I am a medical epidemiologist (MD in 1988 at Paris V, specialisation in rheumatology in 1990, Paris V, and DrPH from Harvard School of Public Health in 1993) specialized in infectious diseases epidemiology. After working at WHO at the clinical research unit of the Global Program on AIDS (1993-1994), I spent five years in Ethiopia and two years in the Netherlands working as the Program Manager of the Ethio-Netherlands AIDS Research Project (1994-2001). In 2002, I joined Institut Pasteur to launch the Emerging Diseases Epidemiology unit. There, my focus has been on viral hepatitis C (North-Coordinator of the ANRS research site on viral hepatitis; www.hepnile.org) and emerging infections such as the SARS (Scientific Coordinator of the EPISARS project which aimed prevent the re-emergence of SARS through the control of its animal reservoir) and the MERS-CoV. I also have a strong teaching involvement, as co-Director and founder of the Pasteur-Cnam School of Public Health (http://ecole-pasteur.cnam.fr), and coordinator of a master in public health with strong focus on infectious diseases. In 2014, I was appointed as Director of the newly created Pasteur Centre for Global Health Research and Education.
Emerging Infectious Diseases
Ever since its very early days, the Institut Pasteur has been committed to tackling emerging infections, and its work has left an extraordinary legacy. Many emerging infectious diseases are zoonoses, in which an animal […]
INCEPTION – Institut Convergence for the study of Emergence of Pathology Through Individuals and Populations
IINCEPTION Goal The Inception’s goal is to develop a core structure to mobilize data resources, numerical sciences, and fundamental experimental biology in a range of health issues (Official website here : https://www.inception-program.fr/en). Inception program […]
The Healthy Human Global Project
Susceptibility to infections, disease progression and severity, and response to medical therapies and vaccines are highly variable from one individual to another. The complexity of individual immune responses is such that it has not […]
LabEx IBEID – Integrative Biology of Emerging Infectious Diseases
Presentation The aim of the Integrative Biology of Emerging Infectious Diseases (IBEID) project, coordinated by Professors Philippe Sansonetti and Pascale Cossart, is to develop a structure to anticipate and tackle emerging infectious diseases (EIDs). […]
Longitudinal follow-up of a population cohort in a French city with high SARS-CoV-2 circulation in early 2020 : the COVID-Oise cohort
Context In early 2020, the first French death attributed to the SARS-CoV-2 virus was a teacher from Crépy-en-Valois, a city north of Paris. The intense circulation of the novel coronavirus in that area was […]
Quantifying the health impacts of Zika virus infection
Previously considered to cause limited human infection and mild disease, Zika virus (ZIKV) caused several large outbreaks in Yap Island in 2007, in French Polynesia in 2013-2014 and the 2015-2016 epidemic across the Americas […]
ComCor: Study of sociodemographic factors, behaviors and practices associated with SARS-CoV-2 infection
The ComCor study is a nationwide case-control study which aims first to describe the locations and circumstances of recent SARS-CoV-2 infection, and second, to assess the role of different settings and activities in the […]
AFRIPOX – A One Health approach of monkeypox in Centrafrican Republic
AFRIPOX : une approche One Health de la variole du singe en République Centrafricaine : Infection humaine, reservoir animal, écologie de la maladie et outils diagnostiques Le monkeypox est un Orthopoxvirus émergent responsable de […]
Protected: Pasteur Human Genome
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ANRS 12332 HepNile: Evaluation of “Real Life” Efficacy and Safety of antiviral treatments including new Direct Antiviral Agents among patients treated for Chronic Hepatitis C at Egyptian National Treatment Centres
Background: Clinical trials are performed under optimal conditions where patients are highly selected without co-morbidities, clinical supervision is provided by specialists, and strict protocols are used to enhance patient compliance. Due to this, results […]
HCV research in Egypt
Funding: ANRS & EC. The main research objectives of this multidisciplinary network funded by the ANRS and the EC are the assessment of the burden of HCV infection and disease in Egypt, the study […]
Epidemiology of Buruli ulcer in Cameroon
Funding: ANR, Fondation Raoul Follereau, Fondation SANOFI Espoir. In this new research program, we will conduct for the first time the simultaneous collection of environmental (plants and insects) and human samples in two […]
Acute Bacterial Meningitis Project: Investigation of the spatio-temporal dynamics of meningitis epidemics in Niger and the associated ecologic risk factors
Funding : DCI Monaco. In collaboration with epidemiologists from the Centre de Recherche Médicale et Sanitaire (CERMES) in Niamey, we are using recent advances in Geographic Information Systems and statistical methodology to investigate […]
2022Impact of booster vaccination on the control of COVID-19 Delta wave in the context of waning immunity: application to France in the winter 2021/22., Euro Surveill 2022 01; 27(1): .
2021Impact of SARS-CoV-2 Delta variant on incubation, transmission settings and vaccine effectiveness: Results from a nationwide case-control study in France., Lancet Reg Health Eur 2021 Nov; (): 100278.
2021SARS-CoV-2 transmission across age groups in France and implications for control., Nat Commun 2021 11; 12(1): 6895.
2021Kinetics of the Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Response and Serological Estimation of Time Since Infection., J Infect Dis 2021 11; 224(9): 1489-1499.
2021Impact of original, B.1.1.7, and B.1.351/P.1 SARS-CoV-2 lineages on vaccine effectiveness of two doses of COVID-19 mRNA vaccines: Results from a nationwide case-control study in France., Lancet Reg Health Eur 2021 Sep; 8(): 100171.
2021Evolution of antibody responses up to 13 months after SARS-CoV-2 infection and risk of reinfection., EBioMedicine 2021 Aug; 71(): 103561.
2021Exposures associated with SARS-CoV-2 infection in France: A nationwide online case-control study., Lancet Reg Health Eur 2021 Aug; 7(): 100148.
2021A modelling study investigating short and medium-term challenges for COVID-19 vaccination: From prioritisation to the relaxation of measures., EClinicalMedicine 2021 Aug; 38(): 101001.
2021Education and mental health: good reasons to vaccinate children., Lancet 2021 07; 398(10298): 387.
2021Humoral immunity to SARS-CoV-2 and seasonal coronaviruses in children and adults in north-eastern France., EBioMedicine 2021 Aug; 70(): 103495.
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