Timeline

Romain Koszul
Head of Structure
21 Mar 2024
publication

Sister chromatid cohesion halts DNA loop expansion.

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05 Feb 2024
publication

Orchestrating chromosome conformation capture analysis with Bioconductor.

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04 Jan 2024
publication

Transcription-induced domains form the elementary constraining building blocks of bacterial chromosomes.

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24 Nov 2023
news

Congratulation to Romain Koszul for being awarded the Molecular and Cellular Biology, Genomics Medal of the Academie des Sciences

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22 Nov 2023
publication

Design, construction, and functional characterization of a tRNA neochromosome in yeast.

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08 Nov 2023
publication

Synthetic chromosome fusion: Effects on mitotic and meiotic genome structure and function.

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09 Oct 2023
project

AFRIBIOTA 2

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01 Oct 2023
publication

Insights in bacterial genome folding.

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26 Jul 2023
publication

Neuroinvasion and anosmia are independent phenomena upon infection with SARS-CoV-2 and its variants.

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19 May 2023
publication

Chromosome folding and prophage activation reveal specific genomic architecture for intestinal bacteria.

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01 Nov 2022
publication

Chromosomal assembly of the flat oyster (Ostrea edulis L.) genome as a new genetic resource for aquaculture.

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05 Oct 2022
publication

Depletion or cleavage of cohesin during anaphase differentially affects chromatin structure and segregation.

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15 Sep 2022
publication

Chromosome-scale assemblies of Acanthamoeba castellanii genomes provide insights into Legionella pneumophila infection-related chromatin reorganization.

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10 Aug 2022
publication

Karyotype engineering reveals spatio-temporal control of replication firing and gene contacts.

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07 Jul 2022
news

Romain Koszul nominated as a new EMBO member

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01 Jun 2022
publication

Smc3 acetylation, Pds5 and Scc2 control the translocase activity that establishes cohesin-dependent chromatin loops.

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21 Mar 2022
publication

Extended sister-chromosome catenation leads to massive reorganization of the E. coli genome.

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21 Feb 2022
publication

Crosstalk between Hepatitis B Virus and the 3D Genome Structure.

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01 Jan 2022
publication

Normalization of Chromosome Contact Maps: Matrix Balancing and Visualization.

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01 Jan 2022
publication

Metagenomes Binning Using Proximity-Ligation Data.

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17 Nov 2021
news

Romain Koszul and Martial Marbouty discuss the use of 3C to understand phage-bacteria interaction on La Méthode Scientifique – France Culture

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01 Nov 2021
publication

Cohesin regulates homology search during recombinational DNA repair.

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08 Oct 2021
publication

Chromosome-level genome assembly reveals homologous chromosomes and recombination in asexual rotifer Adineta vaga.

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18 Jun 2021
publication

Generation of gene-level resolution chromosome contact maps in bacteria and archaea.

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29 Apr 2021
publication

Closed and High-Quality Bacterial Genome Sequences of the Oligo-Mouse-Microbiota Community.

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26 Feb 2021
publication

MetaHiC phage-bacteria infection network reveals active cycling phages of the healthy human gut.

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12 Feb 2021
publication

Sir3 mediates long-range chromosome interactions in budding yeast.

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22 Jan 2021
publication

Chromosomal scale assembly of parasitic wasp genome reveals symbiotic virus colonization.

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22 Dec 2020
publication

Euryarchaeal genomes are folded into SMC-dependent loops and domains, but lack transcription-mediated compartmentalization.

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16 Nov 2020
publication

Computer vision for pattern detection in chromosome contact maps.

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21 Jul 2020
software

instaGRAAL: chromosome-level quality scaffolding of genomes using a proximity ligation-based scaffolder

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21 Jul 2020
software

Chromosight: A computer vision program for pattern detection in chromosome contact maps

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21 Jul 2020
software

Serpentine: a flexible 2D binning method for differential Hi-C analysis

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21 Jul 2020
project

ERC-2017-COG Synarchic – Investigating the functional architecture of microbial genomes with synthetic approaches

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18 Jun 2020
publication

instaGRAAL: chromosome-level quality scaffolding of genomes using a proximity ligation-based scaffolder.

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01 Jun 2020
publication

Serpentine: a flexible 2D binning method for differential Hi-C analysis.

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20 Mar 2020
publication

Chromosome organization by a conserved condensin-ParB system in the actinobacterium Corynebacterium glutamicum.

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28 Jan 2020
publication

Regulation of Cohesin-Mediated Chromosome Folding by Eco1 and Other Partners

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18 Dec 2019
publication

Perspectives on Chromosome Organization

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03 Oct 2019
publication

FACT mediates cohesin function on chromatin

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20 Aug 2019
publication

MetaTOR: A Computational Pipeline to Recover High-Quality Metagenomic Bins From Mammalian Gut Proximity-Ligation (meta3C) Libraries

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30 May 2019
publication

Condensin-Mediated Chromosome Folding and Internal Telomeres Drive Dicentric Severing by Cytokinesis

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21 Feb 2019
event

François Jacob Conference

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05 Feb 2019
publication

Dynamic Processing of Displacement Loops during Recombinational DNA Repair

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15 Oct 2018
publication

Tridimensional infiltration of DNA viruses into the host genome shows preferential contact with active chromatin.

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18 Sep 2018
publication

Generation of a Metagenomics Proximity Ligation 3C Library of a Mammalian Gut Microbiota

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03 Aug 2018
publication

Kinetic Signature of Cooperativity in the Irreversible Collapse of a Polymer

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16 Jul 2018
publication

Characterizing meiotic chromosomes’ structure and pairing using a designer sequence optimized for Hi-C

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24 Feb 2018
publication

A Proximity Ligation-Based Method for Quantitative Measurement of D-Loop Extension in S. cerevisiae

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10 Jan 2018
publication

Multiscale Structuring of the E. coli Chromosome by Nucleoid-Associated and Condensin Proteins

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20 Jul 2017
publication

Cohesins and condensins orchestrate the 4D dynamics of yeast chromosomes during the cell cycle

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12 Jun 2017
publication

Proximity ligation scaffolding and comparison of two Trichoderma reesei strains genomes

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10 Mar 2017
publication

3D organization of synthetic and scrambled chromosomes

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10 Mar 2017
publication

Deep functional analysis of synII, a 770-kilobase synthetic yeast chromosome

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17 Feb 2017
publication

Scaffolding bacterial genomes and probing host-virus interactions in gut microbiome by proximity ligation (chromosome capture) assay

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01 Jan 2017
publication

Generation and Analysis of Chromosomal Contact Maps of Bacteria

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08 Jun 2016
publication

Beyond the bounds of evolution: Synthetic chromosomes… How and what for?

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01 Apr 2016
publication

A checkpoint control orchestrates the replication of the two chromosomes of Vibrio cholerae.

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05 Jan 2016
publication

Evidence for actin dual role in regulating chromosome organization and dynamics in yeast

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01 Jan 2016
publication

Generation and Analysis of Chromosomal Contact Maps of Yeast Species

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24 Nov 2015
publication

The 3D folding of metazoan genomes correlates with the association of similar repetitive elements

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19 Nov 2015
publication

Metagenome Analysis Exploiting High-Throughput Chromosome Conformation Capture (3C) Data

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09 Nov 2015
project

ERC-2010-StG Interaction dynamique entre chromosomes eucaryotes : impact sur la stabilité du génome (DICIG)

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01 Oct 2015
publication

Conception et synthèse de néochromosomes

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23 Sep 2015
publication

Spatial reorganization of telomeres in long-lived quiescent cells.

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11 Sep 2015
software

GRAAL: genome assembly from chromosome contact frequencies

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02 Sep 2015
publication

Genome-wide replication landscape of Candida glabrata

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21 Aug 2015
publication

Filling the gap: Micro-C accesses the nucleosomal fiber at 100-1000 bp resolution

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15 Jun 2015
software

META3C (MetaHiC), metaTOR

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11 May 2015
team

Spatial Regulation of Genomes

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29 Apr 2015
publication

Contact genomics: scaffolding and phasing (meta)genomes using chromosome 3D physical signatures

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25 Jan 2015
publication

Condensin- and Replication-Mediated Bacterial Chromosome Folding and Origin Condensation Revealed by Hi-C and Super-resolution Imaging

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17 Dec 2014
publication

Metagenomic chromosome conformation capture (meta3C) unveils the diversity of chromosome organization in microorganisms

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17 Dec 2014
publication

High-quality genome (re)assembly using chromosomal contact data.

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15 Sep 2014
department

Genomes and Genetics

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01 Jul 2014
publication

Gateway to genetic exchange? DNA double-strand breaks in the bdelloid rotifer Adineta vaga submitted to desiccation

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07 Apr 2014
publication

Filling annotation gaps in yeast genomes using genome-wide contact maps.

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27 Mar 2014
publication

Total synthesis of a functional designer eukaryotic chromosome

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26 Mar 2014
publication

Purification of G1 daughter cells from different Saccharomycetes species through an optimized centrifugal elutriation procedure

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21 Jul 2013
publication

Genomic evidence for ameiotic evolution in the bdelloid rotifer Adineta vaga

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30 Aug 2012
publication

A predictive computational model of the dynamic 3D interphase yeast nucleus

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30 Aug 2012
publication

Normalization of a chromosomal contact map

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01 Jun 2012
publication

The chiasmatype theory. A new interpretation of the maturation divisions. 1909

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01 Jun 2012
publication

The centenary of Janssens’s chiasmatype theory

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23 Oct 2009
publication

Dynamic chromosome movements during meiosis: a way to eliminate unwanted connections?

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01 Jan 2009
publication

Real-time imaging of meiotic chromosomes in Saccharomyces cerevisiae

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02 Dec 2008
publication

A prominent role for segmental duplications in modeling eukaryotic genomes

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26 Sep 2008
publication

Csm4, in collaboration with Ndj1, mediates telomere-led chromosome dynamics and recombination during yeast meiosis

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05 Sep 2008
publication

Segmental duplications arise from Pol32-dependent repair of broken forks through two alternative replication-based mechanisms

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27 Jun 2008
publication

Meiotic chromosomes move by linkage to dynamic actin cables with transduction of force through the nuclear envelope

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19 Feb 2006
publication

Stability of large segmental duplications in the yeast genome

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01 Jul 2004
publication

Genome evolution in yeasts

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01 Jan 2004
publication

Large-scale exploration of growth inhibition caused by overexpression of genomic fragments in Saccharomyces cerevisiae.

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18 Dec 2003
publication

Eucaryotic genome evolution through the spontaneous duplication of large chromosomal segments

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16 Jan 2003
publication

The complete mitochondrial genome sequence of the pathogenic yeast Candida (Torulopsis) glabrata

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