Timeline

Bruno Dupuy
Head of Structure
13 May 2019
publication

The Ser/Thr kinase PrkC participates in cell wall homeostasis and antimicrobial resistance in

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09 May 2019
publication

A microbiota-generated bile salt induces biofilm formation in

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29 Apr 2019
publication

The σ signalling activation pathway in the enteropathogen Clostridioides difficile

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18 Mar 2019
publication

Role of the global regulator Rex in control of NAD -regeneration in Clostridioides (Clostridium) difficile

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25 Feb 2019
project

Biofilms formed by anaerobes

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21 Feb 2019
publication

CotL, a new morphogenetic spore coat protein of Clostridium difficile

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20 Aug 2018
publication

Clostridium difficile biofilm: remodeling metabolism and cell surface to build a sparse and heterogeneously aggregated architecture

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29 Jul 2018
publication

A microfluidic fluidized bed to capture, amplify and detect bacteria from raw samples

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12 Jun 2018
publication

Cwp19 Is a Novel Lytic Transglycosylase Involved in Stationary-Phase Autolysis Resulting in Toxin Release in

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28 Mar 2018
publication

Micro-nano-bio acoustic system for the detection of foodborne pathogens in real samples

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12 Mar 2018
publication

Pleiotropic roles of Clostridium difficile sin locus

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26 Feb 2018
publication

Discovery of new type I toxin-antitoxin systems adjacent to CRISPR arrays in Clostridium difficile

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17 Nov 2017
publication

High prevalence and genetic diversity of large phiCD211/phiCDIF1296T-like prophages in Clostridioides difficile

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04 Sep 2017
publication

Advanced immunocapture of milk-borne Salmonella by microfluidic magnetically stabilized fluidized bed

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21 Mar 2017
publication

The alternative sigma factor σ plays a crucial role in adaptive strategies of Clostridium difficile during gut infection

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15 Feb 2017
publication

Effect of tcdR Mutation on Sporulation in the Epidemic Clostridium difficile Strain R20291

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10 Oct 2016
publication

A new microfluidic approach for the one-step capture, amplification and label-free quantification of bacteria from raw samples

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23 Sep 2016
project

Prophage elements as a significant source of genetic diversity among epidemic C. difficile 027 strains

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22 Sep 2016
course

Workshop: Bacterial RNAseq

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21 Sep 2016
publication

What’s a SNP between friends: The influence of single nucleotide polymorphisms on virulence and phenotypes of Clostridium difficile strain 630 and derivatives

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15 Sep 2016
publication

A Recombination Directionality Factor Controls the Cell Type-Specific Activation of σK and the Fidelity of Spore Development in Clostridium difficile

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31 Aug 2016
publication

Phylogenomic analysis supports the ancestral presence of LPS-outer membranes in the Firmicutes

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21 Jul 2016
publication

Control of Clostridium difficile Physiopathology in Response to Cysteine Availability

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28 Jun 2016
publication

Deciphering Adaptation Strategies of the Epidemic Clostridium difficile 027 Strain during Infection through In Vivo Transcriptional Analysis

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14 May 2016
publication

The Regulatory Networks That Control Clostridium difficile Toxin Synthesis

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26 Mar 2016
publication

Cpe1786/IscR of Clostridium perfringens represses expression of genes involved in Fe-S cluster biogenesis

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01 Jan 2016
publication

Micro-Nano-Bio Diagnostic System for Food Pathogen Detection Revolutionizes Food Safety Management & Protects Consumers Health

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11 Nov 2015
publication

Plasma nanotextured polymeric lab-on-a-chip for highly efficient bacteria capture and lysis

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09 Nov 2015
event

Phage Bacteria interactions in Clostridium difficile

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14 Oct 2015
project

Biology of anaerobic biofilm formed by Clostridium difficile and their role in  infections

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13 Oct 2015
project

The regulatory network of sporulation and spore morphogenesis in Clostridium difficile

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01 Sep 2015
publication

Function of the CRISPR-Cas System of the Human Pathogen Clostridium difficile

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17 Aug 2015
software

COV2HTML

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11 May 2015
team

Pathogenesis of Bacterial Anaerobes

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10 Jan 2015
publication

Repressor activity of the RpoS/σS-dependent RNA polymerase requires DNA binding

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01 Dec 2014
publication

Inter- and intraspecies transfer of a Clostridium difficile conjugative transposon conferring resistance to MLSB

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15 Oct 2014
publication

Integration of metabolism and virulence in Clostridium difficile

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15 Sep 2014
department

Microbiology

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30 Jun 2014
publication

Pleiotropic role of the RNA chaperone protein Hfq in the human pathogen Clostridium difficile

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09 Jun 2014
publication

Multidisciplinary analysis of a nontoxigenic Clostridium difficile strain with stable resistance to metronidazole

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19 May 2014
publication

The flagellin FliC of Clostridium difficile is responsible for pleiotropic gene regulation during in vivo infection

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08 May 2014
publication

Expanding the RpoS/σS-network by RNA sequencing and identification of σS-controlled small RNAs in Salmonella

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08 Apr 2014
publication

The LexA regulated genes of the Clostridium difficile

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10 Feb 2014
publication

COV2HTML: a visualization and analysis tool of bacterial next generation sequencing (NGS) data for postgenomics life scientists

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23 Jan 2014
publication

Sequence similarity of Clostridium difficile strains by analysis of conserved genes and genome content is reflected by their ribotype affiliation

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16 Dec 2013
publication

Characterization of the SigD regulon of C. difficile and its positive control of toxin production through the regulation of tcdR

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03 Oct 2013
publication

Genome-wide analysis of cell type-specific gene transcription during spore formation in Clostridium difficile

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16 Sep 2013
project

Control of toxin synthesis and secretion in Clostridium difficile

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09 May 2013
publication

Genome-wide identification of regulatory RNAs in the human pathogen Clostridium difficile

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18 Sep 2012
publication

Global transcriptional control by glucose and carbon regulator CcpA in Clostridium difficile

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07 Jun 2012
publication

Secretion of Clostridium difficile toxins A and B requires the holin-like protein TcdE

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13 Oct 2011
publication

The anti-sigma factor TcdC modulates hypervirulence in an epidemic BI/NAP1/027 clinical isolate of Clostridium difficile

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13 Apr 2011
publication

Rapid diagnosis of Clostridium difficile infection by multiplex real-time PCR

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28 Dec 2010
publication

CcpA-mediated repression of Clostridium difficile toxin gene expression

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07 Sep 2010
publication

Global regulation of gene expression in response to cysteine availability in Clostridium perfringens

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26 Feb 2010
publication

Characterization of Acp, a peptidoglycan hydrolase of Clostridium perfringens with N-acetylglucosaminidase activity that is implicated in cell separation and stress-induced autolysis

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01 Jan 2010
publication

Molecular methods to study transcriptional regulation of Clostridium difficile toxin genes

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05 Oct 2009
publication

Effects of subinhibitory concentrations of antibiotics on colonization factor expression by moxifloxacin-susceptible and moxifloxacin-resistant Clostridium difficile strains

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23 Sep 2009
publication

Bacteriophage-mediated toxin gene regulation in Clostridium difficile

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17 Aug 2009
project

Pathogenomic analysis of high potential virulent strains of C. difficile

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01 Jun 2008
publication

Clostridium difficile toxin synthesis is negatively regulated by TcdC

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01 Jun 2007
publication

Clostridium difficile toxin expression is inhibited by the novel regulator TcdC

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25 Jun 2006
publication

The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome

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01 May 2006
publication

Regulation of toxin and bacteriocin gene expression in Clostridium by interchangeable RNA polymerase sigma factors

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01 Jan 2006
publication

Isolation of RNA polymerase from Clostridium difficile and characterization of glutamate dehydrogenase and rRNA gene promoters in vitro and in vivo

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29 Dec 2005
publication

Regulation of toxin and bacteriocin synthesis in Clostridium species by a new subgroup of RNA polymerase sigma-factors

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01 Feb 2005
publication

Revised nomenclature of Clostridium difficile toxins and associated genes

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01 Feb 2005
publication

Transcription activation of a UV-inducible Clostridium perfringens bacteriocin gene by a novel sigma factor

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01 Jan 2005
publication

BotR/A and TetR are alternative RNA polymerase sigma factors controlling the expression of the neurotoxin and associated protein genes in Clostridium botulinum type A and Clostridium tetani

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01 Jun 2004
publication

The spatial organization of the VirR boxes is critical for VirR-mediated expression of the perfringolysin O gene, pfoA, from Clostridium perfringens

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01 Apr 2004
publication

Organization and regulation of the neurotoxin genes in Clostridium botulinum and Clostridium tetani

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01 Apr 2003
publication

Expression of Clostridium difficile toxins A and B and their sigma factor TcdD is controlled by temperature

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01 Nov 2002
publication

Environmental response and autoregulation of Clostridium difficile TxeR, a sigma factor for toxin gene expression

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24 Apr 2001
publication

Regulation of toxin synthesis in Clostridium difficile by an alternative RNA polymerase sigma factor

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01 Jan 1998
publication

Regulated transcription of Clostridium difficile toxin genes

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01 Jun 1997
publication

Clostridium perfringens urease genes are plasmid borne

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26 Jul 1996
publication

Genome mapping of Clostridium perfringens strains with I-CeuI shows many virulence genes to be plasmid-borne

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01 Oct 1995
publication

Rapid expansion of the physical and genetic map of the chromosome of Clostridium perfringens CPN50

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01 Mar 1994
publication

Type IV prepilin peptidase gene of Neisseria gonorrhoeae MS11: presence of a related gene in other piliated and nonpiliated Neisseria strains

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01 Sep 1992
publication

Role of pilA, an essential regulatory gene of Neisseria gonorrhoeae, in the stress response

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01 Jul 1992
publication

PulO, a component of the pullulanase secretion pathway of Klebsiella oxytoca, correctly and efficiently processes gonococcal type IV prepilin in Escherichia coli

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01 Mar 1992
publication

An enzyme with type IV prepilin peptidase activity is required to process components of the general extracellular protein secretion pathway of Klebsiella oxytoca

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01 Dec 1991
publication

Neisseria gonorrhoeae prepilin export studied in Escherichia coli

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01 Jan 1991
publication

Control of pilus expression in Neisseria gonorrhoeae as an original system in the family of two-component regulators

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