-
2008Artificial binding proteins (Affitins) as probes for conformational changes in secretin PulD, J. Mol. Biol. 2008 Nov;383(5):1058-68.
-
2008Rising standards for tuberculosis drug development, Trends Pharmacol. Sci. 2008 Nov;29(11):576-81.
-
2008Genetic and structural insights into the dissemination potential of the extremely broad-spectrum class A beta-lactamase KPC-2 identified in an Escherichia coli strain and an Enterobacter cloacae strain isolated from the same patient in France, Antimicrob. Agents Chemother. 2008 Oct;52(10):3725-36.
-
2008Kinetic and mechanistic analysis of Trypanosoma cruzi trans-sialidase reveals a classical ping-pong mechanism with acid/base catalysis, Biochemistry 2008 Mar;47(11):3507-12.
-
2008Conformational change induced by ATP binding in the multidrug ATP-binding cassette transporter BmrA, Biochemistry 2008 Feb;47(8):2404-12.
-
2008Crystal structure of a monoclonal antibody directed against an antigenic determinant common to Ogawa and Inaba serotypes of Vibrio cholerae O1, Proteins 2008 Jan;70(1):284-8.
-
2007Structural basis for the PufX-mediated dimerization of bacterial photosynthetic core complexes, Structure 2007 Dec;15(12):1674-83.
-
2007Remodeling a DNA-binding protein as a specific in vivo inhibitor of bacterial secretin PulD, Proc. Natl. Acad. Sci. U.S.A. 2007 Nov;104(46):17983-8.
-
2007Towards new tuberculosis drugs, Biochem. Soc. Trans. 2007 Nov;35(Pt 5):1321-4.
-
2007Structural and binding studies of the three-metal center in two mycobacterial PPM Ser/Thr protein phosphatases., J Mol Biol 2007 Dec; 374(4): 890-8.
-
2007The crystal structure of Trypanosoma cruzi arginine kinase, Proteins 2007 Oct;69(1):209-12.
-
2007Heterogeneity of photosynthetic membranes from Rhodobacter capsulatus: size dispersion and ATP synthase distribution, Biochim. Biophys. Acta 2007 Nov;1767(11):1340-52.
-
2007Mycobacterial Ser/Thr protein kinases and phosphatases: physiological roles and therapeutic potential., Biochim Biophys Acta 2008 Jan; 1784(1): 193-202.
-
2007The crystal structure of M. leprae ML2640c defines a large family of putative S-adenosylmethionine-dependent methyltransferases in mycobacteria, Protein Sci. 2007 Sep;16(9):1896-904.
-
2007Genetic basis for the biosynthesis of methylglucose lipopolysaccharides in Mycobacterium tuberculosis, J. Biol. Chem. 2007 Sep;282(37):27270-6.
-
2007Nucleotide binding to human UMP-CMP kinase using fluorescent derivatives — a screening based on affinity for the UMP-CMP binding site, FEBS J. 2007 Jul;274(14):3704-14.
-
2007Insights into the catalytic mechanism of PPM Ser/Thr phosphatases from the atomic resolution structures of a mycobacterial enzyme., Structure 2007 Jul; 15(7): 863-72.
-
2007Crystal structure of the Bacillus subtilis penicillin-binding protein 4a, and its complex with a peptidoglycan mimetic peptide, J. Mol. Biol. 2007 Aug;371(2):528-39.
-
2007Molecular recognition and interfacial catalysis by the essential phosphatidylinositol mannosyltransferase PimA from mycobacteria, J. Biol. Chem. 2007 Jul;282(28):20705-14.
-
2007Influence of calcium on direct incorporation of membrane proteins into in-plane lipid bilayer, Ultramicroscopy 2007 Oct;107(10-11):928-33.
-
2007Expression and purification of an active form of the Mycobacterium leprae DNA gyrase and its inhibition by quinolones, Antimicrob. Agents Chemother. 2007 May;51(5):1643-8.
-
2007Probabilistic sequence alignments: realistic models with efficient algorithms, Phys. Rev. Lett. 2007 Feb;98(7):078101.
-
2007Protection against Mycobacterium ulcerans lesion development by exposure to aquatic insect saliva, PLoS Med. 2007 Feb;4(2):e64.
-
2007Insights into the inter-ring plasticity of caseinolytic proteases from the X-ray structure of Mycobacterium tuberculosis ClpP1, Acta Crystallogr. D Biol. Crystallogr. 2007 Feb;63(Pt 2):249-59.
-
2007Different mutations in the HHV-6 DNA polymerase gene accounting for resistance to foscarnet, Antivir. Ther. (Lond.) 2007;12(6):877-88.
-
2006The crystal structure of Rv0813c from Mycobacterium tuberculosis reveals a new family of fatty acid-binding protein-like proteins in bacteria, J. Bacteriol. 2007 Mar;189(5):1899-904.
-
2006Benzoic acid and pyridine derivatives as inhibitors of Trypanosoma cruzi trans-sialidase, Bioorg. Med. Chem. 2007 Mar;15(5):2106-19.
-
2006Evolution of proteomes: fundamental signatures and global trends in amino acid compositions, BMC Genomics 2006 Dec;7:307.
-
2006Allosteric activation of the protein kinase PDK1 with low molecular weight compounds, EMBO J. 2006 Nov;25(23):5469-80.
-
2006Structure of armadillo ACBP: a new member of the acyl-CoA-binding protein family, Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 2006 Oct;62(Pt 10):958-61.
-
2006Implementation of semi-automated cloning and prokaryotic expression screening: the impact of SPINE, Acta Crystallogr. D Biol. Crystallogr. 2006 Oct;62(Pt 10):1103-13.
-
2006Application of the use of high-throughput technologies to the determination of protein structures of bacterial and viral pathogens, Acta Crystallogr. D Biol. Crystallogr. 2006 Oct;62(Pt 10):1196-207.
-
2006SPINE bioinformatics and data-management aspects of high-throughput structural biology, Acta Crystallogr. D Biol. Crystallogr. 2006 Oct;62(Pt 10):1184-95.
-
2006The Ser/Thr protein kinase PknB is essential for sustaining mycobacterial growth, J. Bacteriol. 2006 Nov;188(22):7778-84.
-
2006Functional and structural analysis of the photosynthetic apparatus of Rhodobacter veldkampii, Biochemistry 2006 Sep;45(35):10512-20.
-
2006Formation of polymer vesicles by liquid crystal amphiphilic block copolymers, Langmuir 2006 Aug;22(18):7907-11.
-
2006Structural basis of lipid biosynthesis regulation in Gram-positive bacteria, EMBO J. 2006 Sep;25(17):4074-83.
-
2006Peroxynitrite transforms nerve growth factor into an apoptotic factor for motor neurons, Free Radic. Biol. Med. 2006 Dec;41(11):1632-44.
-
2006High-resolution AFM of membrane proteins directly incorporated at high density in planar lipid bilayer, Biophys. J. 2006 Nov;91(9):3268-75.
-
2006Continuous fluorimetric assay for high-throughput screening of inhibitors of trans-sialidase from Trypanosoma cruzi, Anal. Biochem. 2006 Oct;357(2):302-4.
-
2006Genetic basis for natural and acquired resistance to the diarylquinoline R207910 in mycobacteria, Antimicrob. Agents Chemother. 2006 Aug;50(8):2853-6.
-
2006The crystal structure of Mycobacterium tuberculosis adenylate kinase in complex with two molecules of ADP and Mg2+ supports an associative mechanism for phosphoryl transfer., Protein Sci 2006 Jun; 15(6): 1489-93.
-
2006The structure of PknB in complex with mitoxantrone, an ATP-competitive inhibitor, suggests a mode of protein kinase regulation in mycobacteria., FEBS Lett 2006 May; 580(13): 3018-22.
-
2006Molecular identification and typing of lactobacilli isolated from kefir grains, J. Dairy Res. 2006 Feb;73(1):20-7.
-
2006Crystal structure, catalytic mechanism, and mitogenic properties of Trypanosoma cruzi proline racemase, Proc. Natl. Acad. Sci. U.S.A. 2006 Feb;103(6):1705-10.
-
2005Genome trees from conservation profiles, PLoS Comput. Biol. 2005 Dec;1(7):e75.
-
2005Structural and kinetic analysis of two covalent sialosyl-enzyme intermediates on Trypanosoma rangeli sialidase, J. Biol. Chem. 2006 Feb;281(7):4149-55.
-
2005Trypanosoma cruzi proline racemases are involved in parasite differentiation and infectivity, Mol. Microbiol. 2005 Oct;58(1):46-60.
-
2005Identification of the critical residues involved in peptidoglycan detection by Nod1, J. Biol. Chem. 2005 Nov;280(46):38648-56.
-
2005Conserved autophosphorylation pattern in activation loops and juxtamembrane regions of Mycobacterium tuberculosis Ser/Thr protein kinases., Biochem Biophys Res Commun 2005 Aug; 333(3): 858-67.
-
2005Proteomic identification of M. tuberculosis protein kinase substrates: PknB recruits GarA, a FHA domain-containing protein, through activation loop-mediated interactions, J. Mol. Biol. 2005 Jul;350(5):953-63.
-
2005Crystal structure of the Actinomadura R39 DD-peptidase reveals new domains in penicillin-binding proteins, J. Biol. Chem. 2005 Sep;280(35):31249-56.
-
2005Structure and mechanism of the alkyl hydroperoxidase AhpC, a key element of the Mycobacterium tuberculosis defense system against oxidative stress, J. Biol. Chem. 2005 Jul;280(27):25735-42.
-
2005LANCL1, an erythrocyte protein recruited to the Maurer’s clefts during Plasmodium falciparum development, Mol. Biochem. Parasitol. 2005 May;141(1):39-47.
-
2005Crystallization and preliminary crystallographic analysis of PimA, an essential mannosyltransferase from Mycobacterium smegmatis, Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 2005 May;61(Pt 5):518-20.
-
2005CyProQuant-PCR: a real time RT-PCR technique for profiling human cytokines, based on external RNA standards, readily automatable for clinical use, BMC Immunol. 2005;6:5.
-
2005Glutamine amidotransferase activity of NAD+ synthetase from Mycobacterium tuberculosis depends on an amino-terminal nitrilase domain., Res Microbiol 2005 Mar; 156(2): 173-7.
-
2005A sialidase mutant displaying trans-sialidase activity, J. Mol. Biol. 2005 Jan;345(4):923-34.
-
2005Microbiology. TB–a new target, a new drug, Science 2005 Jan;307(5707):214-5.
-
2004First structural glimpse at a bacterial Ser/Thr protein phosphatase, Structure 2004 Nov;12(11):1923-4.
-
2004Characterization of a UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase with an unusual lectin domain from the platyhelminth parasite Echinococcus granulosus, Biochem. J. 2004 Sep;382(Pt 2):501-10.
-
2004Physiological ligands ADP and Pi modulate the degree of intrinsic coupling in the ATP synthase of the photosynthetic bacterium Rhodobacter capsulatus, Biochemistry 2004 Aug;43(34):11126-34.
-
2004Rv2686c-Rv2687c-Rv2688c, an ABC fluoroquinolone efflux pump in Mycobacterium tuberculosis., Antimicrob Agents Chemother 2004 Aug; 48(8): 3175-8.
-
2004Altered substrate specificity in flavocytochrome b2: structural insights into the mechanism of L-lactate dehydrogenation, Biochemistry 2004 Jul;43(29):9519-26.
-
2004Crystal structure of glycogen synthase: homologous enzymes catalyze glycogen synthesis and degradation, EMBO J. 2004 Aug;23(16):3196-205.
-
2004Structural insights into the catalytic mechanism of Trypanosoma cruzi trans-sialidase, Structure 2004 May;12(5):775-84.
-
2004GadE (YhiE): a novel activator involved in the response to acid environment in Escherichia coli, Microbiology (Reading, Engl.) 2004 Jan;150(Pt 1):61-72.
-
2004Gene targeting demonstrates that the Plasmodium berghei subtilisin PbSUB2 is essential for red cell invasion and reveals spontaneous genetic recombination events, Cell. Microbiol. 2004 Jan;6(1):65-78.
-
2003Crystallization and preliminary X-ray diffraction study of the class A beta-lactamase SED-1 and its mutant SED-G238C from Citrobacter sedlakii, Acta Crystallogr. D Biol. Crystallogr. 2004 Jan;60(Pt 1):125-8.
-
2003Sub-families of alpha/beta barrel enzymes: a new adenine deaminase family, J. Mol. Biol. 2003 Dec;334(5):1117-31.
-
2003Cervical screening in Luxembourg: 1990-1999, Cytopathology 2003 Oct;14(5):235-40.
-
2003PknB kinase activity is regulated by phosphorylation in two Thr residues and dephosphorylation by PstP, the cognate phospho-Ser/Thr phosphatase, in Mycobacterium tuberculosis, Mol. Microbiol. 2003 Sep;49(6):1493-508.
-
2003Techniques and applications: The heterologous expression of Mycobacterium tuberculosis genes is an uphill road., Trends Microbiol 2003 Aug; 11(8): 351-8.
-
2003GeneFizz: A web tool to compare genetic (coding/non-coding) and physical (helix/coil) segmentations of DNA sequences. Gene discovery and evolutionary perspectives, Nucleic Acids Res. 2003 Jul;31(13):3843-9.
-
2003Trypanosoma cruzi trans-sialidase operates through a covalent sialyl-enzyme intermediate: tyrosine is the catalytic nucleophile, J. Am. Chem. Soc. 2003 Jun;125(25):7532-3.
-
2003The Plasmodium falciparum family of Rab GTPases, Gene 2003 Mar;306:13-25.
-
2003Preliminary crystallographic studies of glycogen synthase from Agrobacterium tumefaciens, Acta Crystallogr. D Biol. Crystallogr. 2003 Mar;59(Pt 3):526-8.
-
2003The crystal structure of a plant lectin in complex with the Tn antigen, FEBS Lett. 2003 Feb;536(1-3):106-10.
-
2003Crystal structure of the catalytic domain of the PknB serine/threonine kinase from Mycobacterium tuberculosis, J. Biol. Chem. 2003 Apr;278(15):13094-100.
-
2003The high resolution structures of free and inhibitor-bound Trypanosoma rangeli sialidase and its comparison with T. cruzi trans-sialidase, J. Mol. Biol. 2003 Jan;325(4):773-84.
-
2003The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology, Tuberculosis (Edinb) 2003;83(4):223-49.
-
2002The multidrug transporters belonging to major facilitator superfamily in Mycobacterium tuberculosis., Mol Med 2002 Nov; 8(11): 714-24.
-
2002The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis, Mol. Cell 2002 Oct;10(4):757-68.
-
2002Three multigene families in Plasmodium parasites: facts and questions, Int. J. Parasitol. 2002 Oct;32(11):1323-44.
-
2002Reconstitution of T-cell receptor repertoire diversity following non-myeloablative allogeneic stem cell transplantation in an acute myeloid leukemia patient., Haematologica 2002 Oct; 87(10): ECR31.
-
2002Physical estimation of triplet phases from two new proteins, Acta Crystallogr. D Biol. Crystallogr. 2002 Oct;58(Pt 10 Pt 2):1780-6.
-
2002High prevalence of a variant of SENV in intravenous drug user HIV-infected patients., J Med Virol 2002 Sep; 68(1): 18-23.
-
2002Advantages of high-resolution phasing: MAD to atomic resolution, Acta Crystallogr. D Biol. Crystallogr. 2002 Sep;58(Pt 9):1433-41.
-
2002Heterologous expression, purification, and enzymatic activity of Mycobacterium tuberculosis NAD(+) synthetase., Protein Expr Purif 2002 Aug; 25(3): 547-57.
-
2002The crystal structure and catalytic mechanism of cellobiohydrolase CelS, the major enzymatic component of the Clostridium thermocellum Cellulosome, J. Mol. Biol. 2002 Jul;320(3):587-96.
-
2002The crystal structure of the mouse apoptosis-inducing factor AIF, Nat. Struct. Biol. 2002 Jun;9(6):442-6.
-
2002The trans-sialidase from the african trypanosome Trypanosoma brucei, Eur. J. Biochem. 2002 Jun;269(12):2941-50.
-
20021H, 13C, 15N NMR sequence-specific resonance assignment of a Clostridium thermocellum type II cohesin module, J. Biomol. NMR 2002 May;23(1):73-4.
-
2002Crystallization and preliminary X-ray analysis of the hydroperoxidase I C-terminal domain from Escherichia coli, Acta Crystallogr. D Biol. Crystallogr. 2002 May;58(Pt 5):853-5.
-
2002Crystallization and preliminary crystallographic analysis of a novel cytochrome P450 from Mycobacterium tuberculosis, Acta Crystallogr. D Biol. Crystallogr. 2002 Apr;58(Pt 4):704-5.
-
2002Induction of protective immunity by synthetic Vibrio cholerae hexasaccharide derived from V. cholerae O1 Ogawa lipopolysaccharide bound to a protein carrier, J. Infect. Dis. 2002 Apr;185(7):950-62.
-
2002Atomic (0.94 A) resolution structure of an inverting glycosidase in complex with substrate, J. Mol. Biol. 2002 Mar;316(5):1061-9.
-
2002Transmission of SEN virus from mothers to their babies., J Med Virol 2002 Mar; 66(3): 421-7.
-
2002Mapping by site-directed mutagenesis of the region responsible for cohesin-dockerin interaction on the surface of the seventh cohesin domain of Clostridium thermocellum CipA, Biochemistry 2002 Feb;41(7):2115-9.
-
2002Duplicated dockerin subdomains of Clostridium thermocellum endoglucanase CelD bind to a cohesin domain of the scaffolding protein CipA with distinct thermodynamic parameters and a negative cooperativity, Biochemistry 2002 Feb;41(7):2106-14.
-
2002Physics-based gene identification: proof of concept for Plasmodium falciparum, Bioinformatics 2002 Jan;18(1):190-3.
-
2001Novel class A beta-lactamase Sed-1 from Citrobacter sedlakii: genetic diversity of beta-lactamases within the Citrobacter genus, Antimicrob. Agents Chemother. 2001 Aug;45(8):2287-98.
-
2001Crystal structures of the class D beta-lactamase OXA-13 in the native form and in complex with meropenem, J. Mol. Biol. 2001 Jul;310(4):859-74.
-
2001Characterization of an IL-2 mimetic with therapeutic potential, Cell. Mol. Biol. (Noisy-le-grand) 2001 Jun;47(4):703-7.
-
2001Probing molecular function of trypanosomal sialidases: single point mutations can change substrate specificity and increase hydrolytic activity, Glycobiology 2001 Apr;11(4):305-11.
-
2001Epitope mapping of trans-sialidase from Trypanosoma cruzi reveals the presence of several cross-reactive determinants, Infect. Immun. 2001 Mar;69(3):1869-75.
-
2000Can isotype switch modulate antigen-binding affinity and influence clonal selection?, Eur. J. Immunol. 2000 Dec;30(12):3387-95.
-
2000Cervical cancer screening in Luxembourg, Eur. J. Cancer 2000 Nov;36(17):2240-3.
-
2000Crystal structure of an anti-carbohydrate antibody directed against Vibrio cholerae O1 in complex with antigen: molecular basis for serotype specificity, Proc. Natl. Acad. Sci. U.S.A. 2000 Jul;97(15):8433-8.
-
2000Crystal structure of the allergen Equ c 1. A dimeric lipocalin with restricted IgE-reactive epitopes, J. Biol. Chem. 2000 Jul;275(28):21572-7.
-
2000Production and functional characterization of two mouse/human chimeric antibodies with specificity for the tumor-associated Tn-antigen, Hybridoma 2000 Jun;19(3):229-39.
-
2000Analysis of the fine specificity of Tn-binding proteins using synthetic glycopeptide epitopes and a biosensor based on surface plasmon resonance spectroscopy, FEBS Lett. 2000 Mar;469(1):24-8.
-
2000Biochemical and functional characterization of the Tn-specific lectin from Salvia sclarea seeds, Eur. J. Biochem. 2000 Mar;267(5):1434-40.
-
2000The first alpha helix of interleukin (IL)-2 folds as a homotetramer, acts as an agonist of the IL-2 receptor beta chain, and induces lymphokine-activated killer cells, J. Exp. Med. 2000 Feb;191(3):529-40.
-
2000Structural basis of sialyltransferase activity in trypanosomal sialidases, EMBO J. 2000 Jan;19(1):16-24.
-
1999Plasmodium falciparum subtilisin-like protease 2, a merozoite candidate for the merozoite surface protein 1-42 maturase, Proc. Natl. Acad. Sci. U.S.A. 1999 May;96(11):6445-50.
-
1999Carbamate kinase: New structural machinery for making carbamoyl phosphate, the common precursor of pyrimidines and arginine, Protein Sci. 1999 Apr;8(4):934-40.
-
1999Crystallization and preliminary crystallographic analysis of the major horse allergen Equ c 1, Acta Crystallogr. D Biol. Crystallogr. 1999 Apr;55(Pt 4):880-2.
-
1999Use of site-directed mutagenesis to probe the structure, function and isoniazid activation of the catalase/peroxidase, KatG, from Mycobacterium tuberculosis, Biochem. J. 1999 Mar;338 ( Pt 3):753-60.
-
1999Structure of catalase-A from Saccharomyces cerevisiae, J. Mol. Biol. 1999 Feb;286(1):135-49.
-
1999Mitochondrial release of caspase-2 and -9 during the apoptotic process, J. Exp. Med. 1999 Jan;189(2):381-94.
-
1998Structural features involved in the formation of a complex between the monomeric or the dimeric form of the rev-erb beta DNA-binding domain and its DNA reactive sites, Biochemistry 1998 Aug;37(33):11488-95.
-
1998The cellulosome of Clostridium thermocellum, Biochem. Soc. Trans. 1998 May;26(2):178-85.
-
1998Phage-displayed mimotopes elicit monoclonal antibodies specific for a malaria vaccine candidate, Biol. Chem. 1998 Jan;379(1):65-70.
-
1997The carboxy-terminal C2-like domain of the alpha-toxin from Clostridium perfringens mediates calcium-dependent membrane recognition, Mol. Microbiol. 1997 Dec;26(5):867-76.
-
1997The crystal structure of a type I cohesin domain at 1.7 A resolution, J. Mol. Biol. 1997 Oct;273(3):701-13.
-
1997Plasmodium falciparum AARP1, a giant protein containing repeated motifs rich in asparagine and aspartate residues, is associated with the infected erythrocyte membrane, Infect. Immun. 1997 Aug;65(8):3003-10.
-
1997Molecular cloning of a monoclonal anti-tumor antibody specific for the Tn antigen and expression of an active single-chain Fv fragment, Hybridoma 1997 Aug;16(4):317-24.
-
1997Amino acid sequence and three-dimensional structure of the Tn-specific isolectin B4 from Vicia villosa, FEBS Lett. 1997 Jul;412(1):190-6.
-
1997The MBP fusion protein restores the activity of the first phosphatase domain of CD45, FEBS Lett. 1997 Jul;411(2-3):231-5.
-
1997Analysis of human IL-2/IL-2 receptor beta chain interactions: monoclonal antibody H2-8 and new IL-2 mutants define the critical role of alpha helix-A of IL-2, Cytokine 1997 Jul;9(7):488-98.
-
1997Crystallization and preliminary structural analysis of catalase A from Saccharomyces cerevisiae, Protein Sci. 1997 Feb;6(2):481-3.
-
1997Structural and affinity studies of IgM polyreactive natural autoantibodies, J. Immunol. 1997 Jan;158(2):968-76.
-
1996cDNA cloning and sequencing reveal the major horse allergen Equ c1 to be a glycoprotein member of the lipocalin superfamily, J. Biol. Chem. 1996 Dec;271(51):32951-9.
-
1996Interleukin 2 and its receptors: recent advances and new immunological functions, Immunol. Today 1996 Oct;17(10):481-6.
-
1996Subcloning of a DNA fragment encoding a single cohesin domain of the Clostridium thermocellum cellulosome-integrating protein CipA: purification, crystallization, and preliminary diffraction analysis of the encoded polypeptide, Protein Sci. 1996 Jun;5(6):1192-4.
-
1996Crystallization of a family 8 cellulase from Clostridium thermocellum, Proteins 1996 May;25(1):134-6.
-
1996The crystal structure of a family 5 endoglucanase mutant in complexed and uncomplexed forms reveals an induced fit activation mechanism, J. Mol. Biol. 1996 Apr;257(5):1042-51.
-
1996The crystal structure of endoglucanase CelA, a family 8 glycosyl hydrolase from Clostridium thermocellum, Structure 1996 Mar;4(3):265-75.
-
1996A potent new mode of beta-lactamase inhibition revealed by the 1.7 A X-ray crystallographic structure of the TEM-1-BLIP complex, Nat. Struct. Biol. 1996 Mar;3(3):290-7.
-
1996Crystallographic studies of antigen-antibody interactions, Methods Mol. Biol. 1996;66:11-23.
-
1995Conservative substitutions in the hydrophobic core of Rhodobacter sphaeroides thioredoxin produce distinct functional effects, Protein Sci. 1995 Dec;4(12):2510-6.
-
1995Crystal structure of a cross-reaction complex between Fab F9.13.7 and guinea fowl lysozyme, J. Biol. Chem. 1995 Jul;270(30):18067-76.
-
1995A common protein fold and similar active site in two distinct families of beta-glycanases, Nat. Struct. Biol. 1995 Jul;2(7):569-76.
-
1995Multiple crystal forms of endoglucanase CelD: signal peptide residues modulate lattice formation, J. Mol. Biol. 1995 Apr;248(2):225-32.
-
1995Structural and functional analysis of the metal-binding sites of Clostridium thermocellum endoglucanase CelD, J. Biol. Chem. 1995 Apr;270(17):9757-62.
-
1995Missense mutations in the catalase-peroxidase gene, katG, are associated with isoniazid resistance in Mycobacterium tuberculosis, Mol. Microbiol. 1995 Jan;15(2):235-45.
-
1994The human pre-B cell receptor: structural constraints for a tentative model of the pseudo-light (psi L) chain, Mol. Immunol. 1994 Oct;31(14):1099-108.
-
1994Characterization of two crystal forms of Clostridium thermocellum endoglucanase CelC, Proteins 1994 Jun;19(2):158-60.
-
1994Crystal structures of pheasant and guinea fowl egg-white lysozymes, Protein Sci. 1994 May;3(5):788-98.
-
1994Three-dimensional structure of rat liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase: a member of the aldo-keto reductase superfamily, Proc. Natl. Acad. Sci. U.S.A. 1994 Mar;91(7):2517-21.
-
1994Crystallization and preliminary diffraction analysis of the catalytic domain of xylanase Z from Clostridium thermocellum, J. Mol. Biol. 1994 Jan;235(4):1348-50.
-
1994Structural implications of somatic mutations during the immune response to 2-phenyloxazolone, Res. Immunol. 1994 Jan;145(1):41-5.
-
1993Three-dimensional structure of a heteroclitic antigen-antibody cross-reaction complex, Proc. Natl. Acad. Sci. U.S.A. 1993 Aug;90(16):7711-5.
-
1993Crystallization and preliminary crystallographic analysis of a tetrameric isolectin from Vicia villosa, specific for the Tn antigen, J. Mol. Biol. 1993 Mar;230(2):670-2.
-
1993Crystallization, preliminary X-ray diffraction study, and crystal packing of a complex between anti-hen lysozyme antibody F9.13.7 and guinea-fowl lysozyme, Proteins 1993 Feb;15(2):209-12.
-
1992Three-dimensional structure of two crystal forms of FabR19.9 from a monoclonal anti-arsonate antibody, Proc. Natl. Acad. Sci. U.S.A. 1992 Oct;89(20):9429-33.
-
1991The three-dimensional structure of the aspartyl protease from the HIV-1 isolate BRU, Biochimie 1991 Nov;73(11):1391-6.
-
1991Cloning and sequencing of PYBP, a pyrimidine-rich specific single strand DNA-binding protein, Nucleic Acids Res. 1991 Oct;19(19):5237-45.
-
1991Crystallization and preliminary X-ray diffraction data of the Fab fragment of a monoclonal antibody against apamin, a bee venom neurotoxin, FEBS Lett. 1991 Jul;286(1-2):64-6.
-
1990Resolution of hypervariable regions in T-cell receptor beta chains by a modified Wu-Kabat index of amino acid diversity, Proc. Natl. Acad. Sci. U.S.A. 1990 Dec;87(23):9138-42.
-
1990Three-dimensional structure determination of an anti-2-phenyloxazolone antibody: the role of somatic mutation and heavy/light chain pairing in the maturation of an immune response, EMBO J. 1990 Dec;9(12):3807-14.
-
1990Poly(Glu60Ala30Tyr10) (GAT)-induced IgG monoclonal antibodies cross-react with various self and non-self antigens through the complementarity determining regions. Comparison with IgM monoclonal polyreactive natural antibodies, Eur. J. Immunol. 1990 Nov;20(11):2383-7.
-
1989Studies of structure and specificity of some antigen-antibody complexes, Philos. Trans. R. Soc. Lond., B, Biol. Sci. 1989 Jun;323(1217):487-94.
-
1989The protein encoded by a murine male germ cell-specific transcript is a putative ATP-dependent RNA helicase, Cell 1989 May;57(4):549-59.
-
1989Three-dimensional structure of Fab R19.9, a monoclonal murine antibody specific for the p-azobenzenearsonate group, Proc. Natl. Acad. Sci. U.S.A. 1989 Jan;86(2):607-11.
-
1988Three-dimensional structure of antibodies, Annu. Rev. Immunol. 1988;6:555-80.
-
1987Preliminary crystallographic study of a complex between an heteroclitic anti-hen egg-white lysozyme antibody and the heterologous antigen pheasant egg-white lysozyme, J. Mol. Biol. 1987 Sep;197(2):375-6.
-
1986Preliminary crystallographic study of the Fab fragment of a monoclonal antibody directed against a cobra cardiotoxin, J. Mol. Biol. 1986 Jun;189(4):723-4.
-
1986Crystallization and preliminary X-ray diffraction study of an endoglucanase from Clostridium thermocellum, J. Mol. Biol. 1986 May;189(1):249-50.