Ligne de temps
Romain Koszul
Responsable de Structure
27 mars 2024
publication
Chromosome-level genome assembly of the European green woodpecker Picus viridis.
Lire plus21 mars 2024
19 mars 2024
publication
Absence of chromosome axis protein recruitment prevents meiotic recombination chromosome-wide in the budding yeast Lachancea kluyveri.
Lire plus05 févr. 2024
04 janv. 2024
publication
Transcription-induced domains form the elementary constraining building blocks of bacterial chromosomes.
Lire plus24 nov. 2023
news
Congratulation to Romain Koszul for being awarded the Molecular and Cellular Biology, Genomics Medal of the Academie des Sciences
Lire plus22 nov. 2023
publication
Design, construction, and functional characterization of a tRNA neochromosome in yeast.
Lire plus08 nov. 2023
publication
Synthetic chromosome fusion: Effects on mitotic and meiotic genome structure and function.
Lire plus09 oct. 2023
01 oct. 2023
26 juil. 2023
publication
Neuroinvasion and anosmia are independent phenomena upon infection with SARS-CoV-2 and its variants.
Lire plus19 mai 2023
publication
Chromosome folding and prophage activation reveal specific genomic architecture for intestinal bacteria.
Lire plus01 nov. 2022
publication
Chromosomal assembly of the flat oyster (Ostrea edulis L.) genome as a new genetic resource for aquaculture.
Lire plus05 oct. 2022
publication
Depletion or cleavage of cohesin during anaphase differentially affects chromatin structure and segregation.
Lire plus15 sept. 2022
publication
Chromosome-scale assemblies of Acanthamoeba castellanii genomes provide insights into Legionella pneumophila infection-related chromatin reorganization.
Lire plus10 août 2022
publication
Karyotype engineering reveals spatio-temporal control of replication firing and gene contacts.
Lire plus07 juil. 2022
01 juin 2022
publication
Smc3 acetylation, Pds5 and Scc2 control the translocase activity that establishes cohesin-dependent chromatin loops.
Lire plus21 mars 2022
publication
Extended sister-chromosome catenation leads to massive reorganization of the E. coli genome.
Lire plus21 févr. 2022
01 janv. 2022
01 janv. 2022
17 nov. 2021
news
Romain Koszul and Martial Marbouty discuss the use of 3C to understand phage-bacteria interaction on La Méthode Scientifique – France Culture
Lire plus01 nov. 2021
08 oct. 2021
publication
Chromosome-level genome assembly reveals homologous chromosomes and recombination in asexual rotifer Adineta vaga.
Lire plus18 juin 2021
publication
Generation of gene-level resolution chromosome contact maps in bacteria and archaea.
Lire plus29 avr. 2021
publication
Closed and High-Quality Bacterial Genome Sequences of the Oligo-Mouse-Microbiota Community.
Lire plus26 févr. 2021
publication
MetaHiC phage-bacteria infection network reveals active cycling phages of the healthy human gut.
Lire plus12 févr. 2021
22 janv. 2021
publication
Chromosomal scale assembly of parasitic wasp genome reveals symbiotic virus colonization.
Lire plus22 déc. 2020
publication
Euryarchaeal genomes are folded into SMC-dependent loops and domains, but lack transcription-mediated compartmentalization.
Lire plus16 nov. 2020
21 juil. 2020
software
instaGRAAL: chromosome-level quality scaffolding of genomes using a proximity ligation-based scaffolder
Lire plus21 juil. 2020
software
Chromosight: A computer vision program for pattern detection in chromosome contact maps
Lire plus21 juil. 2020
21 juil. 2020
project
ERC-2017-COG Synarchic – Investigating the functional architecture of microbial genomes with synthetic approaches
Lire plus18 juin 2020
publication
instaGRAAL: chromosome-level quality scaffolding of genomes using a proximity ligation-based scaffolder.
Lire plus01 juin 2020
20 mars 2020
publication
Chromosome organization by a conserved condensin-ParB system in the actinobacterium Corynebacterium glutamicum.
Lire plus28 janv. 2020
18 déc. 2019
03 oct. 2019
20 août 2019
publication
MetaTOR: A Computational Pipeline to Recover High-Quality Metagenomic Bins From Mammalian Gut Proximity-Ligation (meta3C) Libraries
Lire plus30 mai 2019
publication
Condensin-Mediated Chromosome Folding and Internal Telomeres Drive Dicentric Severing by Cytokinesis
Lire plus21 févr. 2019
05 févr. 2019
15 oct. 2018
publication
Tridimensional infiltration of DNA viruses into the host genome shows preferential contact with active chromatin.
Lire plus18 sept. 2018
publication
Generation of a Metagenomics Proximity Ligation 3C Library of a Mammalian Gut Microbiota
Lire plus03 août 2018
16 juil. 2018
publication
Characterizing meiotic chromosomes’ structure and pairing using a designer sequence optimized for Hi-C
Lire plus24 févr. 2018
publication
A Proximity Ligation-Based Method for Quantitative Measurement of D-Loop Extension in S. cerevisiae
Lire plus10 janv. 2018
publication
Multiscale Structuring of the E. coli Chromosome by Nucleoid-Associated and Condensin Proteins
Lire plus20 juil. 2017
publication
Cohesins and condensins orchestrate the 4D dynamics of yeast chromosomes during the cell cycle
Lire plus12 juin 2017
publication
Proximity ligation scaffolding and comparison of two Trichoderma reesei strains genomes
Lire plus10 mars 2017
10 mars 2017
17 févr. 2017
publication
Scaffolding bacterial genomes and probing host-virus interactions in gut microbiome by proximity ligation (chromosome capture) assay
Lire plus01 janv. 2017
08 juin 2016
01 avr. 2016
publication
A checkpoint control orchestrates the replication of the two chromosomes of Vibrio cholerae.
Lire plus05 janv. 2016
publication
Evidence for actin dual role in regulating chromosome organization and dynamics in yeast
Lire plus01 janv. 2016
24 nov. 2015
publication
The 3D folding of metazoan genomes correlates with the association of similar repetitive elements
Lire plus19 nov. 2015
publication
Metagenome Analysis Exploiting High-Throughput Chromosome Conformation Capture (3C) Data
Lire plus09 nov. 2015
project
ERC-2010-StG Interaction dynamique entre chromosomes eucaryotes : impact sur la stabilité du génome (DICIG)
Lire plus01 oct. 2015
23 sept. 2015
11 sept. 2015
02 sept. 2015
21 août 2015
publication
Filling the gap: Micro-C accesses the nucleosomal fiber at 100-1000 bp resolution
Lire plus15 juin 2015
11 mai 2015
29 avr. 2015
publication
Contact genomics: scaffolding and phasing (meta)genomes using chromosome 3D physical signatures
Lire plus25 janv. 2015
publication
Condensin- and Replication-Mediated Bacterial Chromosome Folding and Origin Condensation Revealed by Hi-C and Super-resolution Imaging
Lire plus17 déc. 2014
publication
Metagenomic chromosome conformation capture (meta3C) unveils the diversity of chromosome organization in microorganisms
Lire plus17 déc. 2014
15 sept. 2014
01 juil. 2014
publication
Gateway to genetic exchange? DNA double-strand breaks in the bdelloid rotifer Adineta vaga submitted to desiccation
Lire plus07 avr. 2014
27 mars 2014
26 mars 2014
publication
Purification of G1 daughter cells from different Saccharomycetes species through an optimized centrifugal elutriation procedure
Lire plus21 juil. 2013
30 août 2012
30 août 2012
01 juin 2012
publication
The chiasmatype theory. A new interpretation of the maturation divisions. 1909
Lire plus01 juin 2012
23 oct. 2009
publication
Dynamic chromosome movements during meiosis: a way to eliminate unwanted connections?
Lire plus01 janv. 2009
02 déc. 2008
26 sept. 2008
publication
Csm4, in collaboration with Ndj1, mediates telomere-led chromosome dynamics and recombination during yeast meiosis
Lire plus05 sept. 2008
publication
Segmental duplications arise from Pol32-dependent repair of broken forks through two alternative replication-based mechanisms
Lire plus27 juin 2008
publication
Meiotic chromosomes move by linkage to dynamic actin cables with transduction of force through the nuclear envelope
Lire plus19 févr. 2006
01 juil. 2004
01 janv. 2004
publication
Large-scale exploration of growth inhibition caused by overexpression of genomic fragments in Saccharomyces cerevisiae.
Lire plus18 déc. 2003
publication
Eucaryotic genome evolution through the spontaneous duplication of large chromosomal segments
Lire plus16 janv. 2003
publication