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© Institut Pasteur
Cells infected for 24 hrs with C. Trachomatis. The cell nuclei are labelled in blue, the bacteria appear yellow, within the inclusion lumen. A bacterial protein secreted out the inclusion into the host cytoplasm id labelled in red.
Publication : Biochemical Society transactions

Towards new tuberculosis drugs

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Biochemical Society transactions - 01 Nov 2007

Cole ST, Alzari PM

Link to Pubmed [PMID] – 17956342

Biochem. Soc. Trans. 2007 Nov;35(Pt 5):1321-4

The need for better drugs to treat tuberculosis has never been greater. Despite insufficient funding for discovery research, intensive efforts have been made to find and develop new lead compounds capable of reducing the duration of the present treatment known as DOTS (directly observed therapy short course), from 6 to under 4 months. This minireview describes the progress achieved during the last 5 years and highlights some of the successes without neglecting the problems.

http://www.ncbi.nlm.nih.gov/pubmed/17956342