I am a medical epidemiologist (MD in 1988 at Paris V, specialisation in rheumatology in 1990, Paris V, and DrPH from Harvard School of Public Health in 1993) specialized in infectious diseases epidemiology. After working at WHO at the clinical research unit of the Global Program on AIDS (1993-1994), I spent five years in Ethiopia and two years in the Netherlands working as the Program Manager of the Ethio-Netherlands AIDS Research Project (1994-2001). In 2002, I joined Institut Pasteur to launch the Emerging Diseases Epidemiology unit. There, my focus has been on viral hepatitis C (North-Coordinator of the ANRS research site on viral hepatitis; www.hepnile.org) and emerging infections such as the SARS (Scientific Coordinator of the EPISARS project which aimed prevent the re-emergence of SARS through the control of its animal reservoir) and the MERS-CoV. I also have a strong teaching involvement, as co-Director and founder of the Pasteur-Cnam School of Public Health (http://ecole-pasteur.cnam.fr), and coordinator of a master in public health with strong focus on infectious diseases. In 2014, I was appointed as Director of the newly created Pasteur Centre for Global Health Research and Education.
INCEPTION – INstitut Convergences pour l’étude de l’Émergence des Pathologies au Travers des Individus et des populatiONs et des
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Emergency response to global threats of emerging and re-emerging pathogens
With over 125 years’ experience with infectious diseases, the Institut Pasteur and the Institut Pasteur International Network (IPIN), which is composed of 33 research institutes in 26 countries and five continents, are ideally positioned […]
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ANRS 12332 HepNile: Evaluation of “Real Life” Efficacy and Safety of antiviral treatments including new Direct Antiviral Agents among patients treated for Chronic Hepatitis C at Egyptian National Treatment Centres
Background: Clinical trials are performed under optimal conditions where patients are highly selected without co-morbidities, clinical supervision is provided by specialists, and strict protocols are used to enhance patient compliance. Due to this, results […]
HCV research in Egypt
Funding: ANRS & EC. The main research objectives of this multidisciplinary network funded by the ANRS and the EC are the assessment of the burden of HCV infection and disease in Egypt, the study […]
Epidemiology of Buruli ulcer in Cameroon
Funding: ANR, Fondation Raoul Follereau, Fondation SANOFI Espoir. In this new research program, we will conduct for the first time the simultaneous collection of environmental (plants and insects) and human samples in two […]
Acute Bacterial Meningitis Project: Investigation of the spatio-temporal dynamics of meningitis epidemics in Niger and the associated ecologic risk factors
Funding : DCI Monaco. In collaboration with epidemiologists from the Centre de Recherche Médicale et Sanitaire (CERMES) in Niamey, we are using recent advances in Geographic Information Systems and statistical methodology to investigate […]
2018Hypoglycemic Toxins and Enteroviruses as Causes of Outbreaks of Acute Encephalitis-Like Syndrome in Children, Bac Giang Province, Northern Vietnam, Emerging Infect. Dis. 2018 Aug;24(8):1435-1443.
2018Letter: concordance of SVR4 and SVR12 following direct-acting anti-viral treatment in Egypt, Aliment. Pharmacol. Ther. 2018 Jun;47(11):1564-1566.
2018Poor Sensitivity of Commercial Rapid Diagnostic Tests for Hepatitis B e Antigen in Senegal, West Africa, Am. J. Trop. Med. Hyg. 2018 Aug;99(2):428-434.
2018A multi-faceted pandemic: a review of the state of knowledge on the Zika virus, Public Health Rev 2018;39:10.
2018Risk of hepatitis B virus reactivation with direct-acting antivirals against hepatitis C virus: A cohort study from Egypt and meta-analysis of published data, Liver Int. 2018 May;.
2018The burden of hepatitis C virus in Cameroon: Spatial epidemiology and historical perspective, J. Viral Hepat. 2018 08;25(8):959-968.
2018Development and clinical validation of the Genedrive point-of-care test for qualitative detection of hepatitis C virus, Gut 2018 Apr;.
2018Pregnancy Outcomes after ZIKV Infection in French Territories in the Americas, N. Engl. J. Med. 2018 03;378(11):985-994.
2018Prosthetic Valve Candida spp. Endocarditis: New Insights Into Long-term Prognosis-The ESCAPE Study, Clin. Infect. Dis. 2018 Mar;66(6):825-832.
2018Increased recurrence rates of hepatocellular carcinoma after DAA therapy in a hepatitis C-infected Egyptian cohort: A comparative analysis, J. Viral Hepat. 2018 06;25(6):623-630.
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