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Responsable de Structure
Responsable de Plateforme
Groupe : Régis Tournebize
PTR 496 – Investigating the reciprocal relationship between macrophage inflammasome activity and intracellular Leishmania infection
Eric Prina (PI)
Our proposal aims to decipher novel subversion strategies used by Leishmania (i) to withstand, circumvent or inhibit anti-microbial activities of host macrophages and (ii) to interfere with the induction of Leishmania-specific immune responses. We […]
How the dynamics of signaling complexes at the immunological synapse controls T cell activation
Vincenzo Di Bartolo (PI)
Signals generated by the engagement of the T cell antigen receptor are decoded and integrated by molecular complexes that form at the immunological synapse upon T cell receptor engagement. Assembly of these complexes, as […]
INCEPTION – INstitut Convergences pour l’étude de l’Émergence des Pathologies au Travers des Individus et des populatiONs et des
Désolé, cet article est seulement disponible en Anglais Américain.
Institut Carnot Pasteur MS
Le label Carnot vise à reconnaître la capacité de structures de recherche à collaborer avec des partenaires socio- économiques, notamment des entreprises, tout en renforçant leur visibilité. Un institut Canot (IC) labélisé bénéficie de moyens […]
Jean-Yves Tinevez (PI)
MaMuT is an end user plugin that combines the BigDataViewer and TrackMate to provide an application that allow browsing, annotating and curating annotations for large, multi-view images. Built in collaboration with Tobias Pietzsch, along with the group of […]
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Spinning-disk Ti2E Inverted microscope, equipped with a Yokagawa CSU-W1 spinning disk with 2 pinhole size, and two cameras: a more sensitive and another more resolutive. It allows the fast acquisition of optically sectioned slices at […]
imaging in aqueous buffers and organic solvent optical zoom from 1.26x to 12.6x large sample uptake up to 30 mm x 30 mm x 15 mm dynamic horizontal focusing for better Z resolution 6 […]
Small animal pre-clinical in vivo imaging system dedicated to 3D imaging of fluorescence signal (Fluorescence Molecular Tomography). The system is equipped with 4 lasers in the Near Infra Red and is calibrated for quantifying […]
Small animal pre-clinical in vivo imaging systems dedicated to 2D and 3D imaging of bioluminescence and fluorescence signals. The system is equipped with 10 excitation filters and 18 emission filters, and a high sensitive […]
Small animal pre-clinical in vivo imaging systems dedicated to 2D and 3D imaging of bioluminescence and fluorescence signals. Each system is equipped with 10 excitation filters and 18 emission filters, and a high sensitive […]
Presentation. The Yokagawa CellVoyager CV1000 is an automated microscope based on the spinning-disk technology. It excels at multi-scale microscopy, when locating rare events in a large sample is needed. Applications typically consist in […]
Presentation. The CODIM 100 is a super-resolution microscope that specialized in imaging live-cell. It is the fruit of a collaboration between the Imagopole and the BioAxial company, on the development of an entirely new approach […]
Inverted microscope fully motorized, equipped with a laser scanning confocal head. It allows the acquisition in spectral mode, multi-positions, multi-mosaics, and autofocus control with sensitive detectors. Features : Available light sources 405 nm […]
Inverted microscope fully motorized, equipped with a laser scanning confocal head. It allows the acquisition in spectral mode, multi-positions, multi-mosaics. Features : Available light sources 405 nm White laser 470-670 nm Mercury […]
Spinning-disk UltraView VOX Inverted microscope, equipped with a Yokagawa CSUX1 spinning- disk, and two cameras to do dual-color simultaneous imaging. It allows the fast acquisition of optically sectioned slices at very high speed, and is […]
Inverted confocal microscope (780 head) coupled with two techniques of super resolution SIM and PALM STORM (Elyra PS.1 head) SR SIM : Super resolution structured illumination PALM/STORM : Photoactivated Localization Microscopy / Stochastic Optical […]
Inverted widefield Microscope equipped with apotome grid allowing global fluorescence and optical sections imaging . Features : Available light sources Mercury Lamp HBO 100 Available filters Fluorescence Excitation Dichroic Emission DAPI BP […]
Upright widefield Microscope equipped with apotome2 grids allowing global fluorescence and optical sections imaging and a color camera allowing the observation of histological slices. Features : Available light sources Mercury Lamp HXP 120 […]
Biostation IM-Q The Biostation is a live cell recorder made for very long term imaging of live cells. It is built around an incubation chamber where temperature, CO2 and humidity are controlled as in […]
Inverted widefield Microscope equipped with LED colibris allowing acquisition on live fluorescent samples with the module ” Fast Acquisition “. Features : Available light sources LED colibri 365 nm 470 nm 555 […]
Inverted widefield Microscope equipped with LED colibris and mercury lamp allowing acquisition on live fluorescent samples with control of the focus using the ‘Definite Focus’ module. Features : Available light sources Mercury Lamp […]
High Throughput confocal microscope for fully automated simultaneous high speed and high-resolution image captures. Specifications Light Sources Laser Violet wavelength 405 nm, power 50 mW Laser Blue: wavelength 488 nm, power 200 […]
Inverted microscope, equipped with a laser scanning confocal head. It allows the acquisition of optically sectioned slices. Features : Available light sources 405 nm 488 nm 555 nm 639 nm Halogen lamp […]
2019Discovery of novel hit compounds with broad activity against visceral and cutaneous Leishmania species by comparative phenotypic screening, Sci Rep 2019 Jan;9(1):438.
2018Effect of Helicobacter pylori Infection on GATA-5 and TFF1 Regulation, Comparison Between Pediatric and Adult Patients, Dig. Dis. Sci. 2018 11;63(11):2889-2897.
2018Penetration of the Human Pulmonary Epithelium by Aspergillus fumigatus Hyphae, J. Infect. Dis. 2018 Sep;218(8):1306-1313.
2018Multi-view light-sheet imaging and tracking with the MaMuT software reveals the cell lineage of a direct developing arthropod limb, Elife 2018 Mar;7.
2018Phosphoinositides regulate the TCR/CD3 complex membrane dynamics and activation, Sci Rep 2018 Mar;8(1):4966.
2018Fluorescence imaging host pathogen interactions: fifteen years benefit of hindsight…, Curr. Opin. Microbiol. 2018 06;43:193-198.
2018Imaging Intermediate Filaments and Microtubules with 2-dimensional Direct Stochastic Optical Reconstruction Microscopy., J Vis Exp. 2018 Mar 6;(133). doi: 10.3791/57087..
2018Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors, Nat. Immunol. 2018 Mar;19(3):302-314.
2018Rhinoscleroma pathogenesis: The type K3 capsule of Klebsiella rhinoscleromatis is a virulence factor not involved in Mikulicz cells formation, PLoS Negl Trop Dis 2018 Jan;12(1):e0006201.
2017Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges, Proc. Natl. Acad. Sci. U.S.A. 2018 01;115(3):E488-E497.
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