Courses
Emerging and re-emerging viruses MOOC
This MOOC aims to provide fundamental knowledge about the emerging and re-emerging viruses involved in outbreaks. It illustrates the latest knowledge about the current SARS-CoV-2-Covid-19 pandemic. Register on: https://www.fun-mooc.fr/en/courses/emerging-and-re-emerging-viruses/ Emerging and re-emerging viruses are […]
MOOC Viruses and Human Cancers
The MOOC offers a broad overview of the state of knowledge on viruses associated with cancer, the different mechanisms of carcinogenesis, the host immune response and progress in preventing tumors. Registration on: https://www.fun-mooc.fr/en/courses/viruses-and-human-cancers/ […]
Transversal Projects
Publications
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2022APOBEC3C S188I polymorphism enhances context specific editing of Hepatitis B virus genome., J Infect Dis 2022 Jan; (): .
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2021Frame-shifted APOBEC3A encodes two alternative pro-apoptotic proteins that target the mitochondrial network., J Biol Chem 2021 Aug; (): 101081.
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2019Hypoxia-induced human deoxyribonuclease I is a cellular restriction factor of hepatitis B virus, Nat Microbiol 2019 07;4(7):1196-1207.
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2019Genotoxic stress increases cytoplasmic mitochondrial DNA editing by human APOBEC3 mutator enzymes at a single cell level, Sci Rep 2019 Feb;9(1):3109.
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2019Elephant APOBEC3A cytidine deaminase induces massive double-stranded DNA breaks and apoptosis, Sci Rep 2019 Jan;9(1):728.
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2018The rabbit as an orthologous small animal model for APOBEC3A oncogenesis, Oncotarget 2018 Jun;9(45):27809-27822.
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2014ADAR1 enhances HTLV-1 and HTLV-2 replication through inhibition of PKR activity, Retrovirology 2014;11:93.
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2014A prevalent cancer susceptibility APOBEC3A hybrid allele bearing APOBEC3B 3’UTR enhances chromosomal DNA damage, Nat Commun 2014;5:5129.
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2013Orthologous mammalian APOBEC3A cytidine deaminases hypermutate nuclear DNA, Mol. Biol. Evol. 2014 Feb;31(2):330-40.
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2013Human APOBEC3A isoforms translocate to the nucleus and induce DNA double strand breaks leading to cell stress and death, PLoS ONE 2013;8(8):e73641.
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