I am a medical epidemiologist (MD in 1988 at Paris V, specialisation in rheumatology in 1990, Paris V, and DrPH from Harvard School of Public Health in 1993) specialized in infectious diseases epidemiology. After working at WHO at the clinical research unit of the Global Program on AIDS (1993-1994), I spent five years in Ethiopia and two years in the Netherlands working as the Program Manager of the Ethio-Netherlands AIDS Research Project (1994-2001). In 2002, I joined Institut Pasteur to launch the Emerging Diseases Epidemiology unit. There, my focus has been on viral hepatitis C (North-Coordinator of the ANRS research site on viral hepatitis; www.hepnile.org) and emerging infections such as the SARS (Scientific Coordinator of the EPISARS project which aimed prevent the re-emergence of SARS through the control of its animal reservoir) and the MERS-CoV. I also have a strong teaching involvement, as co-Director and founder of the Pasteur-Cnam School of Public Health (http://ecole-pasteur.cnam.fr), and coordinator of a master in public health with strong focus on infectious diseases. In 2014, I was appointed as Director of the newly created Pasteur Centre for Global Health Research and Education.
Emerging Infectious Diseases
Ever since its very early days, the Institut Pasteur has been committed to tackling emerging infections, and its work has left an extraordinary legacy. Many emerging infectious diseases are zoonoses, in which an animal […]
INCEPTION – Institut Convergence for the study of Emergence of Pathology Through Individuals and Populations
IINCEPTION Goal The Inception aims to develop a core structure to mobilize data resources, numerical sciences, and fundamental experimental biology in various health issues (Official website here: https://www.inception-program.fr/en). The inception program uses Integrative Biology, […]
The Healthy Human Global Project
Susceptibility to infections, disease progression and severity, and response to medical therapies and vaccines are highly variable from one individual to another. The complexity of individual immune responses is such that it has not […]
LabEx IBEID – Integrative Biology of Emerging Infectious Diseases
Presentation The aim of the Integrative Biology of Emerging Infectious Diseases (IBEID) project, coordinated by Professors Philippe Sansonetti and Pascale Cossart and currently coordinated by Carla Saleh and Philippe Bastin, is to develop a […]
Longitudinal follow-up of a population cohort in a French city with high SARS-CoV-2 circulation in early 2020 : the COVID-Oise cohort
(Last update: 10/10/2023) Context In early 2020, the first French death attributed to the SARS-CoV-2 virus was a teacher from Crépy-en-Valois, a city north of Paris. The intense circulation of the novel coronavirus in […]
Quantifying the health impacts of Zika virus infection
Previously considered to cause limited human infection and mild disease, Zika virus (ZIKV) caused several large outbreaks in Yap Island in 2007, in French Polynesia in 2013-2014 and the 2015-2016 epidemic across the Americas […]
ComCor: Study of sociodemographic factors, behaviors and practices associated with SARS-CoV-2 infection
The ComCor study is a nationwide case-control study which aims first to describe the locations and circumstances of recent SARS-CoV-2 infection, and second, to assess the role of different settings and activities in the […]
AFRIPOX – A One Health approach of monkeypox in Centrafrican Republic
Monkeypox is an emerging Orthopoxvirus responsible for monkeypox disease, clinically similar to smallpox with a lethality of around 1 to 10%. This disease is a zoonosis initially transmitted from an animal reservoir and then […]
Protected: Pasteur Human Genome
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ANRS 12332 HepNile: Evaluation of “Real Life” Efficacy and Safety of antiviral treatments including new Direct Antiviral Agents among patients treated for Chronic Hepatitis C at Egyptian National Treatment Centres
Background: Clinical trials are performed under optimal conditions where patients are highly selected without co-morbidities, clinical supervision is provided by specialists, and strict protocols are used to enhance patient compliance. Due to this, results […]
HCV research in Egypt
Funding: ANRS & EC. The main research objectives of this multidisciplinary network funded by the ANRS and the EC are the assessment of the burden of HCV infection and disease in Egypt, the study […]
Epidemiology of Buruli ulcer in Cameroon
Funding: ANR, Fondation Raoul Follereau, Fondation SANOFI Espoir. In this new research program, we will conduct for the first time the simultaneous collection of environmental (plants and insects) and human samples in two […]
Acute Bacterial Meningitis Project: Investigation of the spatio-temporal dynamics of meningitis epidemics in Niger and the associated ecologic risk factors
Funding : DCI Monaco. In collaboration with epidemiologists from the Centre de Recherche Médicale et Sanitaire (CERMES) in Niamey, we are using recent advances in Geographic Information Systems and statistical methodology to investigate […]
2023Risk of SARS-CoV-2 Infection Among Households With Children in France, 2020-2022., JAMA Netw Open 2023 Sep; 6(9): e2334084.
2023Investigation of a mpox outbreak in Central African Republic, 2021-2022., One Health 2023 Jun; 16(): 100523.
2023Estimated protection against COVID-19 based on predicted neutralisation titres from multiple antibody measurements in a longitudinal cohort, France, April 2020 to November 2021., Euro Surveill 2023 Jun; 28(25): .
2023SARS-CoV-2 self-test uptake and factors associated with self-testing during Omicron BA.1 and BA.2 waves in France, January to May 2022., Euro Surveill 2023 May; 28(18): .
2023SARS-CoV-2 incubation period across variants of concern, individual factors, and circumstances of infection in France: a case series analysis from the ComCor study., Lancet Microbe 2023 Apr; (): .
2023Rapid emergence of extensively drug-resistant Shigella sonnei in France., Nat Commun 2023 Jan; 14(1): 462.
2022Consequences of In Utero Zika Virus Exposure and Adverse Pregnancy and Early Childhood Outcomes: A Prospective Cohort Study., Viruses 2022 Dec; 14(12): .
2022National Monkeypox Surveillance, Central African Republic, 2001-2021., Emerging Infectious Diseases, 2022, 28 (12), pp.2435-2445. ⟨10.3201/eid2812.220897⟩.
2022Neutralising antibody responses to SARS-CoV-2 omicron among elderly nursing home residents following a booster dose of BNT162b2 vaccine: A community-based, prospective, longitudinal cohort study., EClinicalMedicine 2022 Sep; 51(): 101576.
2022Epidemiological evidence of nosocomial and zoonotic transmission of HTLV-1 in a large survey in rural population of central Africa., J Infect Dis 2022 Jul; (): .
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