Christian Bréchot holds MD Ph.D degrees. Beginning in 1981 he studied molecular biology, virology, and cellular biology at the laboratory of Pierre Tiollais at the Pasteur Institute, and at the Necker Faculty of Medicine; he obtained his Ph.D in biochemistry from the University of Paris VII in 1985.
In 1989 he became full professor of Cell Biology and Hepatology, and in 1997 he was appointed head of the clinical department of liver diseases at the Necker-Enfants Malades Hospital. He has been in charge of a research unit at the Necker Faculty of Medicine, jointly supported by Inserm (the French national biomedical research agency), Paris Descartes University, and the Pasteur Institute; he was also head of the National Reference Centre on viral hepatitis from 1998 to 2001.
From 2001 to 2007, Christian Bréchot has acted as General Director of Inserm, the French National Agency for biomedical research.
From 2008, he has been appointed as Vice-president in charge of Medical and Scientific affairs of the Institut Merieux company. Institut Merieux is a holding company which merges the efforts of four companies involved in in vitro diagnostics, preventive and therapeutic vaccines, as well as food safety (Biomérieux, Transgene, Merieux Nutrisciences, Advanced Bioscience Laboratory).
Christian Bréchot’s research has been mainly focussed on viral hepatitis: hepatitis B (HBV) and C (HCV), particularly with regard to their role in liver cancer (Hepatocellular carcinoma: HCC) and to the molecular mechanisms that drive liver regeneration and cancer (in particular, cell cycle deregulation).
Christian Bréchot has been the member of numerous scientific committees and societies and has received prestigious awards. Overall, he is the author of over 350 articles published in medical and scientific journals. In addition, his research activities have led him to obtain 13 patents and to contribute to the creation of two biotech companies : Rarecells and ALFACT Innovation.